Motif ID: Sin3a

Z-value: 1.388


Transcription factors associated with Sin3a:

Gene SymbolEntrez IDGene Name
Sin3a ENSMUSG00000042557.8 Sin3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sin3amm10_v2_chr9_+_57072024_570720480.231.9e-01Click!


Activity profile for motif Sin3a.

activity profile for motif Sin3a


Sorted Z-values histogram for motif Sin3a

Sorted Z-values for motif Sin3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Sin3a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_69360294 8.105 ENSMUST00000033532.6
 Aff2
AF4/FMR2 family, member 2
chr1_-_56971762 5.217 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr11_-_69369377 4.718 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr1_-_56972437 4.089 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr15_-_78120011 4.073 ENSMUST00000019290.2
 Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr2_-_36105271 3.908 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr15_-_66286224 3.824 ENSMUST00000070256.7
 Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chrX_-_104201099 3.774 ENSMUST00000087879.4
 C77370
expressed sequence C77370
chrX_-_104201126 3.695 ENSMUST00000056502.6
ENSMUST00000118314.1
 C77370

expressed sequence C77370

chr12_-_5375682 3.622 ENSMUST00000020958.8
 Klhl29
kelch-like 29
chr1_-_72536930 3.568 ENSMUST00000047786.5
 March4
membrane-associated ring finger (C3HC4) 4
chr5_+_117413977 3.289 ENSMUST00000180430.1
 Ksr2
kinase suppressor of ras 2
chr1_+_167001457 3.201 ENSMUST00000126198.1
 Fam78b
family with sequence similarity 78, member B
chr7_+_36698002 2.861 ENSMUST00000021641.6
 Tshz3
teashirt zinc finger family member 3
chr10_-_43174521 2.786 ENSMUST00000040275.7
 Sobp
sine oculis-binding protein homolog (Drosophila)
chr1_+_167001417 2.782 ENSMUST00000165874.1
 Fam78b
family with sequence similarity 78, member B
chr4_+_54947976 2.712 ENSMUST00000098070.3
 Zfp462
zinc finger protein 462
chr6_-_39206782 2.692 ENSMUST00000002305.8
 Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_-_106458440 2.691 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr2_-_113217051 2.690 ENSMUST00000080673.5
 Ryr3
ryanodine receptor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 536 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 10.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 8.7 GO:0060081 membrane hyperpolarization(GO:0060081)
0.7 7.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 6.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.2 6.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
1.7 5.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 5.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 5.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 4.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.5 4.6 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.8 4.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.2 4.1 GO:0016082 synaptic vesicle priming(GO:0016082)
1.3 4.0 GO:0050975 sensory perception of touch(GO:0050975)
0.7 3.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 3.9 GO:0051297 centrosome organization(GO:0051297)
0.3 3.8 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 3.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 3.3 GO:0061038 uterus morphogenesis(GO:0061038)
0.3 3.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 3.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 208 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.0 GO:0060076 excitatory synapse(GO:0060076)
0.1 10.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 9.5 GO:0016607 nuclear speck(GO:0016607)
0.3 8.4 GO:0060077 inhibitory synapse(GO:0060077)
0.3 7.9 GO:0043194 axon initial segment(GO:0043194)
0.8 7.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 7.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.3 6.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 6.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 5.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 5.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 3.9 GO:0030673 axolemma(GO:0030673)
0.1 3.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 3.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 3.6 GO:0030426 growth cone(GO:0030426)
0.1 2.9 GO:0030118 clathrin coat(GO:0030118)
0.0 2.9 GO:0043195 terminal bouton(GO:0043195)
0.1 2.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 305 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.1 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.3 8.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.0 7.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 7.5 GO:0045296 cadherin binding(GO:0045296)
0.4 6.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 5.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 5.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.8 5.0 GO:0005042 netrin receptor activity(GO:0005042)
0.7 4.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 4.7 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 4.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 4.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 4.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.5 4.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 4.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
1.2 3.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 3.7 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.6 GO:0045182 translation regulator activity(GO:0045182)
0.4 3.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 3.5 GO:0004000 adenosine deaminase activity(GO:0004000)