Motif ID: Sox11

Z-value: 0.311


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.755.3e-07Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Showing 1 to 20 of 69 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_84064772 1.602 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr2_-_79456750 1.273 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chrX_+_166344692 0.948 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr5_+_14514918 0.897 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr9_-_16378231 0.885 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chrX_+_85574018 0.838 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr6_-_60829826 0.772 ENSMUST00000163779.1
Snca
synuclein, alpha
chr5_-_131616599 0.735 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr1_-_162866502 0.713 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr9_+_89909775 0.706 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr11_+_24080664 0.615 ENSMUST00000118955.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr4_+_21848039 0.598 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr11_+_69364010 0.572 ENSMUST00000166700.1
Gm17305
predicted gene, 17305
chr1_+_82233112 0.561 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chr13_-_99516537 0.516 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr8_-_34965631 0.503 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_+_107888129 0.494 ENSMUST00000035202.2
Mon1a
MON1 homolog A (yeast)
chr4_+_59003121 0.428 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr16_-_50330987 0.412 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr13_-_41487306 0.410 ENSMUST00000021794.6
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 1.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.9 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.7 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 0.5 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.0 0.5 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.9 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)