Motif ID: Stat2

Z-value: 2.826


Transcription factors associated with Stat2:

Gene SymbolEntrez IDGene Name
Stat2 ENSMUSG00000040033.9 Stat2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat2mm10_v2_chr10_+_128270546_1282705770.754.5e-07Click!


Activity profile for motif Stat2.

activity profile for motif Stat2


Sorted Z-values histogram for motif Stat2

Sorted Z-values for motif Stat2



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_103434211 26.057 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
 Ifi27





interferon, alpha-inducible protein 27





chr6_+_90550789 23.858 ENSMUST00000130418.1
ENSMUST00000032175.8
 Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr7_-_141010759 23.432 ENSMUST00000026565.6
 Ifitm3
interferon induced transmembrane protein 3
chr16_+_23609895 15.822 ENSMUST00000038423.5
 Rtp4
receptor transporter protein 4
chr16_+_26581704 15.532 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
 Il1rap



interleukin 1 receptor accessory protein



chr8_-_84773381 12.008 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr3_+_81932601 11.935 ENSMUST00000029649.2
 Ctso
cathepsin O
chr2_-_51972990 11.334 ENSMUST00000145481.1
ENSMUST00000112705.2
 Nmi

N-myc (and STAT) interactor

chr1_-_173942445 11.286 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chrX_+_166238901 10.196 ENSMUST00000112235.1
 Gpm6b
glycoprotein m6b
chr6_-_39118211 9.690 ENSMUST00000038398.6
 Parp12
poly (ADP-ribose) polymerase family, member 12
chr15_-_66812593 9.546 ENSMUST00000100572.3
 Sla
src-like adaptor
chr10_-_94944578 9.253 ENSMUST00000099337.3
 Plxnc1
plexin C1
chr1_+_153751946 9.050 ENSMUST00000183241.1
 Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr18_+_61045139 8.868 ENSMUST00000025522.4
ENSMUST00000115274.1
 Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr1_-_170110491 8.672 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr18_-_39489776 8.658 ENSMUST00000025300.6
 Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr1_+_153751859 8.586 ENSMUST00000182538.1
 Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr16_+_42907563 8.575 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr11_+_88999376 8.460 ENSMUST00000100627.2
ENSMUST00000107896.3
ENSMUST00000000284.6
 Trim25


tripartite motif-containing 25



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 30.8 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
1.5 27.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.9 25.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
4.9 24.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
8.0 23.9 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.5 22.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
5.3 15.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 15.6 GO:0001919 regulation of receptor recycling(GO:0001919)
1.9 15.5 GO:0072602 interleukin-4 secretion(GO:0072602)
0.9 12.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
3.8 11.3 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
1.6 11.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.8 11.1 GO:0044565 dendritic cell proliferation(GO:0044565)
1.5 10.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.7 9.9 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.9 9.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.4 9.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.9 9.0 GO:0042118 endothelial cell activation(GO:0042118)
3.0 8.9 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
2.9 8.8 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 80.3 GO:0016021 integral component of membrane(GO:0016021)
0.1 64.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.3 31.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 26.3 GO:0005739 mitochondrion(GO:0005739)
0.6 26.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 24.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.4 15.6 GO:0043083 synaptic cleft(GO:0043083)
0.9 9.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.2 9.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.8 9.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 8.8 GO:0032587 ruffle membrane(GO:0032587)
1.2 8.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 7.9 GO:0005829 cytosol(GO:0005829)
2.5 7.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 7.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 6.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 5.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 5.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 5.1 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 30.8 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.2 30.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.1 26.1 GO:0005521 lamin binding(GO:0005521)
6.1 24.4 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 24.3 GO:0005525 GTP binding(GO:0005525)
8.0 23.9 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 18.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
2.2 15.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.2 15.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 13.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.7 13.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 11.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 10.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.7 9.3 GO:0017154 semaphorin receptor activity(GO:0017154)
1.8 8.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 8.8 GO:0070412 R-SMAD binding(GO:0070412)
1.0 8.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.7 8.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 8.4 GO:0003729 mRNA binding(GO:0003729)
0.4 8.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)