Motif ID: Thra

Z-value: 0.676


Transcription factors associated with Thra:

Gene SymbolEntrez IDGene Name
Thra ENSMUSG00000058756.7 Thra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thramm10_v2_chr11_+_98741805_98741816-0.841.4e-09Click!


Activity profile for motif Thra.

activity profile for motif Thra


Sorted Z-values histogram for motif Thra

Sorted Z-values for motif Thra



Network of associatons between targets according to the STRING database.



First level regulatory network of Thra

PNG image of the network

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Top targets:


Showing 1 to 20 of 197 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_69965396 3.982 ENSMUST00000018713.6
 Cldn7
claudin 7
chr1_+_84839833 3.481 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr13_+_94875600 3.437 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chrX_-_143827391 3.186 ENSMUST00000087316.5
 Capn6
calpain 6
chr5_-_116422858 3.002 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr13_+_44729794 2.932 ENSMUST00000172830.1
 Jarid2
jumonji, AT rich interactive domain 2
chr5_-_134946917 2.762 ENSMUST00000051401.2
 Cldn4
claudin 4
chr4_+_44300876 2.714 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr12_+_79029150 2.219 ENSMUST00000039928.5
 Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr18_+_57142782 2.064 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chrX_-_7967817 2.010 ENSMUST00000033502.7
 Gata1
GATA binding protein 1
chr4_-_137766474 1.958 ENSMUST00000139951.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr17_+_85620816 1.941 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr14_-_118706180 1.910 ENSMUST00000036554.6
ENSMUST00000166646.1
 Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr1_-_163994767 1.701 ENSMUST00000097493.3
ENSMUST00000045876.6
 BC055324

cDNA sequence BC055324

chr12_+_112678803 1.680 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
 Zbtb42


zinc finger and BTB domain containing 42


chr8_-_91801547 1.633 ENSMUST00000093312.4
 Irx3
Iroquois related homeobox 3 (Drosophila)
chr15_-_77842133 1.611 ENSMUST00000016771.6
 Myh9
myosin, heavy polypeptide 9, non-muscle
chrX_-_75843185 1.609 ENSMUST00000137192.1
 Pls3
plastin 3 (T-isoform)
chrX_-_102252154 1.596 ENSMUST00000050551.3
 Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 4.0 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 3.7 GO:0051028 mRNA transport(GO:0051028)
0.1 3.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 3.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 3.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.3 2.8 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 2.8 GO:0060348 bone development(GO:0060348)
0.1 2.7 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 2.6 GO:0043297 apical junction assembly(GO:0043297)
0.6 2.4 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.4 2.1 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.7 2.0 GO:0090202 regulation of primitive erythrocyte differentiation(GO:0010725) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 2.0 GO:0046677 response to antibiotic(GO:0046677)
0.6 1.9 GO:0097402 neuroblast migration(GO:0097402)
0.2 1.9 GO:0006855 drug transmembrane transport(GO:0006855)
0.4 1.6 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.4 1.6 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.2 1.6 GO:0007296 vitellogenesis(GO:0007296)
0.0 1.6 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 4.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 3.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.7 GO:0005902 microvillus(GO:0005902)
0.2 2.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.5 GO:0032420 stereocilium(GO:0032420)
0.0 2.5 GO:0000776 kinetochore(GO:0000776)
0.1 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 2.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.6 1.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 1.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.5 GO:0042587 glycogen granule(GO:0042587)
0.0 1.5 GO:0005840 ribosome(GO:0005840)
0.0 1.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 1.4 GO:0016234 inclusion body(GO:0016234)
0.1 1.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.3 GO:0005198 structural molecule activity(GO:0005198)
0.1 4.2 GO:0032452 histone demethylase activity(GO:0032452)
0.2 3.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 2.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 2.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.5 2.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.0 GO:0051087 chaperone binding(GO:0051087)
0.1 1.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.7 GO:0003774 motor activity(GO:0003774)
0.2 1.6 GO:0043495 protein anchor(GO:0043495)
0.2 1.6 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 1.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.4 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)