Motif ID: Pparg_Rxrg

Z-value: 1.192

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167598384_167598411-0.125.2e-01Click!


Activity profile for motif Pparg_Rxrg.

activity profile for motif Pparg_Rxrg


Sorted Z-values histogram for motif Pparg_Rxrg

Sorted Z-values for motif Pparg_Rxrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103843154 9.965 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr12_+_109452833 8.048 ENSMUST00000056110.8
 Dlk1
delta-like 1 homolog (Drosophila)
chr3_+_87948666 7.064 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr7_+_4925802 6.550 ENSMUST00000057612.7
 Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr19_-_43912392 4.932 ENSMUST00000026209.4
 Dnmbp
dynamin binding protein
chr6_-_124813065 4.595 ENSMUST00000149610.2
 Tpi1
triosephosphate isomerase 1
chr5_-_137611372 4.284 ENSMUST00000054564.6
 Pcolce
procollagen C-endopeptidase enhancer protein
chr6_+_34354119 4.171 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chr18_-_41951187 4.136 ENSMUST00000070949.4
 Prelid2
PRELI domain containing 2
chr5_+_64970069 4.081 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chrX_+_73639414 4.078 ENSMUST00000019701.8
 Dusp9
dual specificity phosphatase 9
chr5_+_110286306 4.046 ENSMUST00000007296.5
ENSMUST00000112482.1
 Pole

polymerase (DNA directed), epsilon

chr17_-_56290499 3.961 ENSMUST00000019726.6
 Plin3
perilipin 3
chr13_-_24761861 3.928 ENSMUST00000006898.3
ENSMUST00000110382.2
 Gmnn

geminin

chr5_-_137611429 3.914 ENSMUST00000031731.7
 Pcolce
procollagen C-endopeptidase enhancer protein
chr5_-_31697598 3.855 ENSMUST00000031018.7
 Rbks
ribokinase
chr2_+_126556128 3.770 ENSMUST00000141482.2
 Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr12_-_16800674 3.521 ENSMUST00000162112.1
 Greb1
gene regulated by estrogen in breast cancer protein
chr11_-_77894096 3.515 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr9_+_65630552 3.360 ENSMUST00000055844.8
 Rbpms2
RNA binding protein with multiple splicing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 382 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 10.0 GO:0015671 oxygen transport(GO:0015671)
0.2 8.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.6 7.5 GO:0006000 fructose metabolic process(GO:0006000)
0.7 7.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 6.7 GO:0071229 cellular response to acid chemical(GO:0071229)
1.1 6.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.3 6.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.9 6.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 6.2 GO:0006446 regulation of translational initiation(GO:0006446)
1.0 5.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.2 5.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.7 4.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 4.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
1.5 4.6 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.6 4.3 GO:0019321 pentose metabolic process(GO:0019321)
1.4 4.2 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.7 4.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
1.3 3.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 3.8 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 3.8 GO:0046677 response to antibiotic(GO:0046677)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 170 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 13.1 GO:0031012 extracellular matrix(GO:0031012)
1.6 12.9 GO:0005833 hemoglobin complex(GO:0005833)
0.0 10.0 GO:0005730 nucleolus(GO:0005730)
0.1 9.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.5 6.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.8 6.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 5.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 5.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 4.5 GO:0005811 lipid particle(GO:0005811)
0.0 4.3 GO:0005903 brush border(GO:0005903)
0.0 4.3 GO:0005925 focal adhesion(GO:0005925)
0.8 4.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 3.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.9 3.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 3.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 3.3 GO:0070552 BRISC complex(GO:0070552)
0.0 3.2 GO:0005635 nuclear envelope(GO:0005635)
0.1 3.1 GO:0005876 spindle microtubule(GO:0005876)
1.0 3.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 267 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 10.0 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 9.4 GO:0016504 peptidase activator activity(GO:0016504)
0.9 7.8 GO:0001972 retinoic acid binding(GO:0001972)
0.4 7.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.8 7.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.2 6.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 6.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.6 6.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.5 5.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 5.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 5.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 5.8 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 5.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 5.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 4.9 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.1 4.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.7 4.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 4.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 4.2 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)