Motif ID: Tead1

Z-value: 0.561


Transcription factors associated with Tead1:

Gene SymbolEntrez IDGene Name
Tead1 ENSMUSG00000055320.10 Tead1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112742025_1127420600.144.4e-01Click!


Activity profile for motif Tead1.

activity profile for motif Tead1


Sorted Z-values histogram for motif Tead1

Sorted Z-values for motif Tead1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tead1

PNG image of the network

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Top targets:


Showing 1 to 20 of 103 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_189728264 6.873 ENSMUST00000097442.2
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr15_+_6386598 4.866 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr8_-_47990535 4.218 ENSMUST00000057561.7
Wwc2
WW, C2 and coiled-coil domain containing 2
chr10_+_24595434 2.617 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr10_+_24595623 2.588 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr19_-_4439388 2.522 ENSMUST00000117462.1
ENSMUST00000048197.3
Rhod

ras homolog gene family, member D

chr7_-_109616548 2.376 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr14_-_54577578 2.110 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr18_+_82554463 1.968 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr11_+_70700473 1.898 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
Kif1c



kinesin family member 1C



chr9_-_8004585 1.843 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr15_+_78842632 1.808 ENSMUST00000059619.1
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr2_-_164857542 1.744 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr2_+_156775409 1.732 ENSMUST00000088552.6
Myl9
myosin, light polypeptide 9, regulatory
chr14_-_16575456 1.725 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr18_+_50030977 1.685 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr18_+_61953048 1.662 ENSMUST00000051720.5
Sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr16_+_91225550 1.632 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr11_+_70700606 1.578 ENSMUST00000137119.2
Kif1c
kinesin family member 1C
chr16_-_4559720 1.474 ENSMUST00000005862.7
Tfap4
transcription factor AP4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.9 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
1.1 5.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.3 5.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.0 4.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 3.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.8 2.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 2.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 2.4 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.2 2.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.5 2.2 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.3 2.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.3 2.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 2.0 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.9 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 1.8 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.4 1.7 GO:0042360 vitamin E metabolic process(GO:0042360)
0.3 1.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.7 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 1.7 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 1.7 GO:0070527 platelet aggregation(GO:0070527)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 5.1 GO:0005667 transcription factor complex(GO:0005667)
1.2 4.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 3.6 GO:0016460 myosin II complex(GO:0016460)
0.1 3.5 GO:0005871 kinesin complex(GO:0005871)
0.2 2.0 GO:0033269 internode region of axon(GO:0033269)
0.0 2.0 GO:0055037 recycling endosome(GO:0055037)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.3 0.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 5.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.5 4.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 4.2 GO:0032947 protein complex scaffold(GO:0032947)
0.1 3.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.8 2.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 2.3 GO:0070888 E-box binding(GO:0070888)
0.0 2.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 2.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 2.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.9 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 1.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.4 GO:0030274 LIM domain binding(GO:0030274)