Motif ID: Tfdp1_Wt1_Egr2
Z-value: 1.762
Transcription factors associated with Tfdp1_Wt1_Egr2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Egr2 | ENSMUSG00000037868.9 | Egr2 |
| Tfdp1 | ENSMUSG00000038482.10 | Tfdp1 |
| Wt1 | ENSMUSG00000016458.7 | Wt1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tfdp1 | mm10_v2_chr8_+_13339656_13339674 | 0.45 | 9.4e-03 | Click! |
| Egr2 | mm10_v2_chr10_+_67537861_67537930 | -0.18 | 3.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 1,243 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 12.3 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.9 | 7.8 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.3 | 6.8 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.4 | 6.4 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.6 | 5.6 | GO:0046499 | S-adenosylmethioninamine metabolic process(GO:0046499) |
| 0.8 | 5.5 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.2 | 5.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 5.3 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.2 | 4.7 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 1.1 | 4.6 | GO:1900145 | regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.1 | 4.5 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.7 | 4.4 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
| 1.1 | 4.3 | GO:0003360 | brainstem development(GO:0003360) |
| 0.9 | 4.3 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 1.0 | 4.2 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
| 0.7 | 4.2 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.3 | 4.2 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.8 | 4.1 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.4 | 4.1 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.4 | 4.0 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 387 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 73.0 | GO:0005634 | nucleus(GO:0005634) |
| 0.2 | 17.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.2 | 13.2 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 12.9 | GO:0005730 | nucleolus(GO:0005730) |
| 0.2 | 12.1 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 11.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 9.3 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 9.1 | GO:0044291 | cell-cell contact zone(GO:0044291) |
| 0.1 | 8.5 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.3 | 7.4 | GO:0001741 | XY body(GO:0001741) |
| 0.2 | 7.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 7.4 | GO:0000776 | kinetochore(GO:0000776) |
| 0.3 | 6.9 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 6.8 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.4 | 6.7 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 6.7 | GO:0005829 | cytosol(GO:0005829) |
| 0.1 | 6.6 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.1 | 5.3 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.2 | 5.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 5.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 679 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 11.9 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 11.3 | GO:0044822 | poly(A) RNA binding(GO:0044822) |
| 0.1 | 10.7 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.3 | 10.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 10.0 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 9.4 | GO:0003682 | chromatin binding(GO:0003682) |
| 1.1 | 9.2 | GO:0046790 | virion binding(GO:0046790) |
| 0.5 | 8.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.4 | 8.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 8.2 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.1 | 6.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.2 | 6.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 6.5 | GO:0042393 | histone binding(GO:0042393) |
| 0.2 | 6.3 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 5.4 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.7 | 5.3 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
| 0.3 | 5.2 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 0.1 | 5.2 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.1 | 5.2 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.1 | 5.2 | GO:0005080 | protein kinase C binding(GO:0005080) |
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