Motif ID: Tfcp2

Z-value: 1.732


Transcription factors associated with Tfcp2:

Gene SymbolEntrez IDGene Name
Tfcp2 ENSMUSG00000009733.8 Tfcp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfcp2mm10_v2_chr15_-_100551959_100552010-0.567.0e-04Click!


Activity profile for motif Tfcp2.

activity profile for motif Tfcp2


Sorted Z-values histogram for motif Tfcp2

Sorted Z-values for motif Tfcp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5390387 11.217 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr8_+_69822429 8.222 ENSMUST00000164890.1
ENSMUST00000034325.4
 Lpar2

lysophosphatidic acid receptor 2

chr16_-_26989974 7.092 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chrX_+_73639414 6.861 ENSMUST00000019701.8
 Dusp9
dual specificity phosphatase 9
chr2_+_163225363 6.433 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr2_-_166155272 6.199 ENSMUST00000088086.3
 Sulf2
sulfatase 2
chr1_-_87156127 6.188 ENSMUST00000160810.1
 Ecel1
endothelin converting enzyme-like 1
chr4_+_115088708 5.932 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
 Pdzk1ip1



PDZK1 interacting protein 1



chr11_+_28853189 5.854 ENSMUST00000020759.5
 Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr5_+_92809372 5.837 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr12_+_24708984 5.499 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr18_+_60925644 5.481 ENSMUST00000115297.1
 Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr2_-_166155624 5.198 ENSMUST00000109249.2
 Sulf2
sulfatase 2
chr18_+_60925612 5.100 ENSMUST00000102888.3
ENSMUST00000025519.4
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr2_-_5012716 4.719 ENSMUST00000027980.7
 Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr8_+_57511833 4.683 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr17_+_34593388 4.604 ENSMUST00000174532.1
 Pbx2
pre B cell leukemia homeobox 2
chr5_-_24577467 4.595 ENSMUST00000030795.8
 Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr1_-_131097535 4.456 ENSMUST00000016672.4
 Mapkapk2
MAP kinase-activated protein kinase 2
chr11_-_22001605 4.386 ENSMUST00000006071.7
 Otx1
orthodenticle homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 124 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 12.5 GO:0006270 DNA replication initiation(GO:0006270)
2.8 11.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.1 11.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.7 10.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 9.0 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.4 8.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.6 7.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
1.5 7.3 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 6.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
1.3 6.3 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 6.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 6.0 GO:0009299 mRNA transcription(GO:0009299)
0.6 5.9 GO:1903975 regulation of glial cell migration(GO:1903975)
0.1 5.8 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.3 5.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.3 5.2 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.7 4.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.5 4.6 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.1 4.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.7 4.5 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.2 GO:0005615 extracellular space(GO:0005615)
2.8 11.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 10.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 9.4 GO:0005912 adherens junction(GO:0005912)
1.1 9.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 7.1 GO:0030139 endocytic vesicle(GO:0030139)
0.1 6.7 GO:0005604 basement membrane(GO:0005604)
1.3 6.3 GO:0070826 paraferritin complex(GO:0070826)
1.0 6.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 5.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.3 5.5 GO:0005652 nuclear lamina(GO:0005652)
0.8 4.7 GO:0031298 replication fork protection complex(GO:0031298)
0.0 4.7 GO:0000793 condensed chromosome(GO:0000793)
0.4 4.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.5 4.2 GO:0070688 MLL5-L complex(GO:0070688)
0.1 4.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 4.0 GO:0000785 chromatin(GO:0000785)
0.8 3.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 3.6 GO:0005813 centrosome(GO:0005813)
0.9 3.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 17.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
2.3 11.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 10.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.8 9.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 8.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 7.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 7.3 GO:0051015 actin filament binding(GO:0051015)
0.1 7.1 GO:0030165 PDZ domain binding(GO:0030165)
0.1 7.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 6.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.3 6.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 6.0 GO:0003746 translation elongation factor activity(GO:0003746)
2.0 5.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 4.9 GO:0003682 chromatin binding(GO:0003682)
0.6 4.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
1.5 4.6 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.8 4.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 4.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 4.3 GO:0003707 steroid hormone receptor activity(GO:0003707)