Motif ID: Ppard

Z-value: 0.392


Transcription factors associated with Ppard:

Gene SymbolEntrez IDGene Name
Ppard ENSMUSG00000002250.9 Ppard

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ppardmm10_v2_chr17_+_28232723_282327890.192.8e-01Click!


Activity profile for motif Ppard.

activity profile for motif Ppard


Sorted Z-values histogram for motif Ppard

Sorted Z-values for motif Ppard



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppard

PNG image of the network

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Top targets:


Showing 1 to 20 of 71 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 2.867 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr9_-_57262591 0.890 ENSMUST00000034846.5
 1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr4_+_118429701 0.873 ENSMUST00000067896.3
 Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr9_-_51278540 0.850 ENSMUST00000114427.3
 Gm684
predicted gene 684
chr10_-_13324160 0.811 ENSMUST00000105545.4
 Phactr2
phosphatase and actin regulator 2
chr4_+_59581563 0.782 ENSMUST00000030078.5
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr3_+_98280427 0.745 ENSMUST00000090746.2
ENSMUST00000120541.1
 Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr1_-_120120138 0.738 ENSMUST00000112648.1
ENSMUST00000128408.1
 Dbi

diazepam binding inhibitor

chr4_+_59581645 0.727 ENSMUST00000107528.1
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr17_-_34028044 0.715 ENSMUST00000045467.7
ENSMUST00000114303.3
 H2-Ke6

H2-K region expressed gene 6

chr3_-_8923796 0.702 ENSMUST00000042148.5
 Mrps28
mitochondrial ribosomal protein S28
chr11_-_4704334 0.683 ENSMUST00000058407.5
 Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr8_-_111393810 0.666 ENSMUST00000038475.8
 Fa2h
fatty acid 2-hydroxylase
chr11_+_70657687 0.654 ENSMUST00000134087.1
ENSMUST00000170716.1
 Eno3

enolase 3, beta muscle

chr5_-_115119277 0.621 ENSMUST00000031524.7
 Acads
acyl-Coenzyme A dehydrogenase, short chain
chr15_+_25773985 0.575 ENSMUST00000125667.1
 Myo10
myosin X
chr5_-_31697598 0.568 ENSMUST00000031018.7
 Rbks
ribokinase
chr5_+_129725063 0.557 ENSMUST00000086046.3
 Gbas
glioblastoma amplified sequence
chr3_-_138131356 0.525 ENSMUST00000029805.8
 Mttp
microsomal triglyceride transfer protein
chr5_-_110286159 0.523 ENSMUST00000031472.5
 Pxmp2
peroxisomal membrane protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.9 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
0.1 1.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.7 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.7 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.2 0.6 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 0.6 GO:0019321 pentose metabolic process(GO:0019321)
0.2 0.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.3 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 1.0 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 1.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.9 GO:0019841 retinol binding(GO:0019841)
0.1 2.2 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 1.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.8 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.2 0.7 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.7 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)