Motif ID: Tal1

Z-value: 0.895


Transcription factors associated with Tal1:

Gene SymbolEntrez IDGene Name
Tal1 ENSMUSG00000028717.6 Tal1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tal1mm10_v2_chr4_+_115059507_1150595530.911.0e-13Click!


Activity profile for motif Tal1.

activity profile for motif Tal1


Sorted Z-values histogram for motif Tal1

Sorted Z-values for motif Tal1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tal1

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 26.015 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr11_+_32276400 21.543 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 20.266 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr10_+_97565436 9.377 ENSMUST00000038160.4
 Lum
lumican
chr7_-_99238564 6.495 ENSMUST00000064231.7
 Mogat2
monoacylglycerol O-acyltransferase 2
chr15_-_103251465 5.988 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
 Nfe2




nuclear factor, erythroid derived 2




chr17_+_36869567 5.127 ENSMUST00000060524.9
 Trim10
tripartite motif-containing 10
chr8_+_80494032 4.762 ENSMUST00000063359.6
 Gypa
glycophorin A
chr3_+_89136572 4.510 ENSMUST00000107482.3
ENSMUST00000127058.1
 Pklr

pyruvate kinase liver and red blood cell

chr3_+_89136133 4.391 ENSMUST00000047111.6
 Pklr
pyruvate kinase liver and red blood cell
chr8_-_77517898 4.246 ENSMUST00000076316.4
 Arhgap10
Rho GTPase activating protein 10
chr2_-_153241402 3.735 ENSMUST00000056924.7
 Plagl2
pleiomorphic adenoma gene-like 2
chr17_+_40811089 3.726 ENSMUST00000024721.7
 Rhag
Rhesus blood group-associated A glycoprotein
chr4_+_134864536 3.532 ENSMUST00000030627.7
 Rhd
Rh blood group, D antigen
chr6_-_72235559 3.531 ENSMUST00000042646.7
 Atoh8
atonal homolog 8 (Drosophila)
chr9_-_32541589 3.496 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr19_+_20601958 3.469 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr11_+_94936224 3.411 ENSMUST00000001547.7
 Col1a1
collagen, type I, alpha 1
chr2_+_84839395 3.317 ENSMUST00000146816.1
ENSMUST00000028469.7
 Slc43a1

solute carrier family 43, member 1

chr4_-_59438633 3.289 ENSMUST00000040166.7
ENSMUST00000107544.1
 Susd1

sushi domain containing 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
13.6 67.8 GO:0015671 oxygen transport(GO:0015671)
2.4 9.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.5 8.9 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.6 8.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 7.4 GO:0016126 sterol biosynthetic process(GO:0016126)
0.7 6.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.6 6.0 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
1.7 5.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 5.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
1.0 4.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.8 4.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 3.7 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.9 3.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 3.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.5 3.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 3.3 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.1 3.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 2.8 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.4 2.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 2.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.5 67.8 GO:0005833 hemoglobin complex(GO:0005833)
0.9 9.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 4.7 GO:0009897 external side of plasma membrane(GO:0009897)
1.1 3.4 GO:0005584 collagen type I trimer(GO:0005584)
0.0 3.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.7 GO:0005604 basement membrane(GO:0005604)
0.0 2.7 GO:0005814 centriole(GO:0005814)
0.2 2.5 GO:0045180 basal cortex(GO:0045180)
0.3 2.3 GO:0070187 telosome(GO:0070187)
0.5 2.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.4 1.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.3 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
13.6 67.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 10.0 GO:0005518 collagen binding(GO:0005518)
3.0 8.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 8.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
2.1 6.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 6.0 GO:0050699 WW domain binding(GO:0050699)
1.7 5.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.6 5.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 4.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 3.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.6 3.5 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 3.5 GO:0070888 E-box binding(GO:0070888)
0.0 3.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2 3.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 3.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 2.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.6 GO:0003924 GTPase activity(GO:0003924)
0.8 2.3 GO:0005534 galactose binding(GO:0005534)
0.6 2.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 2.3 GO:0001540 beta-amyloid binding(GO:0001540)