Motif ID: Ptf1a

Z-value: 0.407


Transcription factors associated with Ptf1a:

Gene SymbolEntrez IDGene Name
Ptf1a ENSMUSG00000026735.2 Ptf1a



Activity profile for motif Ptf1a.

activity profile for motif Ptf1a


Sorted Z-values histogram for motif Ptf1a

Sorted Z-values for motif Ptf1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Ptf1a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_79386943 1.231 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr11_+_78324200 1.173 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr4_-_64046925 0.716 ENSMUST00000107377.3
 Tnc
tenascin C
chr9_-_112234956 0.569 ENSMUST00000162097.1
ENSMUST00000159055.1
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr19_+_7056731 0.569 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1
chr2_+_26973416 0.478 ENSMUST00000014996.7
ENSMUST00000102891.3
 Adamts13

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

chr9_-_112187766 0.449 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr2_-_7395968 0.384 ENSMUST00000002176.6
 Celf2
CUGBP, Elav-like family member 2
chr4_-_155010984 0.359 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
 Plch2


phospholipase C, eta 2


chr5_-_99252839 0.336 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr3_+_75557530 0.333 ENSMUST00000161776.1
ENSMUST00000029423.8
 Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr9_-_112187898 0.312 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chrX_+_166238923 0.312 ENSMUST00000060210.7
ENSMUST00000112233.1
 Gpm6b

glycoprotein m6b

chr15_+_80097866 0.288 ENSMUST00000143928.1
 Syngr1
synaptogyrin 1
chr18_+_32377176 0.274 ENSMUST00000091967.5
ENSMUST00000025239.7
 Bin1

bridging integrator 1

chr11_-_96916448 0.255 ENSMUST00000103152.4
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr18_+_37477768 0.254 ENSMUST00000051442.5
 Pcdhb16
protocadherin beta 16
chr10_+_127501672 0.209 ENSMUST00000160019.1
ENSMUST00000160610.1
 Stac3

SH3 and cysteine rich domain 3

chr10_-_95417099 0.209 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chr9_+_106477269 0.207 ENSMUST00000047721.8
 Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr2_+_71981184 0.200 ENSMUST00000090826.5
ENSMUST00000102698.3
 Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr10_+_127501707 0.181 ENSMUST00000035839.2
 Stac3
SH3 and cysteine rich domain 3
chr2_-_91950386 0.172 ENSMUST00000111303.1
 Dgkz
diacylglycerol kinase zeta
chr11_-_96916366 0.168 ENSMUST00000144731.1
ENSMUST00000127048.1
 Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr1_+_36691487 0.166 ENSMUST00000081180.4
 Cox5b
cytochrome c oxidase subunit Vb
chr1_+_92910805 0.149 ENSMUST00000179711.1
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr11_-_96916407 0.145 ENSMUST00000130774.1
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr9_+_123021315 0.141 ENSMUST00000084733.5
 Tmem42
transmembrane protein 42
chr5_+_64970069 0.137 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chr8_-_13890233 0.136 ENSMUST00000033839.7
 Coprs
coordinator of PRMT5, differentiation stimulator
chr4_+_152096719 0.129 ENSMUST00000105661.3
ENSMUST00000084115.3
 Plekhg5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5

chr11_-_93965957 0.128 ENSMUST00000021220.3
 Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr7_-_140102367 0.123 ENSMUST00000142105.1
 Fuom
fucose mutarotase
chr10_+_90829538 0.121 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_108305941 0.121 ENSMUST00000044725.7
 Tcta
T cell leukemia translocation altered gene
chr5_+_34525797 0.113 ENSMUST00000125817.1
ENSMUST00000067638.7
 Sh3bp2

SH3-domain binding protein 2

chr11_-_6444352 0.111 ENSMUST00000093346.5
ENSMUST00000109737.2
 H2afv

H2A histone family, member V

chr1_+_20951666 0.111 ENSMUST00000038447.4
 Efhc1
EF-hand domain (C-terminal) containing 1
chr2_+_25500750 0.107 ENSMUST00000015239.3
 Fbxw5
F-box and WD-40 domain protein 5
chr8_-_105295934 0.107 ENSMUST00000057855.3
 Exoc3l
exocyst complex component 3-like
chr19_+_9982694 0.104 ENSMUST00000025563.6
 Fth1
ferritin heavy chain 1
chr1_+_92910758 0.101 ENSMUST00000027487.8
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr7_+_46396439 0.101 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr6_+_83078339 0.099 ENSMUST00000165164.2
ENSMUST00000092614.2
 Pcgf1

polycomb group ring finger 1

chr10_+_42678890 0.098 ENSMUST00000040718.5
 Ostm1
osteopetrosis associated transmembrane protein 1
chr4_-_88438900 0.097 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr11_-_100441006 0.095 ENSMUST00000092689.2
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr11_-_102185202 0.092 ENSMUST00000107156.2
 Lsm12
LSM12 homolog (S. cerevisiae)
chrX_+_101383726 0.087 ENSMUST00000119190.1
 Gjb1
gap junction protein, beta 1
chr3_-_75556759 0.084 ENSMUST00000162138.1
ENSMUST00000029424.5
ENSMUST00000161137.1
 Pdcd10


programmed cell death 10


chr18_+_34331132 0.083 ENSMUST00000072576.3
ENSMUST00000119329.1
 Srp19

signal recognition particle 19

chr11_-_100440928 0.081 ENSMUST00000107397.1
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr8_+_94857450 0.080 ENSMUST00000109521.3
 Polr2c
polymerase (RNA) II (DNA directed) polypeptide C
chr11_+_70017085 0.077 ENSMUST00000108589.2
 Dlg4
discs, large homolog 4 (Drosophila)
chr6_+_83078606 0.074 ENSMUST00000177177.1
ENSMUST00000176089.1
 Pcgf1

polycomb group ring finger 1

chr11_-_100441058 0.072 ENSMUST00000107399.2
ENSMUST00000092688.5
 Nt5c3b

5'-nucleotidase, cytosolic IIIB

chr17_+_7925990 0.072 ENSMUST00000036370.7
 Tagap
T cell activation Rho GTPase activating protein
chr7_-_144582392 0.072 ENSMUST00000033394.7
 Fadd
Fas (TNFRSF6)-associated via death domain
chr11_+_78465697 0.066 ENSMUST00000001126.3
 Slc46a1
solute carrier family 46, member 1
chr16_-_55283237 0.063 ENSMUST00000036412.3
 Zpld1
zona pellucida like domain containing 1
chr2_-_131175201 0.060 ENSMUST00000110218.2
 Spef1
sperm flagellar 1
chr2_+_164948219 0.058 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr2_-_175131864 0.057 ENSMUST00000108929.2
 Gm14399
predicted gene 14399
chr14_-_105176860 0.057 ENSMUST00000163545.1
 Rbm26
RNA binding motif protein 26
chr11_+_49247462 0.055 ENSMUST00000109194.1
 Mgat1
mannoside acetylglucosaminyltransferase 1
chr10_+_86021961 0.053 ENSMUST00000130320.1
 Fbxo7
F-box protein 7
chr3_+_138277489 0.042 ENSMUST00000004232.9
 Adh1
alcohol dehydrogenase 1 (class I)
chr14_-_118925314 0.042 ENSMUST00000004055.8
 Dzip1
DAZ interacting protein 1
chr14_+_75845093 0.042 ENSMUST00000110894.2
 Tpt1
tumor protein, translationally-controlled 1
chr18_+_24709436 0.040 ENSMUST00000037097.7
 Fhod3
formin homology 2 domain containing 3
chr11_+_98446826 0.040 ENSMUST00000019456.4
 Grb7
growth factor receptor bound protein 7
chr11_+_48800357 0.039 ENSMUST00000020640.7
 Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr11_+_86484647 0.039 ENSMUST00000020827.6
 Rnft1
ring finger protein, transmembrane 1
chr14_-_55944536 0.039 ENSMUST00000022834.6
 Cma1
chymase 1, mast cell
chr2_-_57113053 0.036 ENSMUST00000112627.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_-_102185239 0.034 ENSMUST00000021297.5
 Lsm12
LSM12 homolog (S. cerevisiae)
chr10_+_86022189 0.034 ENSMUST00000120344.1
ENSMUST00000117597.1
 Fbxo7

F-box protein 7

chr11_-_103344651 0.030 ENSMUST00000041385.7
 Arhgap27
Rho GTPase activating protein 27
chr2_-_118703963 0.025 ENSMUST00000104937.1
 Ankrd63
ankyrin repeat domain 63
chr11_+_120633719 0.024 ENSMUST00000181502.1
 Gm17586
predicted gene, 17586
chr7_+_19131686 0.024 ENSMUST00000165913.1
 Fbxo46
F-box protein 46
chr9_-_85749308 0.023 ENSMUST00000039213.8
 Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chrX_-_164076482 0.019 ENSMUST00000134272.1
 Siah1b
seven in absentia 1B
chr5_+_134099704 0.018 ENSMUST00000016088.8
 Gatsl2
GATS protein-like 2
chr5_+_114314941 0.017 ENSMUST00000124316.1
ENSMUST00000169347.1
 Myo1h

myosin 1H

chr11_-_109611417 0.017 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
 Wipi1


WD repeat domain, phosphoinositide interacting 1


chr11_+_82911253 0.015 ENSMUST00000164945.1
ENSMUST00000018989.7
 Unc45b

unc-45 homolog B (C. elegans)

chr11_-_118355496 0.014 ENSMUST00000017610.3
 Timp2
tissue inhibitor of metalloproteinase 2
chr15_-_79774408 0.014 ENSMUST00000023055.6
 Dnal4
dynein, axonemal, light chain 4
chr4_-_36056726 0.014 ENSMUST00000108124.3
 Lingo2
leucine rich repeat and Ig domain containing 2
chr9_-_108597558 0.014 ENSMUST00000006853.5
 P4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr2_-_125782834 0.013 ENSMUST00000053699.6
 Secisbp2l
SECIS binding protein 2-like
chr7_-_25718976 0.013 ENSMUST00000002683.2
 Ccdc97
coiled-coil domain containing 97
chr7_-_99182681 0.011 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr12_-_113307912 0.010 ENSMUST00000103418.1
 Ighg2b
immunoglobulin heavy constant gamma 2B
chr4_-_12087912 0.007 ENSMUST00000050686.3
 Tmem67
transmembrane protein 67
chr15_-_79774383 0.004 ENSMUST00000069877.5
 Dnal4
dynein, axonemal, light chain 4
chr11_+_101325063 0.003 ENSMUST00000041095.7
ENSMUST00000107264.1
 Aoc2

amine oxidase, copper containing 2 (retina-specific)

chr16_+_43762221 0.002 ENSMUST00000023390.4
 Drd3
dopamine receptor D3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.6 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.3 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.0 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.0 1.0 GO:0007601 visual perception(GO:0007601)
0.0 0.0 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0019841 retinol binding(GO:0019841)
0.2 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)