Motif ID: Scrt1

Z-value: 2.117


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.853.3e-10Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_144939823 14.331 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr10_+_56377300 13.748 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr16_+_16213318 12.703 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
 Pkp2


plakophilin 2


chr4_-_134012381 12.247 ENSMUST00000176113.1
 Lin28a
lin-28 homolog A (C. elegans)
chr13_+_99100698 10.740 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr7_-_30973367 9.973 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr15_-_101054399 9.726 ENSMUST00000178140.1
 Fignl2
fidgetin-like 2
chr11_-_55419898 9.001 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr2_+_131234043 8.279 ENSMUST00000041362.5
ENSMUST00000110199.2
 Mavs

mitochondrial antiviral signaling protein

chr9_+_91368811 7.764 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr18_+_56432116 7.672 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr8_+_31187317 7.599 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
 Fut10



fucosyltransferase 10



chr7_-_30973399 7.568 ENSMUST00000098553.4
ENSMUST00000147431.1
 Lsr

lipolysis stimulated lipoprotein receptor

chr5_-_137611372 7.489 ENSMUST00000054564.6
 Pcolce
procollagen C-endopeptidase enhancer protein
chr12_-_40038025 7.350 ENSMUST00000101472.3
 Arl4a
ADP-ribosylation factor-like 4A
chr6_-_124779686 7.218 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
 Lrrc23



leucine rich repeat containing 23



chr14_-_70642268 7.036 ENSMUST00000022697.5
 Fgf17
fibroblast growth factor 17
chr15_-_98004634 6.885 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1

chr7_-_30973464 6.884 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor
chr6_+_138140521 6.860 ENSMUST00000120939.1
ENSMUST00000120302.1
 Mgst1

microsomal glutathione S-transferase 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.1 24.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.4 16.7 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
2.0 14.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.9 14.2 GO:0030953 astral microtubule organization(GO:0030953)
4.6 13.7 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.4 13.6 GO:0050873 brown fat cell differentiation(GO:0050873)
1.0 13.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
4.2 12.7 GO:0086069 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 12.7 GO:0008380 RNA splicing(GO:0008380)
1.7 10.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.4 9.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 9.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
1.1 8.9 GO:0048852 diencephalon morphogenesis(GO:0048852)
2.8 8.3 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.5 7.6 GO:0036065 fucosylation(GO:0036065)
0.0 7.3 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 7.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
1.7 6.9 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.7 6.9 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.5 6.8 GO:0035269 protein O-linked mannosylation(GO:0035269)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 26.7 GO:0005794 Golgi apparatus(GO:0005794)
4.1 24.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 20.2 GO:0031012 extracellular matrix(GO:0031012)
1.5 18.4 GO:0030057 desmosome(GO:0030057)
0.2 16.3 GO:0005604 basement membrane(GO:0005604)
0.2 15.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 14.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.4 13.7 GO:0005916 fascia adherens(GO:0005916)
0.1 13.6 GO:0031514 motile cilium(GO:0031514)
0.9 13.3 GO:0042555 MCM complex(GO:0042555)
0.0 12.7 GO:0005813 centrosome(GO:0005813)
0.2 12.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 11.7 GO:0005884 actin filament(GO:0005884)
0.1 11.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 11.5 GO:0030133 transport vesicle(GO:0030133)
2.3 9.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 7.3 GO:0005635 nuclear envelope(GO:0005635)
0.2 7.2 GO:0015030 Cajal body(GO:0015030)
0.1 7.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.5 6.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 28.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 24.0 GO:0003924 GTPase activity(GO:0003924)
0.9 18.0 GO:0035198 miRNA binding(GO:0035198)
0.2 14.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 14.5 GO:0016504 peptidase activator activity(GO:0016504)
0.6 14.3 GO:0070064 proline-rich region binding(GO:0070064)
2.7 13.7 GO:0071253 connexin binding(GO:0071253)
1.1 12.7 GO:0045294 alpha-catenin binding(GO:0045294)
2.3 11.6 GO:0032027 myosin light chain binding(GO:0032027)
0.7 10.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 9.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 9.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
2.1 8.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 8.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 7.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 7.7 GO:0005178 integrin binding(GO:0005178)
0.7 7.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 7.6 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) oligosaccharyl transferase activity(GO:0004576) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
2.3 7.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.5 6.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)