Motif ID: Pou6f2_Pou4f2

Z-value: 0.797

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f2mm10_v2_chr8_-_78436640_784366490.575.3e-04Click!
Pou6f2mm10_v2_chr13_-_18382041_183820410.261.5e-01Click!


Activity profile for motif Pou6f2_Pou4f2.

activity profile for motif Pou6f2_Pou4f2


Sorted Z-values histogram for motif Pou6f2_Pou4f2

Sorted Z-values for motif Pou6f2_Pou4f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 99 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_31949571 5.995 ENSMUST00000064016.5
 Gpr17
G protein-coupled receptor 17
chr6_+_63255971 5.675 ENSMUST00000159561.1
ENSMUST00000095852.3
 Grid2

glutamate receptor, ionotropic, delta 2

chr2_+_109917639 5.303 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr13_-_56296551 4.876 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr10_+_99263224 3.729 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr13_-_81570640 3.471 ENSMUST00000109565.2
 Gpr98
G protein-coupled receptor 98
chr5_-_62766153 3.249 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_27039001 3.194 ENSMUST00000035336.3
 Il17rd
interleukin 17 receptor D
chr12_-_56535047 3.090 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr5_-_62765618 2.714 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_49564262 2.575 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr10_-_70655934 2.535 ENSMUST00000162144.1
ENSMUST00000162793.1
 Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr4_+_117849193 2.516 ENSMUST00000132043.2
ENSMUST00000169990.1
 Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr1_-_72874877 2.472 ENSMUST00000027377.8
 Igfbp5
insulin-like growth factor binding protein 5
chr4_+_117849361 2.445 ENSMUST00000163288.1
 Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_+_172341197 2.417 ENSMUST00000056136.3
 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr6_+_88724828 2.298 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr7_-_49636847 2.194 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr19_+_3323301 2.157 ENSMUST00000025835.4
 Cpt1a
carnitine palmitoyltransferase 1a, liver
chr6_+_88724667 1.868 ENSMUST00000163271.1
 Mgll
monoglyceride lipase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 6.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.4 5.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.8 5.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.7 5.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.6 4.9 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 4.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.6 4.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.2 3.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.3 3.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
1.0 3.1 GO:0021759 globus pallidus development(GO:0021759)
0.2 2.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 2.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 2.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.8 2.4 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 2.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.8 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.6 GO:0001553 luteinization(GO:0001553)
0.1 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 1.4 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.2 1.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.9 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.3 4.2 GO:0043196 varicosity(GO:0043196)
0.1 3.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.5 GO:0098793 presynapse(GO:0098793)
0.6 2.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.2 2.4 GO:0097449 astrocyte projection(GO:0097449)
0.1 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 5.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.9 5.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 5.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 4.9 GO:0008009 chemokine activity(GO:0008009)
0.3 4.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 4.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 3.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.1 3.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 3.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.3 3.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 3.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 2.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 2.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.8 2.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 2.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 2.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.3 GO:0003785 actin monomer binding(GO:0003785)