Motif ID: Tbr1

Z-value: 1.198


Transcription factors associated with Tbr1:

Gene SymbolEntrez IDGene Name
Tbr1 ENSMUSG00000035033.9 Tbr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbr1mm10_v2_chr2_+_61804453_61804538-0.672.4e-05Click!


Activity profile for motif Tbr1.

activity profile for motif Tbr1


Sorted Z-values histogram for motif Tbr1

Sorted Z-values for motif Tbr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbr1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_120899067 6.364 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr17_+_34263209 6.028 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chrX_+_96455359 5.135 ENSMUST00000033553.7
Heph
hephaestin
chr12_+_109459843 5.004 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr9_-_43239816 4.842 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr13_+_56609516 4.651 ENSMUST00000045173.8
Tgfbi
transforming growth factor, beta induced
chr6_+_4504814 4.553 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr1_+_12692430 4.244 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr7_-_144939823 4.206 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr6_-_94700137 4.168 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr17_+_87635974 4.072 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr11_+_32283511 3.970 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr8_+_45885479 3.914 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr11_+_32296489 3.908 ENSMUST00000093207.3
Hba-a2
hemoglobin alpha, adult chain 2
chr9_-_106199253 3.314 ENSMUST00000140761.1
Ppm1m
protein phosphatase 1M
chr4_+_117849193 3.076 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr10_+_26229707 3.073 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr4_+_117849361 3.058 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_-_157925056 2.954 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr4_-_34730157 2.900 ENSMUST00000108136.1
ENSMUST00000137514.1
ENSMUST00000029971.5
1700003M02Rik


RIKEN cDNA 1700003M02 gene



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 327 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 6.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.5 6.0 GO:0002339 B cell selection(GO:0002339)
1.0 5.1 GO:0030091 protein repair(GO:0030091)
0.2 5.1 GO:0006825 copper ion transport(GO:0006825)
0.1 5.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 5.0 GO:0035690 cellular response to drug(GO:0035690)
1.1 4.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.9 4.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 4.5 GO:0043589 skin morphogenesis(GO:0043589)
0.7 4.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 4.4 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
1.4 4.3 GO:1903232 melanosome assembly(GO:1903232)
1.4 4.2 GO:0032474 otolith morphogenesis(GO:0032474)
1.1 4.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.6 4.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.6 3.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 3.5 GO:0048821 erythrocyte development(GO:0048821)
0.1 3.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 3.3 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 3.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 150 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 9.0 GO:0005667 transcription factor complex(GO:0005667)
2.0 7.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 7.2 GO:0016324 apical plasma membrane(GO:0016324)
0.1 6.3 GO:0005604 basement membrane(GO:0005604)
0.9 6.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 5.5 GO:0043209 myelin sheath(GO:0043209)
0.0 5.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 5.3 GO:0005925 focal adhesion(GO:0005925)
0.1 5.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 4.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.8 GO:0001750 photoreceptor outer segment(GO:0001750)
1.5 4.6 GO:0005584 collagen type I trimer(GO:0005584)
0.2 4.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 4.4 GO:0005915 zonula adherens(GO:0005915)
0.3 4.4 GO:0035686 sperm fibrous sheath(GO:0035686)
1.4 4.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 3.8 GO:0005871 kinesin complex(GO:0005871)
0.1 3.4 GO:0001772 immunological synapse(GO:0001772)
0.0 3.4 GO:0015934 large ribosomal subunit(GO:0015934)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 224 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 13.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 9.9 GO:0050840 extracellular matrix binding(GO:0050840)
2.0 7.9 GO:0031720 haptoglobin binding(GO:0031720)
0.9 7.7 GO:0015643 toxic substance binding(GO:0015643)
1.2 7.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.9 6.4 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
1.0 5.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 5.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.9 4.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 4.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 4.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.4 4.4 GO:0070097 delta-catenin binding(GO:0070097)
1.4 4.3 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 4.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 4.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.5 4.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 4.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 3.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.8 3.8 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 3.8 GO:0048487 beta-tubulin binding(GO:0048487)