Motif ID: Spib

Z-value: 0.770


Transcription factors associated with Spib:

Gene SymbolEntrez IDGene Name
Spib ENSMUSG00000008193.7 Spib



Activity profile for motif Spib.

activity profile for motif Spib


Sorted Z-values histogram for motif Spib

Sorted Z-values for motif Spib



Network of associatons between targets according to the STRING database.



First level regulatory network of Spib

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66812593 3.552 ENSMUST00000100572.3
 Sla
src-like adaptor
chr6_-_23248264 1.808 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr17_+_93199348 1.782 ENSMUST00000064775.6
 Adcyap1
adenylate cyclase activating polypeptide 1
chr2_+_121357714 1.619 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
 Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr6_+_137410721 1.475 ENSMUST00000167002.1
 Ptpro
protein tyrosine phosphatase, receptor type, O
chr5_+_149265035 1.324 ENSMUST00000130144.1
ENSMUST00000071130.3
 Alox5ap

arachidonate 5-lipoxygenase activating protein

chr7_-_126704736 1.293 ENSMUST00000131415.1
 Coro1a
coronin, actin binding protein 1A
chr2_+_32721055 1.206 ENSMUST00000074248.4
 Sh2d3c
SH2 domain containing 3C
chr2_+_121358591 1.192 ENSMUST00000000317.6
ENSMUST00000129130.1
 Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chrX_-_43167817 1.178 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr4_+_118409331 1.172 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr2_-_52558539 1.166 ENSMUST00000102760.3
ENSMUST00000102761.2
 Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr7_-_126704179 1.123 ENSMUST00000106364.1
 Coro1a
coronin, actin binding protein 1A
chr7_-_126704522 1.086 ENSMUST00000135087.1
 Coro1a
coronin, actin binding protein 1A
chr3_-_123672321 1.026 ENSMUST00000172537.1
ENSMUST00000029602.6
 Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr10_-_6980376 1.019 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr19_+_12846773 0.974 ENSMUST00000164001.1
 Gm5244
predicted pseudogene 5244
chr5_+_81021202 0.952 ENSMUST00000117253.1
ENSMUST00000120128.1
 Lphn3

latrophilin 3

chr6_-_136941694 0.941 ENSMUST00000032344.5
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr12_+_33957645 0.939 ENSMUST00000049089.5
 Twist1
twist basic helix-loop-helix transcription factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.5 GO:0032796 uropod organization(GO:0032796)
0.0 2.9 GO:0032091 negative regulation of protein binding(GO:0032091)
0.6 1.8 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.3 1.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 1.5 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 1.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 1.3 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.1 1.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.2 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 1.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.3 1.0 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 1.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 0.9 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 0.9 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.2 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.8 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.8 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.4 GO:0043209 myelin sheath(GO:0043209)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.8 GO:0043195 terminal bouton(GO:0043195)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.3 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.2 GO:0071439 clathrin complex(GO:0071439)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.0 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.1 0.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 2.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.7 2.8 GO:0004111 creatine kinase activity(GO:0004111)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.2 1.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 1.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)