Motif ID: Tbp

Z-value: 2.305


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_15499960-0.575.3e-04Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 18.690 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr7_-_103853199 18.666 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr7_-_103843154 10.094 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr1_-_138842429 9.521 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr11_+_94936224 7.831 ENSMUST00000001547.7
 Col1a1
collagen, type I, alpha 1
chr1_-_171196229 7.618 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr7_-_142899985 7.277 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr13_+_23763660 6.642 ENSMUST00000055770.1
 Hist1h1a
histone cluster 1, H1a
chr17_+_24720063 6.378 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
 Rps2


ribosomal protein S2


chr7_-_137314394 5.458 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr11_+_120949053 5.391 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
 Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr13_-_21780616 5.338 ENSMUST00000080511.2
 Hist1h1b
histone cluster 1, H1b
chr1_+_109993982 5.287 ENSMUST00000027542.6
 Cdh7
cadherin 7, type 2
chr2_-_164857542 5.234 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr13_+_21717626 5.009 ENSMUST00000091754.2
 Hist1h3h
histone cluster 1, H3h
chr17_-_34000257 4.800 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
 H2-K1




histocompatibility 2, K1, K region




chr6_+_4747306 4.749 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
 Peg10


paternally expressed 10


chr19_-_53589067 4.714 ENSMUST00000095978.3
 Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr13_-_99900645 4.692 ENSMUST00000022150.6
 Cartpt
CART prepropeptide
chr6_-_125165707 4.601 ENSMUST00000118875.1
 Gapdh
glyceraldehyde-3-phosphate dehydrogenase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.8 28.8 GO:0015671 oxygen transport(GO:0015671)
0.9 27.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 19.9 GO:0006334 nucleosome assembly(GO:0006334)
1.4 18.7 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
0.6 10.4 GO:0019430 removal of superoxide radicals(GO:0019430)
1.9 9.5 GO:0035262 gonad morphogenesis(GO:0035262)
2.3 9.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.1 7.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.8 7.3 GO:0042414 epinephrine metabolic process(GO:0042414)
1.6 6.5 GO:0006407 rRNA export from nucleus(GO:0006407)
0.5 6.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.8 6.1 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.9 5.7 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.3 5.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 5.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.5 5.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
1.3 5.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 5.0 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.8 4.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.2 4.8 GO:0071353 cellular response to interleukin-4(GO:0071353)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 52.6 GO:0000786 nucleosome(GO:0000786)
3.6 29.1 GO:0005833 hemoglobin complex(GO:0005833)
0.4 17.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 12.4 GO:0043209 myelin sheath(GO:0043209)
0.4 11.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 9.1 GO:0031965 nuclear membrane(GO:0031965)
1.2 8.7 GO:0097452 GAIT complex(GO:0097452)
2.6 7.8 GO:0005584 collagen type I trimer(GO:0005584)
0.3 7.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 7.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.9 5.7 GO:0097512 cardiac myofibril(GO:0097512)
0.1 5.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 5.5 GO:0005871 kinesin complex(GO:0005871)
0.2 5.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 5.1 GO:0000776 kinetochore(GO:0000776)
0.4 4.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 4.6 GO:0005882 intermediate filament(GO:0005882)
0.1 4.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 4.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.6 3.8 GO:0032299 ribonuclease H2 complex(GO:0032299)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 34.5 GO:0042393 histone binding(GO:0042393)
7.3 29.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
3.1 18.7 GO:0019841 retinol binding(GO:0019841)
0.1 16.6 GO:0003735 structural constituent of ribosome(GO:0003735)
1.2 14.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 9.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.9 8.7 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.5 7.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.2 7.3 GO:0035240 dopamine binding(GO:0035240)
0.2 6.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 5.7 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 5.5 GO:0003777 microtubule motor activity(GO:0003777)
0.3 5.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 4.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 4.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 4.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 4.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 3.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.9 3.7 GO:0019808 polyamine binding(GO:0019808)