Motif ID: Stat5a

Z-value: 1.494


Transcription factors associated with Stat5a:

Gene SymbolEntrez IDGene Name
Stat5a ENSMUSG00000004043.8 Stat5a



Activity profile for motif Stat5a.

activity profile for motif Stat5a


Sorted Z-values histogram for motif Stat5a

Sorted Z-values for motif Stat5a



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat5a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 6.655 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr10_-_42583628 6.225 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr7_+_107567445 5.432 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr9_+_92250039 5.187 ENSMUST00000093801.3
 Plscr1
phospholipid scramblase 1
chr3_+_19957037 5.021 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
 Cp


ceruloplasmin


chr6_+_4755327 4.773 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr2_-_168767136 4.724 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr9_-_114564315 4.673 ENSMUST00000111816.2
 Trim71
tripartite motif-containing 71
chr2_-_80447625 4.625 ENSMUST00000028389.3
 Frzb
frizzled-related protein
chr9_-_79977782 4.526 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr6_+_138141569 4.523 ENSMUST00000118091.1
 Mgst1
microsomal glutathione S-transferase 1
chr7_+_88278085 4.483 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr2_+_5845243 4.357 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr11_+_69964758 4.261 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
 Cldn7


claudin 7


chr14_-_48665098 4.215 ENSMUST00000118578.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr15_-_103366763 3.983 ENSMUST00000023128.6
 Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr11_-_102365111 3.963 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr16_+_33829624 3.886 ENSMUST00000115028.3
 Itgb5
integrin beta 5
chr10_+_22158566 3.832 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr11_-_55419898 3.822 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 487 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 9.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.5 9.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.9 9.1 GO:0097421 liver regeneration(GO:0097421)
0.4 8.1 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.5 7.5 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
1.8 7.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.4 7.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 6.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.3 6.7 GO:0015671 oxygen transport(GO:0015671)
0.1 6.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
1.1 5.7 GO:0021764 amygdala development(GO:0021764)
0.2 5.7 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.3 5.5 GO:0046688 response to copper ion(GO:0046688)
0.6 5.4 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.7 5.2 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
1.3 5.1 GO:0046061 dATP catabolic process(GO:0046061)
0.1 5.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
1.5 4.6 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
1.1 4.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.6 4.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638) positive regulation of lamellipodium morphogenesis(GO:2000394)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 211 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 20.9 GO:0005615 extracellular space(GO:0005615)
0.2 15.6 GO:0072562 blood microparticle(GO:0072562)
0.1 15.5 GO:0031012 extracellular matrix(GO:0031012)
0.3 14.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 14.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.5 9.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 7.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 7.2 GO:0005581 collagen trimer(GO:0005581)
0.1 7.2 GO:0015934 large ribosomal subunit(GO:0015934)
1.8 7.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6 6.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.8 6.7 GO:0005833 hemoglobin complex(GO:0005833)
1.2 6.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 5.2 GO:0000791 euchromatin(GO:0000791)
0.0 4.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.4 GO:0005901 caveola(GO:0005901)
0.2 4.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 4.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 4.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 4.0 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 329 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.3 GO:0005178 integrin binding(GO:0005178)
0.2 8.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 8.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.3 7.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 7.4 GO:0046977 TAP binding(GO:0046977)
0.9 7.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.8 7.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 7.1 GO:0005198 structural molecule activity(GO:0005198)
0.1 7.0 GO:0008201 heparin binding(GO:0008201)
1.7 6.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 6.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.2 6.6 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.4 6.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 5.2 GO:0042609 CD4 receptor binding(GO:0042609)
1.0 5.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 4.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 4.8 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
1.1 4.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 4.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 4.4 GO:0004601 peroxidase activity(GO:0004601)