Motif ID: Pou6f2_Pou4f2
Z-value: 0.797
Transcription factors associated with Pou6f2_Pou4f2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou4f2 | ENSMUSG00000031688.3 | Pou4f2 |
Pou6f2 | ENSMUSG00000009734.11 | Pou6f2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou4f2 | mm10_v2_chr8_-_78436640_78436649 | 0.57 | 5.3e-04 | Click! |
Pou6f2 | mm10_v2_chr13_-_18382041_18382041 | 0.26 | 1.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 5.3 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
1.7 | 5.0 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
1.6 | 4.9 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
1.2 | 3.7 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
1.0 | 3.1 | GO:0021759 | globus pallidus development(GO:0021759) |
0.8 | 2.4 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
0.7 | 6.0 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.6 | 4.2 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.4 | 5.7 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.4 | 1.1 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.4 | 2.5 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.3 | 1.4 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
0.3 | 1.0 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
0.3 | 2.5 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.3 | 3.7 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
0.2 | 0.7 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.2 | 0.6 | GO:0036233 | glycine import(GO:0036233) |
0.2 | 1.1 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.2 | 2.2 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.2 | 1.2 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.2 | 2.7 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
0.1 | 4.5 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.1 | 0.5 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
0.1 | 0.5 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.1 | 1.0 | GO:0050957 | equilibrioception(GO:0050957) |
0.1 | 0.7 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.1 | 1.6 | GO:0001553 | luteinization(GO:0001553) |
0.1 | 0.5 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.1 | 0.5 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.1 | 0.4 | GO:0046909 | intermembrane transport(GO:0046909) |
0.1 | 1.1 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.1 | 1.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 0.8 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.1 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.0 | 0.7 | GO:0001780 | neutrophil homeostasis(GO:0001780) regulation of high voltage-gated calcium channel activity(GO:1901841) |
0.0 | 0.1 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.0 | 0.8 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 1.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.3 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
0.0 | 1.2 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 1.8 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
0.0 | 0.1 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
0.0 | 1.2 | GO:0030168 | platelet activation(GO:0030168) |
0.0 | 0.6 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.2 | GO:0002021 | response to dietary excess(GO:0002021) |
0.0 | 0.4 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.5 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
0.3 | 4.2 | GO:0043196 | varicosity(GO:0043196) |
0.2 | 1.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.2 | 1.2 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.2 | 2.4 | GO:0097449 | astrocyte projection(GO:0097449) |
0.1 | 3.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.1 | 2.0 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 4.9 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
0.1 | 0.5 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 0.5 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 0.8 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 5.1 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 3.5 | GO:0098793 | presynapse(GO:0098793) |
0.0 | 0.1 | GO:0031083 | BLOC-1 complex(GO:0031083) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.2 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
0.9 | 5.5 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
0.8 | 2.4 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
0.4 | 5.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.4 | 2.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
0.4 | 1.1 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.4 | 2.5 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.3 | 4.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.3 | 2.5 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.3 | 3.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.2 | 1.2 | GO:0008808 | cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) |
0.2 | 5.7 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
0.2 | 0.7 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
0.2 | 4.9 | GO:0008009 | chemokine activity(GO:0008009) |
0.1 | 1.2 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.1 | 0.5 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.1 | 0.5 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 6.0 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 4.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.1 | 3.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 1.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 1.3 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 1.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.3 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.0 | 0.5 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 2.1 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 3.2 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.0 | 0.4 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.0 | 0.7 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 0.3 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.0 | 2.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 3.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |