Motif ID: Tbx15

Z-value: 0.927


Transcription factors associated with Tbx15:

Gene SymbolEntrez IDGene Name
Tbx15 ENSMUSG00000027868.5 Tbx15



Activity profile for motif Tbx15.

activity profile for motif Tbx15


Sorted Z-values histogram for motif Tbx15

Sorted Z-values for motif Tbx15



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_129121889 8.197 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
 Hpca


hippocalcin


chr4_+_48045144 7.298 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr3_+_75557530 6.795 ENSMUST00000161776.1
ENSMUST00000029423.8
 Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr6_+_115134899 6.321 ENSMUST00000009538.5
ENSMUST00000169345.1
 Syn2

synapsin II

chr4_-_82505749 5.817 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr3_+_96181151 4.807 ENSMUST00000035371.8
 Sv2a
synaptic vesicle glycoprotein 2 a
chrX_+_7919816 4.785 ENSMUST00000041096.3
 Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr12_-_78980758 4.651 ENSMUST00000174072.1
 Tmem229b
transmembrane protein 229B
chr12_+_88953399 4.634 ENSMUST00000057634.7
 Nrxn3
neurexin III
chr14_-_55116935 4.526 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr5_-_84417359 3.902 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr17_-_81649607 3.768 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
 Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr8_+_84723003 3.495 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chr18_-_42899294 3.479 ENSMUST00000117687.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr7_+_25306085 3.418 ENSMUST00000119703.1
ENSMUST00000108409.1
 Tmem145

transmembrane protein 145

chr3_-_82074639 3.390 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr3_+_55461758 3.388 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr19_-_37207293 3.348 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
 Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr7_+_130936172 3.312 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr7_+_46396439 3.290 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 164 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.7 11.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0 7.7 GO:0006836 neurotransmitter transport(GO:0006836)
2.4 7.3 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.9 6.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 6.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
2.0 5.9 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.5 5.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 5.7 GO:0002021 response to dietary excess(GO:0002021)
1.4 4.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 4.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.3 4.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 4.1 GO:0001919 regulation of receptor recycling(GO:0001919)
1.0 3.9 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.4 3.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
1.3 3.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 3.8 GO:0035904 aorta development(GO:0035904)
0.1 3.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.5 3.5 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.7 3.4 GO:0019236 response to pheromone(GO:0019236)
0.2 3.4 GO:0006182 cGMP biosynthetic process(GO:0006182)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 11.2 GO:0044327 dendritic spine head(GO:0044327)
0.2 10.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 7.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 7.5 GO:0030673 axolemma(GO:0030673)
0.1 6.7 GO:0030315 T-tubule(GO:0030315)
0.0 5.9 GO:0030426 growth cone(GO:0030426)
0.6 5.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 5.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.9 4.5 GO:0030314 junctional membrane complex(GO:0030314)
0.0 4.5 GO:0030141 secretory granule(GO:0030141)
0.4 4.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 4.2 GO:0005814 centriole(GO:0005814)
0.0 4.0 GO:0030175 filopodium(GO:0030175)
0.1 3.9 GO:0042734 presynaptic membrane(GO:0042734)
0.3 3.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 3.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 3.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 3.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 8.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 8.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.4 7.5 GO:0030275 LRR domain binding(GO:0030275)
1.0 7.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.9 7.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 5.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 5.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 5.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 4.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 4.6 GO:0005246 calcium channel regulator activity(GO:0005246)
1.4 4.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.4 4.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 4.3 GO:0030674 protein binding, bridging(GO:0030674)
0.9 3.7 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 3.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 3.6 GO:0030276 clathrin binding(GO:0030276)
0.2 3.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
1.0 3.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.6 3.1 GO:0097001 ceramide binding(GO:0097001)
1.0 3.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)