Motif ID: Sox14

Z-value: 1.126


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_99876193-0.241.8e-01Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_14523178 8.778 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr17_-_79355082 6.432 ENSMUST00000068958.7
 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr11_+_24076529 6.007 ENSMUST00000148087.1
 Gm12063
predicted gene 12063
chr11_+_67586520 5.978 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr8_-_84773381 5.685 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr7_-_19166119 5.420 ENSMUST00000094790.3
 Gipr
gastric inhibitory polypeptide receptor
chr18_-_43059418 5.074 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr11_+_67586675 4.622 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr7_+_96210107 4.593 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr18_-_43393346 4.028 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr4_+_13751297 3.922 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_58554799 3.632 ENSMUST00000098676.2
 Gm10657
predicted gene 10657
chr8_-_105289465 3.604 ENSMUST00000171788.1
ENSMUST00000014981.6
 4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr1_-_12991109 3.552 ENSMUST00000115403.2
ENSMUST00000115402.1
 Slco5a1

solute carrier organic anion transporter family, member 5A1

chr5_-_38159457 3.522 ENSMUST00000031009.4
 Nsg1
neuron specific gene family member 1
chr6_-_97617536 3.415 ENSMUST00000113355.2
 Frmd4b
FERM domain containing 4B
chr14_+_64589802 3.352 ENSMUST00000180610.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene
chr12_+_31265279 3.251 ENSMUST00000002979.8
ENSMUST00000170495.1
 Lamb1

laminin B1

chr7_-_29125142 3.200 ENSMUST00000179893.1
ENSMUST00000032813.9
 Ryr1

ryanodine receptor 1, skeletal muscle

chr10_-_79874233 3.123 ENSMUST00000166023.1
ENSMUST00000167707.1
ENSMUST00000165601.1
 BC005764


cDNA sequence BC005764



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.2 GO:0051017 actin filament bundle assembly(GO:0051017)
0.1 8.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.5 6.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 6.2 GO:0008340 determination of adult lifespan(GO:0008340)
1.5 6.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.9 5.8 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.4 5.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 5.4 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.7 5.1 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
1.1 4.6 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 4.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 4.3 GO:0030509 BMP signaling pathway(GO:0030509)
0.4 4.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 3.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 3.8 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.3 3.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.6 GO:0006342 chromatin silencing(GO:0006342)
0.2 3.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 3.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 3.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.5 GO:0005884 actin filament(GO:0005884)
0.0 10.8 GO:0015629 actin cytoskeleton(GO:0015629)
1.5 6.1 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 5.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 5.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.7 GO:0001726 ruffle(GO:0001726)
0.0 4.3 GO:0016607 nuclear speck(GO:0016607)
0.7 4.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 3.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 3.5 GO:0030027 lamellipodium(GO:0030027)
0.6 3.2 GO:0030314 junctional membrane complex(GO:0030314)
0.1 3.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 3.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.1 GO:0042641 actomyosin(GO:0042641)
0.3 2.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 2.8 GO:0070938 contractile ring(GO:0070938)
0.1 2.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 2.5 GO:0043034 costamere(GO:0043034)
0.2 2.3 GO:1990909 Wnt signalosome(GO:1990909)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 17.5 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.1 10.2 GO:0051015 actin filament binding(GO:0051015)
0.3 6.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 6.1 GO:0043208 glycosphingolipid binding(GO:0043208)
1.9 5.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 5.4 GO:0017046 peptide hormone binding(GO:0017046)
0.4 5.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 5.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.9 4.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 4.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 4.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
1.0 4.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 4.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 3.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 3.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.6 3.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 3.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.1 3.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 3.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.1 GO:0045295 gamma-catenin binding(GO:0045295)