Motif ID: Tbx4

Z-value: 1.158


Transcription factors associated with Tbx4:

Gene SymbolEntrez IDGene Name
Tbx4 ENSMUSG00000000094.6 Tbx4



Activity profile for motif Tbx4.

activity profile for motif Tbx4


Sorted Z-values histogram for motif Tbx4

Sorted Z-values for motif Tbx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_134018829 11.520 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr2_+_164562579 7.465 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr9_-_43239816 7.408 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr10_+_26229707 6.896 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr14_-_70642268 6.725 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr6_-_94700137 6.231 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr19_+_20601958 5.064 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr7_-_100658394 4.579 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr10_-_120899067 4.526 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr8_+_45885479 4.326 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr4_+_117849193 4.317 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr11_-_94507337 4.315 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chr1_+_6730051 4.243 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr4_+_117849361 4.191 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr10_-_127341583 4.079 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr12_+_3891728 3.881 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr19_+_55894508 3.420 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr7_-_100658364 3.253 ENSMUST00000107043.1
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_100729917 3.029 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr2_-_148045891 3.027 ENSMUST00000109964.1
Foxa2
forkhead box A2
chrX_+_100730178 3.023 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr1_+_6730135 2.981 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr17_+_29093763 2.893 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr7_-_115824699 2.753 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr1_+_153665666 2.617 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr6_-_24956106 2.600 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr11_+_78178105 2.587 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chrX_-_53269020 2.546 ENSMUST00000114838.1
Fam122b
family with sequence similarity 122, member B
chr5_+_115908644 2.530 ENSMUST00000141101.1
Cit
citron
chr19_-_42202150 2.522 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chrX_+_101383726 2.522 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr1_+_132316112 2.444 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr15_-_38300693 2.410 ENSMUST00000074043.5
Klf10
Kruppel-like factor 10
chr1_+_153665274 2.374 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr9_-_69760924 2.308 ENSMUST00000071281.4
Foxb1
forkhead box B1
chr4_+_11191726 2.217 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2

cyclin E2

chr18_+_5591860 2.206 ENSMUST00000025081.5
ENSMUST00000159390.1
Zeb1

zinc finger E-box binding homeobox 1

chr1_+_153665587 2.192 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 2.189 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr2_+_103970221 2.114 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr2_+_103970115 2.051 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr9_-_95845215 2.030 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr1_-_138847579 1.968 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr7_-_28302238 1.906 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr6_+_15196949 1.894 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr14_+_62292475 1.891 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr4_-_46404224 1.839 ENSMUST00000107764.2
Hemgn
hemogen
chr1_+_66468364 1.761 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr12_+_85473883 1.721 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr12_-_56345862 1.717 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr13_+_113209659 1.687 ENSMUST00000038144.8
Esm1
endothelial cell-specific molecule 1
chr4_-_42168603 1.669 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr4_-_72852622 1.536 ENSMUST00000179234.1
ENSMUST00000078617.4
Aldoart1

aldolase 1 A, retrogene 1

chrX_+_169036610 1.522 ENSMUST00000087016.4
ENSMUST00000112129.1
ENSMUST00000112131.2
Arhgap6


Rho GTPase activating protein 6


chr6_+_7555053 1.504 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr9_+_108296853 1.471 ENSMUST00000035230.5
Amt
aminomethyltransferase
chr13_-_96542479 1.420 ENSMUST00000022172.4
Polk
polymerase (DNA directed), kappa
chr11_-_115813621 1.377 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr7_-_99858872 1.360 ENSMUST00000036274.6
Spcs2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr15_+_10952332 1.295 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr9_+_86743641 1.223 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr5_+_120513102 1.221 ENSMUST00000111889.1
Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr2_-_148046896 1.143 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr9_+_86743616 1.074 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr3_-_75556759 1.019 ENSMUST00000162138.1
ENSMUST00000029424.5
ENSMUST00000161137.1
Pdcd10


programmed cell death 10


chr7_-_141443989 0.969 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr17_-_49564262 0.940 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chrX_+_42151002 0.914 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr4_+_11191354 0.875 ENSMUST00000170901.1
Ccne2
cyclin E2
chr3_+_96629919 0.872 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr2_+_54436317 0.841 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
Galnt13


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13


chr16_-_84835484 0.834 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chrM_+_9452 0.802 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr10_-_128211788 0.773 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr4_+_53440388 0.767 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr10_-_86705485 0.754 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr5_+_31094984 0.713 ENSMUST00000066505.1
Gm9924
predicted gene 9924
chr2_+_138278481 0.700 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chr6_-_28261907 0.667 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr11_-_78751656 0.659 ENSMUST00000059468.4
Fam58b
family with sequence similarity 58, member B
chr14_-_51988829 0.650 ENSMUST00000181008.1
Gm16617
predicted gene, 16617
chr7_-_103813913 0.609 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chr11_+_23306884 0.608 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr10_-_85916902 0.566 ENSMUST00000037646.7
Prdm4
PR domain containing 4
chr15_-_10470490 0.552 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr3_+_51415986 0.535 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr2_-_30178422 0.499 ENSMUST00000100220.4
ENSMUST00000179795.1
D2Wsu81e

DNA segment, Chr 2, Wayne State University 81, expressed

chr13_-_89742490 0.491 ENSMUST00000109546.2
Vcan
versican
chr11_+_78826575 0.457 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9

LYR motif containing 9

chr9_-_102354685 0.427 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1

Eph receptor B1

chr14_+_31251454 0.389 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1
chr1_+_74542881 0.365 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
Plcd4




phospholipase C, delta 4




chr19_+_8617991 0.359 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr6_-_28831747 0.357 ENSMUST00000062304.5
Lrrc4
leucine rich repeat containing 4
chr4_+_53440516 0.348 ENSMUST00000107651.2
ENSMUST00000107647.1
Slc44a1

solute carrier family 44, member 1

chr18_-_46212595 0.317 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr8_+_79028587 0.316 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr3_-_121263159 0.269 ENSMUST00000128909.1
Tmem56
transmembrane protein 56
chr9_-_48495321 0.257 ENSMUST00000170000.2
Rbm7
RNA binding motif protein 7
chr3_-_121263314 0.239 ENSMUST00000029777.7
Tmem56
transmembrane protein 56
chr15_-_81360739 0.226 ENSMUST00000023040.7
Slc25a17
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chr4_-_36056726 0.198 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chrX_+_20425688 0.172 ENSMUST00000115384.2
Phf16
PHD finger protein 16
chr11_+_23306910 0.159 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr16_-_9994921 0.149 ENSMUST00000115835.1
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr10_+_86705811 0.143 ENSMUST00000061458.7
ENSMUST00000075632.6
BC030307

cDNA sequence BC030307

chr13_+_96542727 0.122 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr2_-_13011747 0.086 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr9_+_44326804 0.053 ENSMUST00000054708.3
Dpagt1
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr8_+_105636509 0.046 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr12_-_31634592 0.043 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chr11_-_106301801 0.040 ENSMUST00000103071.3
Gh
growth hormone
chr8_+_79028317 0.020 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr9_+_103008479 0.003 ENSMUST00000035148.6
Slco2a1
solute carrier organic anion transporter family, member 2a1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
2.1 6.2 GO:0032474 otolith morphogenesis(GO:0032474)
1.4 4.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
1.3 11.5 GO:0010587 miRNA catabolic process(GO:0010587)
1.3 5.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.0 4.1 GO:0060032 notochord regression(GO:0060032)
0.9 4.5 GO:0030091 protein repair(GO:0030091)
0.8 2.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.7 9.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.7 2.0 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.6 6.1 GO:0090527 actin filament reorganization(GO:0090527)
0.6 2.3 GO:0007412 axon target recognition(GO:0007412)
0.5 1.5 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.5 1.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 3.9 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.4 3.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.4 1.7 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 2.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 1.9 GO:0007386 compartment pattern specification(GO:0007386)
0.3 2.9 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.3 4.2 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.3 2.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.3 1.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.3 2.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 2.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.2 1.1 GO:0015871 choline transport(GO:0015871)
0.2 1.3 GO:0071638 cellular triglyceride homeostasis(GO:0035356) adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.2 1.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 4.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.2 1.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 2.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 1.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 1.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 3.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 6.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 2.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.8 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 1.4 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.4 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.7 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.8 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.8 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.8 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 3.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 2.3 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.9 GO:0007368 determination of left/right symmetry(GO:0007368)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.5 1.4 GO:0005787 signal peptidase complex(GO:0005787)
0.4 2.0 GO:1990357 terminal web(GO:1990357)
0.4 3.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 1.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 4.1 GO:0097542 ciliary tip(GO:0097542)
0.2 9.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 11.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 2.5 GO:0005922 connexon complex(GO:0005922)
0.2 3.9 GO:0001741 XY body(GO:0001741)
0.2 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 7.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.1 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 6.1 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 2.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 4.3 GO:0030018 Z disc(GO:0030018)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 10.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 6.3 GO:0098793 presynapse(GO:0098793)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.4 8.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.8 5.1 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6 4.5 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.6 11.5 GO:0035198 miRNA binding(GO:0035198)
0.6 6.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.6 1.7 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.5 3.9 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.3 1.2 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.3 1.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 4.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 9.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.5 GO:0005243 gap junction channel activity(GO:0005243)
0.2 2.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 1.5 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.2 0.6 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 7.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 6.4 GO:0070888 E-box binding(GO:0070888)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 4.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0015217 ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.5 GO:0008483 transaminase activity(GO:0008483)
0.1 1.9 GO:0005112 Notch binding(GO:0005112)
0.1 4.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 2.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 7.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.5 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 2.0 GO:0051015 actin filament binding(GO:0051015)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)