Motif ID: Scrt2

Z-value: 1.296


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.817.9e-09Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 113 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_56377300 10.847 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr16_+_16213318 8.772 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
 Pkp2


plakophilin 2


chr6_-_53820764 7.862 ENSMUST00000127748.2
 Tril
TLR4 interactor with leucine-rich repeats
chr2_-_164443177 5.588 ENSMUST00000017153.3
 Sdc4
syndecan 4
chr11_-_55419898 5.515 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr9_+_91368811 5.404 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr5_-_137611372 5.325 ENSMUST00000054564.6
 Pcolce
procollagen C-endopeptidase enhancer protein
chr4_-_134012381 5.144 ENSMUST00000176113.1
 Lin28a
lin-28 homolog A (C. elegans)
chr3_+_34649987 5.136 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr7_-_25250720 4.820 ENSMUST00000116343.2
ENSMUST00000045847.8
 Erf

Ets2 repressor factor

chr6_-_135168162 4.796 ENSMUST00000045855.7
 Hebp1
heme binding protein 1
chr9_+_91368970 4.770 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr5_-_137611429 4.713 ENSMUST00000031731.7
 Pcolce
procollagen C-endopeptidase enhancer protein
chr8_+_31187317 4.679 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
 Fut10



fucosyltransferase 10



chr7_-_30973399 4.631 ENSMUST00000098553.4
ENSMUST00000147431.1
 Lsr

lipolysis stimulated lipoprotein receptor

chr11_+_53770458 4.607 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
 Irf1



interferon regulatory factor 1



chr7_-_30973367 4.404 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr12_-_40037387 4.265 ENSMUST00000146905.1
 Arl4a
ADP-ribosylation factor-like 4A
chr3_-_53657339 4.264 ENSMUST00000091137.4
 Frem2
Fras1 related extracellular matrix protein 2
chr7_-_30973464 4.251 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 13.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
3.6 10.8 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
2.9 8.8 GO:0086069 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.3 8.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 7.9 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.3 5.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.1 5.6 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 5.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.7 5.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.6 5.1 GO:0010587 miRNA catabolic process(GO:0010587) positive regulation of cell proliferation involved in kidney development(GO:1901724)
1.0 4.8 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 4.8 GO:0042168 heme metabolic process(GO:0042168)
0.3 4.7 GO:0036065 fucosylation(GO:0036065)
1.5 4.6 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 4.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 4.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.7 4.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.8 4.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.6 4.0 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.4 3.9 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 13.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 12.3 GO:0031012 extracellular matrix(GO:0031012)
1.0 12.1 GO:0030057 desmosome(GO:0030057)
1.1 10.8 GO:0005916 fascia adherens(GO:0005916)
1.3 7.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 7.8 GO:0005604 basement membrane(GO:0005604)
0.0 7.5 GO:0098793 presynapse(GO:0098793)
0.2 6.2 GO:0043034 costamere(GO:0043034)
0.1 6.0 GO:0005581 collagen trimer(GO:0005581)
1.4 5.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 5.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 4.6 GO:0005925 focal adhesion(GO:0005925)
0.0 4.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.1 GO:0005759 mitochondrial matrix(GO:0005759)
1.0 4.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.0 4.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3 3.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 3.6 GO:0042555 MCM complex(GO:0042555)
0.0 3.5 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 15.6 GO:0005518 collagen binding(GO:0005518)
0.9 13.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
2.2 10.8 GO:0071253 connexin binding(GO:0071253)
0.2 10.7 GO:0030276 clathrin binding(GO:0030276)
0.5 10.3 GO:0035198 miRNA binding(GO:0035198)
0.1 10.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 9.0 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.7 8.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 8.8 GO:0003924 GTPase activity(GO:0003924)
0.6 7.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.4 5.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.1 5.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 5.0 GO:0051015 actin filament binding(GO:0051015)
0.1 4.8 GO:0020037 heme binding(GO:0020037)
0.0 4.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 4.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 4.4 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.1 4.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.8 4.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 4.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)