Motif ID: Sox1

Z-value: 0.287


Transcription factors associated with Sox1:

Gene SymbolEntrez IDGene Name
Sox1 ENSMUSG00000096014.1 Sox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox1mm10_v2_chr8_+_12395287_123952950.593.4e-04Click!


Activity profile for motif Sox1.

activity profile for motif Sox1


Sorted Z-values histogram for motif Sox1

Sorted Z-values for motif Sox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_30923754 1.221 ENSMUST00000006697.8
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr14_-_30923547 1.201 ENSMUST00000170415.1
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr10_+_84756055 0.817 ENSMUST00000060397.6
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr17_+_34263209 0.779 ENSMUST00000040828.5
 H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr17_+_47737030 0.695 ENSMUST00000086932.3
 Tfeb
transcription factor EB
chr9_-_114390633 0.618 ENSMUST00000084881.4
 Crtap
cartilage associated protein
chr8_+_13159135 0.514 ENSMUST00000033824.6
 Lamp1
lysosomal-associated membrane protein 1
chr5_+_21186267 0.505 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr4_-_120747248 0.429 ENSMUST00000030376.7
 Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr17_-_34287770 0.420 ENSMUST00000174751.1
ENSMUST00000040655.6
 H2-Aa

histocompatibility 2, class II antigen A, alpha

chr5_-_140649018 0.380 ENSMUST00000042661.3
 Ttyh3
tweety homolog 3 (Drosophila)
chr15_-_75048837 0.357 ENSMUST00000179762.1
ENSMUST00000065408.9
 Ly6c1

lymphocyte antigen 6 complex, locus C1

chr9_-_108305941 0.266 ENSMUST00000044725.7
 Tcta
T cell leukemia translocation altered gene
chr7_+_119690026 0.209 ENSMUST00000047045.8
 Acsm4
acyl-CoA synthetase medium-chain family member 4
chr16_-_37654408 0.184 ENSMUST00000023514.3
 Ndufb4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr1_-_195131536 0.180 ENSMUST00000075451.6
 Cr1l
complement component (3b/4b) receptor 1-like
chr2_+_84798828 0.160 ENSMUST00000102642.2
ENSMUST00000150325.1
 Ube2l6

ubiquitin-conjugating enzyme E2L 6

chr7_+_67655414 0.115 ENSMUST00000107470.1
 Ttc23
tetratricopeptide repeat domain 23
chr3_-_34005490 0.113 ENSMUST00000060997.2
 Gm9791
predicted pseudogene 9791
chr15_-_74997634 0.108 ENSMUST00000023248.6
 Ly6a
lymphocyte antigen 6 complex, locus A
chr1_+_109983737 0.042 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2
chrX_+_74297097 0.036 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
 Atp6ap1



ATPase, H+ transporting, lysosomal accessory protein 1



chr2_-_84650760 0.036 ENSMUST00000111691.1
 Ctnnd1
catenin (cadherin associated protein), delta 1
chr2_-_84650714 0.013 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
 Ctnnd1



















catenin (cadherin associated protein), delta 1



















chr2_+_34406845 0.008 ENSMUST00000124443.1
ENSMUST00000113124.1
 Mapkap1

mitogen-activated protein kinase associated protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0002339 B cell selection(GO:0002339)
0.2 0.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.2 0.8 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.4 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 2.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.5 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.5 GO:0044194 cytolytic granule(GO:0044194)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)