Motif ID: Rara

Z-value: 0.689


Transcription factors associated with Rara:

Gene SymbolEntrez IDGene Name
Rara ENSMUSG00000037992.10 Rara

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Raramm10_v2_chr11_+_98927785_989278180.475.6e-03Click!


Activity profile for motif Rara.

activity profile for motif Rara


Sorted Z-values histogram for motif Rara

Sorted Z-values for motif Rara



Network of associatons between targets according to the STRING database.



First level regulatory network of Rara

PNG image of the network

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Top targets:


Showing 1 to 20 of 71 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_94875600 4.710 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr6_+_30723541 3.215 ENSMUST00000115127.1
 Mest
mesoderm specific transcript
chr4_-_141599835 3.023 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
 Fblim1



filamin binding LIM protein 1



chr17_+_34593388 2.731 ENSMUST00000174532.1
 Pbx2
pre B cell leukemia homeobox 2
chr11_+_98960412 2.156 ENSMUST00000107473.2
 Rara
retinoic acid receptor, alpha
chr4_+_150853919 2.059 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr14_-_16575456 1.730 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr14_+_55618023 1.508 ENSMUST00000002395.7
 Rec8
REC8 homolog (yeast)
chr12_-_108893197 1.441 ENSMUST00000161154.1
ENSMUST00000161410.1
 Wars

tryptophanyl-tRNA synthetase

chr2_+_5845243 1.392 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr4_-_128609981 1.349 ENSMUST00000141040.1
ENSMUST00000147876.1
ENSMUST00000097877.2
 Zscan20


zinc finger and SCAN domains 20


chr1_-_175692624 1.339 ENSMUST00000027809.7
 Opn3
opsin 3
chr11_+_94629741 1.292 ENSMUST00000021239.6
 Lrrc59
leucine rich repeat containing 59
chr4_+_48045144 1.143 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr11_-_5915124 1.037 ENSMUST00000109823.2
ENSMUST00000109822.1
 Gck

glucokinase

chr4_+_32238950 0.957 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr12_+_87026564 0.944 ENSMUST00000110187.1
ENSMUST00000156162.1
 Tmem63c

transmembrane protein 63c

chr2_-_5012716 0.924 ENSMUST00000027980.7
 Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr2_+_5845017 0.897 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr6_-_6217023 0.875 ENSMUST00000015256.8
 Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 3.2 GO:0010883 regulation of lipid storage(GO:0010883)
0.2 3.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 2.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 2.3 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.7 2.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.7 2.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.3 1.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.5 GO:0007141 male meiosis I(GO:0007141)
0.5 1.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.4 1.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 1.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.3 1.0 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 0.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.2 0.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.7 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.7 GO:0006094 gluconeogenesis(GO:0006094)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3 1.5 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0045180 basal cortex(GO:0045180)
0.2 0.9 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.2 3.0 GO:0031005 filamin binding(GO:0031005)
0.3 2.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 1.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.4 1.3 GO:0009881 photoreceptor activity(GO:0009881)
0.0 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 1.0 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.2 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.2 0.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)