Motif ID: Sox13

Z-value: 0.320


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_133424404-0.382.8e-02Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 2.785 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr7_+_96210107 1.229 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr7_-_121035096 0.961 ENSMUST00000065740.2
 Gm9905
predicted gene 9905
chr1_+_19103022 0.889 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr18_+_69593361 0.888 ENSMUST00000114978.2
ENSMUST00000114977.1
 Tcf4

transcription factor 4

chr9_-_75597643 0.676 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr1_+_17145357 0.594 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr5_-_8367982 0.584 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
 Adam22






a disintegrin and metallopeptidase domain 22






chr13_-_66851513 0.541 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr19_-_19001099 0.525 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr18_+_64887690 0.503 ENSMUST00000163516.1
 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr8_-_11008458 0.498 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr1_-_93101825 0.391 ENSMUST00000112958.2
 Kif1a
kinesin family member 1A
chr13_-_66852017 0.369 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr1_+_135729147 0.354 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr18_+_37355271 0.350 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr15_-_50890396 0.239 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr3_+_60501252 0.219 ENSMUST00000099087.2
 Mbnl1
muscleblind-like 1 (Drosophila)
chr1_+_39900883 0.160 ENSMUST00000163854.2
ENSMUST00000168431.1
 Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

chr15_-_91049823 0.147 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
 Kif21a




kinesin family member 21A




chr4_+_103143052 0.138 ENSMUST00000106855.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr14_-_47568427 0.125 ENSMUST00000042988.6
 Atg14
autophagy related 14
chr3_-_141982224 0.110 ENSMUST00000029948.8
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr1_+_160906372 0.093 ENSMUST00000161609.1
 Rc3h1
RING CCCH (C3H) domains 1
chr10_-_116473418 0.083 ENSMUST00000087965.4
ENSMUST00000164271.1
 Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr16_-_28929658 0.079 ENSMUST00000100023.1
 Mb21d2
Mab-21 domain containing 2
chr6_-_56362356 0.067 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
 Pde1c



phosphodiesterase 1C



chr7_+_24271568 0.057 ENSMUST00000032696.6
 Zfp93
zinc finger protein 93
chr14_+_79515618 0.037 ENSMUST00000110835.1
 Elf1
E74-like factor 1
chr3_-_96058446 0.026 ENSMUST00000015891.5
 Vps45
vacuolar protein sorting 45 (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 2.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.5 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.1 0.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.5 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.9 GO:0030901 midbrain development(GO:0030901)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)