Motif ID: Sox11

Z-value: 0.311


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.755.3e-07Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_84064772 1.602 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr2_-_79456750 1.273 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chrX_+_166344692 0.948 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr5_+_14514918 0.897 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr9_-_16378231 0.885 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chrX_+_85574018 0.838 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr6_-_60829826 0.772 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr5_-_131616599 0.735 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr1_-_162866502 0.713 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr9_+_89909775 0.706 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr11_+_24080664 0.615 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr4_+_21848039 0.598 ENSMUST00000098238.2
ENSMUST00000108229.1
 Sfrs18

serine/arginine-rich splicing factor 18

chr11_+_69364010 0.572 ENSMUST00000166700.1
 Gm17305
predicted gene, 17305
chr1_+_82233112 0.561 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr13_-_99516537 0.516 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr8_-_34965631 0.503 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_+_107888129 0.494 ENSMUST00000035202.2
 Mon1a
MON1 homolog A (yeast)
chr4_+_59003121 0.428 ENSMUST00000095070.3
ENSMUST00000174664.1
 Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr16_-_50330987 0.412 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr13_-_41487306 0.410 ENSMUST00000021794.6
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr5_+_89027959 0.365 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr6_-_136173492 0.362 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr5_-_123141067 0.350 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr17_-_29007925 0.350 ENSMUST00000009138.5
ENSMUST00000119274.1
 Stk38

serine/threonine kinase 38

chr17_+_43016536 0.332 ENSMUST00000024708.4
 Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr2_-_36136773 0.323 ENSMUST00000028251.3
 Rbm18
RNA binding motif protein 18
chr7_-_73541738 0.320 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chrX_-_37104523 0.302 ENSMUST00000130324.1
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr12_+_8921598 0.287 ENSMUST00000020909.3
 Laptm4a
lysosomal-associated protein transmembrane 4A
chr4_-_44072578 0.281 ENSMUST00000173383.1
 Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr8_-_83442648 0.253 ENSMUST00000167525.1
 Scoc
short coiled-coil protein
chr11_-_69369377 0.244 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr16_+_8830093 0.225 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr8_+_85432686 0.224 ENSMUST00000180883.1
 1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr14_-_52213379 0.216 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr9_+_32116040 0.213 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr4_-_97584612 0.202 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_-_127792467 0.187 ENSMUST00000135091.1
 1500011K16Rik
RIKEN cDNA 1500011K16 gene
chr1_-_175491130 0.186 ENSMUST00000027812.5
 Rgs7
regulator of G protein signaling 7
chr12_-_54862783 0.171 ENSMUST00000078124.7
 Cfl2
cofilin 2, muscle
chr5_-_148552783 0.168 ENSMUST00000079324.7
ENSMUST00000164904.1
 Ubl3

ubiquitin-like 3

chr10_+_90576252 0.164 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
 Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr6_-_42693087 0.164 ENSMUST00000121083.1
 Fam115a
family with sequence similarity 115, member A
chr10_+_24869982 0.156 ENSMUST00000092646.6
 Med23
mediator complex subunit 23
chr9_+_101074727 0.151 ENSMUST00000085177.3
 Msl2
male-specific lethal 2 homolog (Drosophila)
chr19_+_8837676 0.150 ENSMUST00000159634.1
 Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr5_+_144100387 0.148 ENSMUST00000041804.7
 Lmtk2
lemur tyrosine kinase 2
chr4_-_97584605 0.137 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr16_-_38341812 0.131 ENSMUST00000114740.2
ENSMUST00000023501.8
 Maats1

MYCBP-associated, testis expressed 1

chr2_-_36136602 0.129 ENSMUST00000122456.1
 Rbm18
RNA binding motif protein 18
chr9_-_51102062 0.127 ENSMUST00000170947.1
 4833427G06Rik
RIKEN cDNA 4833427G06 gene
chr6_-_42693030 0.122 ENSMUST00000045140.4
 Fam115a
family with sequence similarity 115, member A
chr10_+_119992916 0.118 ENSMUST00000105261.2
 Grip1
glutamate receptor interacting protein 1
chr6_-_12109583 0.117 ENSMUST00000080891.5
 Gm6578
predicted gene 6578
chr5_+_89028035 0.116 ENSMUST00000113216.2
ENSMUST00000134303.1
 Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr19_-_46969474 0.110 ENSMUST00000086961.7
 Nt5c2
5'-nucleotidase, cytosolic II
chr5_+_64812336 0.101 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr10_-_14718191 0.091 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1
chr13_+_40859768 0.085 ENSMUST00000110191.2
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr7_-_55962466 0.076 ENSMUST00000032635.7
ENSMUST00000152649.1
 Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr8_+_105326354 0.067 ENSMUST00000015000.5
ENSMUST00000098453.2
 Tmem208

transmembrane protein 208

chr16_-_17911303 0.052 ENSMUST00000003621.8
 Dgcr14
DiGeorge syndrome critical region gene 14
chr4_-_129378116 0.042 ENSMUST00000030610.2
 Zbtb8a
zinc finger and BTB domain containing 8a
chr16_-_44016387 0.040 ENSMUST00000036174.3
 Gramd1c
GRAM domain containing 1C
chr2_-_86347764 0.038 ENSMUST00000099894.2
 Olfr1055
olfactory receptor 1055
chr11_+_4873951 0.036 ENSMUST00000038570.2
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr2_-_109278274 0.030 ENSMUST00000081631.3
 Mettl15
methyltransferase like 15
chr1_+_9848375 0.013 ENSMUST00000097826.4
 Sgk3
serum/glucocorticoid regulated kinase 3
chr10_-_76110956 0.010 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 1.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.5 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 0.9 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.7 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.5 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 0.9 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)