Motif ID: Rxra
Z-value: 0.958
Transcription factors associated with Rxra:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rxra | ENSMUSG00000015846.8 | Rxra |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rxra | mm10_v2_chr2_+_27677201_27677229 | -0.84 | 1.4e-09 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.4 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 1.4 | 5.5 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 1.0 | 3.1 | GO:0033364 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364) |
| 0.7 | 2.9 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.6 | 1.9 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.5 | 2.3 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.4 | 3.2 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.4 | 3.4 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.3 | 5.4 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.3 | 1.6 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.3 | 2.2 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.3 | 10.5 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.2 | 4.5 | GO:0010039 | response to iron ion(GO:0010039) |
| 0.2 | 2.4 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.2 | 0.6 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
| 0.2 | 0.9 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.2 | 2.5 | GO:0051205 | protein insertion into membrane(GO:0051205) |
| 0.2 | 0.6 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.1 | 3.9 | GO:0009409 | response to cold(GO:0009409) |
| 0.1 | 4.6 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.1 | 2.2 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.1 | 1.3 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.1 | 1.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 2.0 | GO:0051974 | negative regulation of telomerase activity(GO:0051974) |
| 0.1 | 2.1 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.1 | 0.3 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 0.1 | 2.3 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 0.4 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
| 0.1 | 0.2 | GO:0072008 | glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
| 0.1 | 0.9 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 1.1 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.1 | 2.2 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.1 | 0.2 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
| 0.1 | 0.1 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.1 | 0.4 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.0 | 0.9 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.0 | 0.1 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
| 0.0 | 3.1 | GO:0015807 | L-amino acid transport(GO:0015807) |
| 0.0 | 3.2 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 1.1 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 2.0 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.0 | 1.1 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 3.0 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.0 | 0.3 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.0 | 5.3 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.4 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.0 | 0.3 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.0 | 1.5 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.0 | 0.4 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.0 | 0.4 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.0 | 0.9 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.0 | 0.1 | GO:0046929 | negative regulation of neurotransmitter secretion(GO:0046929) |
| 0.0 | 0.7 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.8 | GO:0010508 | autophagosome assembly(GO:0000045) positive regulation of autophagy(GO:0010508) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 6.4 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.7 | 2.9 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.7 | 2.7 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.7 | 2.0 | GO:1990879 | CST complex(GO:1990879) |
| 0.4 | 2.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.4 | 3.4 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.4 | 4.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.3 | 2.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.3 | 1.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 0.8 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 0.9 | GO:0031314 | mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 0.4 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.1 | 1.8 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 5.5 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 4.5 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.1 | 2.8 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.1 | 1.5 | GO:0045120 | transcription factor TFIID complex(GO:0005669) pronucleus(GO:0045120) |
| 0.1 | 1.3 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.4 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 1.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 5.9 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.5 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 2.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 2.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 1.0 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 5.5 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.9 | 4.5 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.6 | 2.9 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.6 | 2.3 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.5 | 1.9 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.5 | 2.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.5 | 3.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.4 | 2.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.2 | 2.4 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.2 | 2.2 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.2 | 2.0 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.2 | 0.5 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.2 | 2.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.1 | 3.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 2.8 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 1.0 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.1 | 8.2 | GO:0061733 | peptide-lysine-N-acetyltransferase activity(GO:0061733) |
| 0.1 | 2.1 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 3.3 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 2.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 3.1 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.1 | 1.3 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 4.6 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.1 | 2.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 1.1 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
| 0.0 | 0.3 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 1.1 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.3 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 2.1 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.9 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 0.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.5 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 1.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.6 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.1 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.7 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.1 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.0 | 6.6 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 1.1 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 3.1 | GO:0003729 | mRNA binding(GO:0003729) |
| 0.0 | 4.0 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
| 0.0 | 1.8 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.6 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 2.4 | GO:0001664 | G-protein coupled receptor binding(GO:0001664) |
