Motif ID: Tbx1_Eomes

Z-value: 0.650

Transcription factors associated with Tbx1_Eomes:

Gene SymbolEntrez IDGene Name
Eomes ENSMUSG00000032446.8 Eomes
Tbx1 ENSMUSG00000009097.9 Tbx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Eomesmm10_v2_chr9_+_118478344_1184784510.154.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx1_Eomes

PNG image of the network

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Top targets:


Showing 1 to 20 of 160 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_13011747 4.373 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr1_-_138847579 3.141 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr17_+_29093763 2.000 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr4_+_125490688 1.998 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr10_+_26229707 1.924 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr10_+_4710119 1.842 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr7_-_100658394 1.835 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr7_+_18884679 1.724 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr6_-_24956106 1.687 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr7_-_28302238 1.646 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr7_-_100658364 1.590 ENSMUST00000107043.1
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr4_+_117849361 1.530 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr12_-_31634592 1.492 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chr4_+_84884418 1.449 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chrX_+_101383726 1.433 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr4_+_84884276 1.382 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chrX_+_100729917 1.358 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chrX_+_100730178 1.351 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr6_+_7555053 1.297 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr4_+_117849193 1.266 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9


Gene overrepresentation in biological_process category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0050807 regulation of synapse organization(GO:0050807)
0.6 3.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.9 2.8 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 2.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 2.7 GO:0090527 actin filament reorganization(GO:0090527)
0.2 2.0 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.2 2.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.5 1.8 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.3 1.7 GO:0098543 detection of bacterium(GO:0016045) negative regulation of natural killer cell activation(GO:0032815) detection of other organism(GO:0098543)
0.3 1.6 GO:0007386 compartment pattern specification(GO:0007386)
0.2 1.6 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.5 1.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 1.3 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.4 1.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 1.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.3 1.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0005581 collagen trimer(GO:0005581)
0.1 3.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 3.2 GO:0005814 centriole(GO:0005814)
0.0 2.7 GO:0005884 actin filament(GO:0005884)
0.7 2.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 2.0 GO:0005922 connexon complex(GO:0005922)
0.1 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 GO:0030674 protein binding, bridging(GO:0030674)
0.5 3.0 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 2.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 2.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 2.0 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 2.0 GO:0005243 gap junction channel activity(GO:0005243)
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 1.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.2 1.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.7 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)