Motif ID: Tbx21

Z-value: 1.554


Transcription factors associated with Tbx21:

Gene SymbolEntrez IDGene Name
Tbx21 ENSMUSG00000001444.2 Tbx21



Activity profile for motif Tbx21.

activity profile for motif Tbx21


Sorted Z-values histogram for motif Tbx21

Sorted Z-values for motif Tbx21



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx21

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_170009659 11.478 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr1_-_56969827 11.136 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 11.106 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr9_-_112185726 9.337 ENSMUST00000160240.1
ENSMUST00000162065.1
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_98180866 8.953 ENSMUST00000112959.1
Prdm8
PR domain containing 8
chr11_+_24080664 8.379 ENSMUST00000118955.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr18_+_37020097 7.563 ENSMUST00000047614.1
Pcdha2
protocadherin alpha 2
chr14_+_64588112 7.495 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr7_+_45785331 7.000 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr9_-_112185939 6.959 ENSMUST00000070218.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr3_-_89322883 6.658 ENSMUST00000029673.5
Efna3
ephrin A3
chr5_-_39644634 6.340 ENSMUST00000053116.6
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr5_-_39644597 6.094 ENSMUST00000152057.1
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr15_-_84105662 5.521 ENSMUST00000082365.5
Sult4a1
sulfotransferase family 4A, member 1
chr7_-_126704816 5.036 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr9_-_106656081 4.897 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr8_+_12984246 4.496 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr1_+_62703667 4.480 ENSMUST00000114155.1
ENSMUST00000027112.6
ENSMUST00000063594.6
ENSMUST00000114157.2
Nrp2



neuropilin 2



chr13_-_100108337 4.468 ENSMUST00000180822.1
BC001981
cDNA sequence BC001981
chr5_-_138619751 4.339 ENSMUST00000085852.4
ENSMUST00000110905.2
Zfp68

zinc finger protein 68

chr2_-_66440753 4.328 ENSMUST00000112371.2
ENSMUST00000138910.1
Scn1a

sodium channel, voltage-gated, type I, alpha

chr1_+_62703285 4.222 ENSMUST00000102822.2
ENSMUST00000075144.5
Nrp2

neuropilin 2

chr19_+_44989073 3.998 ENSMUST00000026225.8
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_-_86546795 3.850 ENSMUST00000167814.1
Gm17530
predicted gene, 17530
chr10_-_75560330 3.825 ENSMUST00000051129.9
Fam211b
family with sequence similarity 211, member B
chr6_-_60829826 3.685 ENSMUST00000163779.1
Snca
synuclein, alpha
chr12_-_87233556 3.293 ENSMUST00000021423.7
Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr5_-_138619702 3.254 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr7_-_4789541 3.241 ENSMUST00000168578.1
Tmem238
transmembrane protein 238
chr5_-_138619653 3.175 ENSMUST00000129832.1
Zfp68
zinc finger protein 68
chr18_+_37742088 3.121 ENSMUST00000003599.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr17_-_56074542 3.005 ENSMUST00000139371.1
Ubxn6
UBX domain protein 6
chr11_-_118248590 2.945 ENSMUST00000106305.2
Cyth1
cytohesin 1
chr10_+_7792891 2.893 ENSMUST00000015901.4
Ppil4
peptidylprolyl isomerase (cyclophilin)-like 4
chr8_-_105701077 2.852 ENSMUST00000042608.6
Acd
adrenocortical dysplasia
chr1_+_59912972 2.702 ENSMUST00000036540.5
Fam117b
family with sequence similarity 117, member B
chr3_-_127499095 2.637 ENSMUST00000182594.1
Ank2
ankyrin 2, brain
chr18_+_67088287 2.619 ENSMUST00000025402.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr1_-_133131782 2.566 ENSMUST00000180528.1
Gm26616
predicted gene, 26616
chr6_-_142964404 2.553 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr17_-_33713372 2.510 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr2_+_28641227 2.483 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
Tsc1


tuberous sclerosis 1


chr6_-_101377897 2.478 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr1_+_179546303 2.442 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr6_-_38124568 2.337 ENSMUST00000040259.4
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr2_-_167043494 2.317 ENSMUST00000067584.6
Znfx1
zinc finger, NFX1-type containing 1
chr7_+_128062657 2.228 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
Itgam


integrin alpha M


chr8_-_84822823 2.185 ENSMUST00000065539.4
Dand5
DAN domain family, member 5
chr7_-_29954049 2.183 ENSMUST00000108211.1
ENSMUST00000108205.1
Zfp74

zinc finger protein 74

chr8_+_25849618 2.151 ENSMUST00000098858.3
Kcnu1
potassium channel, subfamily U, member 1
chrX_+_74297097 2.132 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
Atp6ap1



ATPase, H+ transporting, lysosomal accessory protein 1



chrX_-_136868537 2.088 ENSMUST00000058814.6
Rab9b
RAB9B, member RAS oncogene family
chr5_-_36582381 1.924 ENSMUST00000141043.1
ENSMUST00000031094.8
Tbc1d14

TBC1 domain family, member 14

chr4_+_115563649 1.856 ENSMUST00000141033.1
ENSMUST00000030486.8
ENSMUST00000126645.1
ENSMUST00000030480.3
Cyp4a31



cytochrome P450, family 4, subfamily a, polypeptide 31



chr4_-_155669171 1.846 ENSMUST00000103176.3
Mib2
mindbomb homolog 2 (Drosophila)
chr17_+_27029259 1.826 ENSMUST00000053683.6
Ggnbp1
gametogenetin binding protein 1
chr14_+_54426902 1.798 ENSMUST00000010550.7
Mrpl52
mitochondrial ribosomal protein L52
chr4_+_74242468 1.774 ENSMUST00000077851.3
Kdm4c
lysine (K)-specific demethylase 4C
chr9_-_35558522 1.773 ENSMUST00000034612.5
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr11_+_88047302 1.745 ENSMUST00000139129.2
Srsf1
serine/arginine-rich splicing factor 1
chr13_+_104178797 1.702 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr8_+_105701142 1.682 ENSMUST00000098444.2
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr9_-_85749308 1.682 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr7_-_27178835 1.674 ENSMUST00000093040.6
Rab4b
RAB4B, member RAS oncogene family
chr3_-_94436574 1.636 ENSMUST00000029787.4
Oaz3
ornithine decarboxylase antizyme 3
chr1_+_34801704 1.600 ENSMUST00000047664.9
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr2_+_55411790 1.584 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr3_-_89402650 1.533 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep

lens epithelial protein

chr10_-_13868932 1.526 ENSMUST00000019942.5
ENSMUST00000162610.1
Aig1

androgen-induced 1

chr5_-_113989739 1.499 ENSMUST00000077689.7
Ssh1
slingshot homolog 1 (Drosophila)
chr19_-_6128208 1.499 ENSMUST00000025702.7
Snx15
sorting nexin 15
chr2_-_151973840 1.467 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr1_+_153874335 1.438 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr17_-_56074932 1.413 ENSMUST00000019722.5
Ubxn6
UBX domain protein 6
chrX_+_99821021 1.402 ENSMUST00000096363.2
Tmem28
transmembrane protein 28
chr11_+_22971991 1.400 ENSMUST00000049506.5
Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr3_+_106684943 1.365 ENSMUST00000098751.3
Lrif1
ligand dependent nuclear receptor interacting factor 1
chr2_-_151973387 1.325 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr11_+_103171081 1.271 ENSMUST00000042286.5
Fmnl1
formin-like 1
chr16_-_20426322 1.241 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr1_-_179546261 1.201 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr12_-_4874341 1.190 ENSMUST00000137337.1
ENSMUST00000045921.7
Mfsd2b

major facilitator superfamily domain containing 2B

chr5_-_120777628 1.175 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr18_+_9958147 1.163 ENSMUST00000025137.7
Thoc1
THO complex 1
chr14_-_100149764 1.157 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr10_-_13868779 1.157 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr6_+_83101565 1.136 ENSMUST00000101254.3
Ccdc142
coiled-coil domain containing 142
chr12_+_73286868 1.115 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr6_-_113377510 1.113 ENSMUST00000099118.2
Tada3
transcriptional adaptor 3
chr13_-_100650981 1.101 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr4_+_109000770 1.075 ENSMUST00000106644.2
Nrd1
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr12_+_73286779 1.033 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr11_-_120643643 1.027 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr6_-_50261943 0.999 ENSMUST00000167893.1
Dfna5
deafness, autosomal dominant 5 (human)
chr1_+_60409612 0.972 ENSMUST00000052332.8
Abi2
abl-interactor 2
chr13_+_54789500 0.925 ENSMUST00000163915.1
ENSMUST00000099503.3
ENSMUST00000171859.1
Tspan17


tetraspanin 17


chr6_-_50261743 0.877 ENSMUST00000101405.3
ENSMUST00000165099.1
ENSMUST00000170142.1
Dfna5


deafness, autosomal dominant 5 (human)


chr2_-_37703845 0.821 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr19_+_5425121 0.812 ENSMUST00000159759.1
AI837181
expressed sequence AI837181
chr1_-_152090308 0.779 ENSMUST00000044581.7
1700025G04Rik
RIKEN cDNA 1700025G04 gene
chr17_+_6270475 0.773 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr17_+_13760502 0.771 ENSMUST00000139347.1
ENSMUST00000156591.1
ENSMUST00000170827.2
ENSMUST00000139666.1
ENSMUST00000137784.1
ENSMUST00000137708.1
ENSMUST00000150848.1
Mllt4






myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4






chr7_-_13034722 0.739 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr11_-_65162904 0.729 ENSMUST00000093002.5
ENSMUST00000047463.8
Arhgap44

Rho GTPase activating protein 44

chr17_+_30485511 0.728 ENSMUST00000064223.1
Gm9874
predicted gene 9874
chr2_+_30364227 0.677 ENSMUST00000077977.7
ENSMUST00000140075.2
Fam73b

family with sequence similarity 73, member B

chr4_+_154869585 0.670 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
Mmel1


membrane metallo-endopeptidase-like 1


chr11_+_108682602 0.666 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr4_-_117914968 0.652 ENSMUST00000036156.5
Ipo13
importin 13
chr12_-_113260217 0.645 ENSMUST00000178282.1
Igha
immunoglobulin heavy constant alpha
chr9_-_117252450 0.502 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr13_-_8870999 0.498 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
Wdr37


WD repeat domain 37


chr16_-_4003750 0.460 ENSMUST00000171658.1
ENSMUST00000171762.1
Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

chr16_+_75592844 0.453 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
Rbm11


RNA binding motif protein 11


chr10_-_62578387 0.378 ENSMUST00000162525.1
ENSMUST00000159704.1
ENSMUST00000162759.1
ENSMUST00000065887.7
2510003E04Rik



RIKEN cDNA 2510003E04 gene



chr9_+_110419750 0.366 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chr9_+_108049254 0.363 ENSMUST00000112295.2
ENSMUST00000047947.7
Gmppb

GDP-mannose pyrophosphorylase B

chr10_-_39899238 0.333 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chr2_-_176149825 0.332 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr11_-_118415794 0.295 ENSMUST00000164927.1
Cant1
calcium activated nucleotidase 1
chr6_+_113378113 0.253 ENSMUST00000171058.1
ENSMUST00000156898.1
Arpc4

actin related protein 2/3 complex, subunit 4

chr6_-_113377866 0.236 ENSMUST00000032410.7
Tada3
transcriptional adaptor 3
chr6_+_90619241 0.230 ENSMUST00000032177.8
Slc41a3
solute carrier family 41, member 3
chr16_-_20425881 0.184 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr9_+_57148180 0.172 ENSMUST00000105102.2
Gm16493
predicted gene 16493
chrX_-_95444789 0.162 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr1_+_92910758 0.112 ENSMUST00000027487.8
Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr5_-_86676346 0.112 ENSMUST00000038448.6
Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr5_-_120467296 0.105 ENSMUST00000132916.1
Sdsl
serine dehydratase-like
chr17_-_28350600 0.089 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr2_+_84678396 0.082 ENSMUST00000102645.3
Med19
mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr3_+_137918526 0.050 ENSMUST00000168345.1
Lamtor3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr6_-_113377712 0.024 ENSMUST00000113107.1
ENSMUST00000113106.1
Tada3

transcriptional adaptor 3

chr18_-_42579652 0.003 ENSMUST00000054738.3
Gpr151
G protein-coupled receptor 151

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
1.4 22.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.0 2.9 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.9 3.7 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468)
0.8 5.0 GO:0032796 uropod organization(GO:0032796)
0.8 2.5 GO:0043379 memory T cell differentiation(GO:0043379)
0.8 2.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.7 2.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.7 2.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.6 8.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.6 9.0 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.5 4.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.4 18.8 GO:0034605 cellular response to heat(GO:0034605)
0.4 4.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 1.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.4 2.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 1.2 GO:0048296 negative regulation of isotype switching(GO:0045829) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.4 2.2 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3 1.9 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.3 2.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 0.8 GO:0009405 pathogenesis(GO:0009405)
0.3 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.7 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 2.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 4.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.8 GO:0033169 histone H3-K9 demethylation(GO:0033169) regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 1.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 1.5 GO:0071318 cellular response to ATP(GO:0071318)
0.2 0.5 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.2 1.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 4.9 GO:0014047 glutamate secretion(GO:0014047)
0.1 1.3 GO:0051014 actin filament severing(GO:0051014)
0.1 6.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 2.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 2.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 4.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 7.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 2.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.6 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.7 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.9 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 2.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 5.5 GO:0008202 steroid metabolic process(GO:0008202)
0.0 1.7 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 1.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.3 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 2.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 1.8 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.7 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.5 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.4 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.8 2.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.4 2.9 GO:0070187 telosome(GO:0070187)
0.3 2.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 4.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 2.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.8 GO:0033391 chromatoid body(GO:0033391)
0.2 22.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 5.0 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.4 GO:0089701 U2AF(GO:0089701)
0.2 0.7 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.2 0.5 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 1.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.6 GO:0031430 M band(GO:0031430)
0.1 2.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 7.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 3.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 4.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 2.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 4.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.7 GO:0055037 recycling endosome(GO:0055037)
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.9 GO:0005776 autophagosome(GO:0005776)
0.0 8.8 GO:0016604 nuclear body(GO:0016604)
0.0 1.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 7.5 GO:0030424 axon(GO:0030424)
0.0 2.4 GO:0030133 transport vesicle(GO:0030133)
0.0 1.8 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.2 8.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.1 9.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.1 4.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.0 4.9 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.9 2.6 GO:0050827 toxin receptor binding(GO:0050827)
0.7 2.2 GO:0016015 morphogen activity(GO:0016015)
0.7 2.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.6 3.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.5 5.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 2.4 GO:0071253 connexin binding(GO:0071253)
0.4 2.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 1.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.4 1.6 GO:0071532 ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.4 1.9 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.2 4.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 4.3 GO:0031402 sodium ion binding(GO:0031402)
0.2 5.5 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.2 2.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 1.7 GO:0050733 RS domain binding(GO:0050733)
0.2 3.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 6.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 4.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 2.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 16.3 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 3.8 GO:0019003 GDP binding(GO:0019003)
0.1 1.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 2.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 8.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.4 GO:0008905 mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 25.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 2.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.4 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.0 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) DNA-methyltransferase activity(GO:0009008) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 6.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)