Motif ID: Six6

Z-value: 0.527


Transcription factors associated with Six6:

Gene SymbolEntrez IDGene Name
Six6 ENSMUSG00000021099.5 Six6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Six6mm10_v2_chr12_+_72939724_729397580.531.4e-03Click!


Activity profile for motif Six6.

activity profile for motif Six6


Sorted Z-values histogram for motif Six6

Sorted Z-values for motif Six6



Network of associatons between targets according to the STRING database.



First level regulatory network of Six6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 167 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 4.905 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr9_-_114564315 3.401 ENSMUST00000111816.2
 Trim71
tripartite motif-containing 71
chr1_+_45311538 3.263 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr11_-_102365111 3.074 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr1_+_74713551 2.245 ENSMUST00000027356.5
 Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr18_+_56432116 2.232 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr7_+_46847128 2.138 ENSMUST00000005051.4
 Ldha
lactate dehydrogenase A
chr5_+_140607334 2.017 ENSMUST00000031555.1
 Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr14_+_67234620 1.948 ENSMUST00000176029.1
 Ebf2
early B cell factor 2
chrX_-_142966709 1.931 ENSMUST00000041317.2
 Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr4_+_134864536 1.889 ENSMUST00000030627.7
 Rhd
Rh blood group, D antigen
chr11_+_98412461 1.886 ENSMUST00000058295.5
 Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr13_+_43785107 1.655 ENSMUST00000015540.2
 Cd83
CD83 antigen
chr5_+_21543525 1.602 ENSMUST00000035651.4
 Lrrc17
leucine rich repeat containing 17
chr17_-_62606679 1.341 ENSMUST00000163332.1
 Efna5
ephrin A5
chr1_-_165708088 1.268 ENSMUST00000040357.8
ENSMUST00000097474.3
 Rcsd1

RCSD domain containing 1

chr10_+_24595623 1.236 ENSMUST00000176228.1
ENSMUST00000129142.1
 Ctgf

connective tissue growth factor

chr9_+_98422961 1.235 ENSMUST00000052068.9
 Rbp1
retinol binding protein 1, cellular
chr18_-_88927447 1.120 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chr12_+_52097737 1.103 ENSMUST00000040090.9
 Nubpl
nucleotide binding protein-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 3.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.7 3.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 3.1 GO:0046685 response to activity(GO:0014823) response to arsenic-containing substance(GO:0046685)
0.6 2.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.4 2.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.4 2.1 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.4 2.0 GO:0007386 compartment pattern specification(GO:0007386)
0.6 1.9 GO:0044849 estrous cycle(GO:0044849)
0.1 1.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.3 1.7 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.4 1.6 GO:0048539 bone marrow development(GO:0048539)
0.2 1.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 1.4 GO:0007338 single fertilization(GO:0007338)
0.0 1.4 GO:0032526 response to retinoic acid(GO:0032526)
0.4 1.3 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.2 1.3 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.2 1.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.3 1.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 3.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 3.1 GO:0014704 intercalated disc(GO:0014704)
0.0 2.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 2.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.9 GO:0043219 lateral loop(GO:0043219)
0.1 1.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0000776 kinetochore(GO:0000776)
0.1 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 0.7 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.0 GO:0030506 ankyrin binding(GO:0030506)
0.0 4.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 3.4 GO:0035198 miRNA binding(GO:0035198)
0.2 3.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.2 2.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 2.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.7 2.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 1.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 1.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.3 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.2 1.2 GO:0019841 retinol binding(GO:0019841)
0.1 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 1.1 GO:0047631 adenosine-diphosphatase activity(GO:0043262) ADP-ribose diphosphatase activity(GO:0047631)