Motif ID: Rora

Z-value: 1.045


Transcription factors associated with Rora:

Gene SymbolEntrez IDGene Name
Rora ENSMUSG00000032238.11 Rora

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Roramm10_v2_chr9_+_68653761_686537860.373.2e-02Click!


Activity profile for motif Rora.

activity profile for motif Rora


Sorted Z-values histogram for motif Rora

Sorted Z-values for motif Rora



Network of associatons between targets according to the STRING database.



First level regulatory network of Rora

PNG image of the network

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Top targets:


Showing 1 to 20 of 194 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_79386943 12.150 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr15_-_66801577 8.271 ENSMUST00000168589.1
Sla
src-like adaptor
chr11_+_113619318 6.551 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr2_+_170731807 5.467 ENSMUST00000029075.4
Dok5
docking protein 5
chr5_+_37028329 5.264 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr17_-_43667015 4.979 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr14_+_64589802 4.729 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr1_+_32172711 4.611 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr8_+_71568866 4.588 ENSMUST00000034267.4
Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
chr19_-_46327121 4.116 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr1_+_159737510 4.068 ENSMUST00000111669.3
Tnr
tenascin R
chr5_-_106696819 4.009 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr7_+_45705088 3.908 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr2_+_178119166 3.872 ENSMUST00000108916.1
Phactr3
phosphatase and actin regulator 3
chr5_-_106696530 3.793 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr2_-_5676046 3.597 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr19_-_37207293 3.594 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr10_+_57794335 3.564 ENSMUST00000151623.1
ENSMUST00000020022.7
Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr5_+_19227046 3.511 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_178118975 3.505 ENSMUST00000108917.1
Phactr3
phosphatase and actin regulator 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.2 GO:0007601 visual perception(GO:0007601)
0.7 6.6 GO:0030432 peristalsis(GO:0030432)
1.9 5.8 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.6 5.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 5.3 GO:0050890 cognition(GO:0050890)
1.7 5.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
1.2 5.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.9 4.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.6 4.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.4 4.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
1.4 4.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 4.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 4.0 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
1.0 3.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.6 3.6 GO:1901524 regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.5 3.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.5 3.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.4 3.5 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.6 3.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 3.3 GO:0050770 regulation of axonogenesis(GO:0050770)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.9 GO:0044297 cell body(GO:0044297)
0.0 11.1 GO:0005768 endosome(GO:0005768)
0.0 9.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 8.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 7.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 7.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 7.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 6.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.9 6.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 5.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 4.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 4.6 GO:0005901 caveola(GO:0005901)
1.4 4.1 GO:0072534 perineuronal net(GO:0072534)
0.7 4.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 3.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.8 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.7 3.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 3.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 3.1 GO:0044292 dendrite terminus(GO:0044292)
0.1 3.0 GO:0043194 axon initial segment(GO:0043194)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 13.2 GO:0019841 retinol binding(GO:0019841)
0.4 7.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 6.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
2.2 6.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 6.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.6 6.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.4 5.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 4.7 GO:0005158 insulin receptor binding(GO:0005158)
0.2 4.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 4.6 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.5 4.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 4.1 GO:0046625 sphingolipid binding(GO:0046625)
0.1 4.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 4.0 GO:0050811 GABA receptor binding(GO:0050811)
0.6 3.8 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 3.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.3 3.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.6 3.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 3.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.6 3.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)