Motif ID: Ppara

Z-value: 2.242


Transcription factors associated with Ppara:

Gene SymbolEntrez IDGene Name
Ppara ENSMUSG00000022383.7 Ppara



Activity profile for motif Ppara.

activity profile for motif Ppara


Sorted Z-values histogram for motif Ppara

Sorted Z-values for motif Ppara



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppara

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_35910032 18.197 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
 Atat1




alpha tubulin acetyltransferase 1




chr3_+_95164306 15.409 ENSMUST00000107217.1
ENSMUST00000168321.1
 Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr17_-_35909626 14.811 ENSMUST00000141132.1
 Atat1
alpha tubulin acetyltransferase 1
chr12_+_61523889 13.826 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr8_-_84773381 13.782 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr2_+_170731807 13.545 ENSMUST00000029075.4
 Dok5
docking protein 5
chr11_-_98329641 13.041 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr15_-_66801577 12.586 ENSMUST00000168589.1
 Sla
src-like adaptor
chr1_+_6214627 12.081 ENSMUST00000027040.6
 Rb1cc1
RB1-inducible coiled-coil 1
chr8_+_124793013 11.715 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr12_+_29528382 11.534 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr5_+_35056813 11.446 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
 Dok7


docking protein 7


chr7_-_141429433 11.280 ENSMUST00000124444.1
 Cend1
cell cycle exit and neuronal differentiation 1
chr7_-_141429351 11.258 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr7_-_25005895 11.203 ENSMUST00000102858.3
ENSMUST00000080882.6
 Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr18_+_77185815 11.102 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr8_+_124793061 11.051 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr5_+_117781017 10.782 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr11_-_6065538 10.395 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr15_+_80091320 10.303 ENSMUST00000009728.6
ENSMUST00000009727.5
 Syngr1

synaptogyrin 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 307 entries
Log-likelihood per target Total log-likelihoodTermDescription
11.0 33.0 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.8 31.5 GO:0006376 mRNA splice site selection(GO:0006376)
2.6 23.7 GO:0071420 cellular response to histamine(GO:0071420)
7.5 22.5 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.9 21.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.6 20.2 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
2.3 18.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.5 18.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.7 17.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.8 15.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.1 13.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.8 13.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.4 13.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
1.9 13.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
4.3 13.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 12.6 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
1.5 12.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.6 11.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 11.0 GO:1902476 chloride transmembrane transport(GO:1902476)
2.7 10.8 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 119 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 51.4 GO:0016021 integral component of membrane(GO:0016021)
5.5 33.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 30.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.6 28.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 20.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
2.0 20.3 GO:0044327 dendritic spine head(GO:0044327)
1.1 18.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 18.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 16.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 15.3 GO:0005884 actin filament(GO:0005884)
0.1 14.7 GO:0045202 synapse(GO:0045202)
0.3 14.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 12.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
3.0 12.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 12.1 GO:0043197 dendritic spine(GO:0043197)
0.6 12.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 11.8 GO:0030427 site of polarized growth(GO:0030427)
0.6 11.3 GO:0032279 asymmetric synapse(GO:0032279)
1.0 10.8 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
2.7 10.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 218 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 39.3 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.6 26.0 GO:0005158 insulin receptor binding(GO:0005158)
3.8 22.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.3 21.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.5 19.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.0 18.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.6 18.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.6 16.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.9 15.3 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.7 15.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.9 15.2 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.3 15.0 GO:0070888 E-box binding(GO:0070888)
0.4 13.8 GO:0050699 WW domain binding(GO:0050699)
0.4 13.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.2 13.3 GO:0038191 neuropilin binding(GO:0038191)
1.1 13.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 11.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
3.6 10.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 10.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 10.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)