Z-value: 1.591
Transcription factors associated with Spi1:
Activity-expression correlation:
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Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 763 entries
Log-likelihood per target Total log-likelihood Term Description
5.0
30.2
GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.4
23.0
GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.2
12.4
GO:2001214 positive regulation of vasculogenesis(GO:2001214)
3.6
10.9
GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
1.5
10.2
GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
1.0
9.0
GO:0051639 actin filament network formation(GO:0051639)
0.8
8.4
GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.7
8.1
GO:0050765 negative regulation of phagocytosis(GO:0050765)
1.3
7.9
GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
1.5
7.7
GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
1.9
7.6
GO:1903416 response to glycoside(GO:1903416)
0.7
7.4
GO:0033572 transferrin transport(GO:0033572)
0.4
7.2
GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.4
7.0
GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2
7.0
GO:0044380 protein localization to cytoskeleton(GO:0044380)
1.7
6.9
GO:0032439 endosome localization(GO:0032439)
1.7
6.9
GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.8
6.7
GO:0015669 gas transport(GO:0015669) carbon dioxide transport(GO:0015670)
1.3
6.4
GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
1.0
6.3
GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 313 entries
Log-likelihood per target Total log-likelihood Term Description
0.2
61.3
GO:0005667 transcription factor complex(GO:0005667)
0.0
24.3
GO:1903561 extracellular vesicle(GO:1903561)
0.4
19.6
GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0
13.3
GO:0005730 nucleolus(GO:0005730)
0.2
11.1
GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.2
10.4
GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.5
9.8
GO:0016327 apicolateral plasma membrane(GO:0016327)
2.2
9.0
GO:0032127 dense core granule membrane(GO:0032127)
0.1
9.0
GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.8
8.9
GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.1
8.8
GO:0005833 hemoglobin complex(GO:0005833)
0.1
8.5
GO:0005581 collagen trimer(GO:0005581)
0.8
8.3
GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2
8.3
GO:0015030 Cajal body(GO:0015030)
0.1
8.0
GO:0031012 extracellular matrix(GO:0031012)
0.2
7.9
GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1
7.9
GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
1.3
7.6
GO:0045179 apical cortex(GO:0045179)
0.5
7.4
GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.7
7.3
GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 455 entries
Log-likelihood per target Total log-likelihood Term Description
0.2
38.3
GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1
34.6
GO:0003779 actin binding(GO:0003779)
0.4
20.6
GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
1.2
20.5
GO:0017166 vinculin binding(GO:0017166)
0.2
16.4
GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1
15.6
GO:0003735 structural constituent of ribosome(GO:0003735)
0.6
12.5
GO:0070410 co-SMAD binding(GO:0070410)
0.2
11.8
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2
10.9
GO:0000049 tRNA binding(GO:0000049)
0.2
10.8
GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0
9.8
GO:0005525 GTP binding(GO:0005525)
0.3
9.5
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.7
8.9
GO:0008301 DNA binding, bending(GO:0008301)
0.1
8.6
GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2
8.4
GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0
8.4
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0
7.9
GO:0008134 transcription factor binding(GO:0008134)
1.5
7.5
GO:0042610 CD8 receptor binding(GO:0042610)
0.2
7.5
GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1
7.5
GO:0008013 beta-catenin binding(GO:0008013)
