Motif ID: Trp53

Z-value: 0.836


Transcription factors associated with Trp53:

Gene SymbolEntrez IDGene Name
Trp53 ENSMUSG00000059552.7 Trp53

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp53mm10_v2_chr11_+_69580359_695803820.261.4e-01Click!


Activity profile for motif Trp53.

activity profile for motif Trp53


Sorted Z-values histogram for motif Trp53

Sorted Z-values for motif Trp53



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp53

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_56377300 3.672 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr15_-_98004695 3.197 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr5_-_116422858 3.136 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr15_-_98004634 2.870 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr17_+_29090969 2.308 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr9_+_66946057 1.937 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr17_-_33890584 1.831 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr14_+_73237891 1.799 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr3_-_132950043 1.777 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
Npnt




nephronectin




chr2_-_69206146 1.745 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr2_-_155074447 1.717 ENSMUST00000137242.1
ENSMUST00000054607.9
Ahcy

S-adenosylhomocysteine hydrolase

chr15_-_102350692 1.651 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr17_-_33890539 1.622 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr1_-_79858627 1.603 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr4_-_135573623 1.563 ENSMUST00000105855.1
Grhl3
grainyhead-like 3 (Drosophila)
chr13_+_113317084 1.543 ENSMUST00000136755.2
BC067074
cDNA sequence BC067074
chr9_-_100486788 1.532 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr14_+_47001336 1.519 ENSMUST00000125113.1
Samd4
sterile alpha motif domain containing 4
chr2_-_164857542 1.498 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr2_-_69206133 1.486 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr9_+_45138437 1.485 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr17_+_87282880 1.397 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr9_-_106158109 1.396 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr4_+_115057683 1.362 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr11_-_17211504 1.358 ENSMUST00000020317.7
Pno1
partner of NOB1 homolog (S. cerevisiae)
chr11_-_3527916 1.348 ENSMUST00000020718.4
Smtn
smoothelin
chr5_-_30073554 1.344 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr15_+_85859689 1.340 ENSMUST00000170629.1
Gtse1
G two S phase expressed protein 1
chr14_-_34374617 1.304 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr8_-_22185758 1.250 ENSMUST00000046916.7
Ckap2
cytoskeleton associated protein 2
chr14_+_74735641 1.232 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr8_+_68880491 1.125 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr4_-_9643638 1.105 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
Asph




aspartate-beta-hydroxylase




chr7_-_98309471 1.098 ENSMUST00000033020.7
Acer3
alkaline ceramidase 3
chr12_-_70231414 1.057 ENSMUST00000161083.1
Pygl
liver glycogen phosphorylase
chr4_+_132351768 1.045 ENSMUST00000172202.1
Gm17300
predicted gene, 17300
chr5_-_138272733 1.019 ENSMUST00000161665.1
ENSMUST00000100530.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr4_-_43030440 0.988 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr6_-_136941494 0.942 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr2_+_59612034 0.929 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr4_+_115057410 0.867 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr11_+_17211912 0.858 ENSMUST00000046955.6
Wdr92
WD repeat domain 92
chr17_+_35821675 0.835 ENSMUST00000003635.6
Ier3
immediate early response 3
chr5_-_138272786 0.825 ENSMUST00000161279.1
ENSMUST00000161647.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr16_-_59632520 0.797 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr11_-_102925086 0.795 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr10_-_81350389 0.781 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr10_-_81350191 0.780 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr14_-_54926784 0.765 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr16_+_20651652 0.751 ENSMUST00000007212.8
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr7_-_64872993 0.728 ENSMUST00000094331.2
Ndnl2
necdin-like 2
chr6_-_136941694 0.727 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr9_-_72985344 0.726 ENSMUST00000124565.2
Gm5918
predicted gene 5918
chr10_-_81350305 0.724 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr14_-_55944536 0.709 ENSMUST00000022834.6
Cma1
chymase 1, mast cell
chr18_+_61639542 0.695 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr5_-_38480131 0.690 ENSMUST00000143758.1
ENSMUST00000067886.5
Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

chr7_+_24884809 0.688 ENSMUST00000156372.1
ENSMUST00000124035.1
Rps19

ribosomal protein S19

chr6_-_136941887 0.684 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr16_+_20717665 0.677 ENSMUST00000021405.7
Polr2h
polymerase (RNA) II (DNA directed) polypeptide H
chr7_-_141010759 0.677 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr4_+_116596672 0.666 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr1_+_88103229 0.664 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr10_+_93641041 0.661 ENSMUST00000020204.4
Ntn4
netrin 4
chr9_-_114982739 0.654 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr2_+_152962485 0.652 ENSMUST00000099197.2
ENSMUST00000103155.3
Ttll9

tubulin tyrosine ligase-like family, member 9

chr10_+_94550852 0.648 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chr15_+_83100281 0.648 ENSMUST00000167389.1
ENSMUST00000166427.1
Serhl

serine hydrolase-like

chr7_+_75455534 0.635 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr18_+_66458587 0.623 ENSMUST00000025399.7
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr17_+_26917091 0.618 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr7_-_114927726 0.609 ENSMUST00000059737.2
Gm6816
predicted gene 6816
chr8_+_94977101 0.573 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr6_+_128438757 0.571 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr15_+_83100201 0.554 ENSMUST00000078218.4
Serhl
serine hydrolase-like
chr11_-_93968293 0.553 ENSMUST00000170303.1
Gm20390
predicted gene 20390
chr9_-_108263706 0.553 ENSMUST00000171412.1
Dag1
dystroglycan 1
chr6_+_134981998 0.553 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr7_+_64392645 0.551 ENSMUST00000037205.8
Mcee
methylmalonyl CoA epimerase
chr3_+_29082539 0.547 ENSMUST00000119598.1
ENSMUST00000118531.1
Egfem1

EGF-like and EMI domain containing 1

chr2_-_155592567 0.543 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
Gss


glutathione synthetase


chr8_-_111854278 0.539 ENSMUST00000034432.5
Cfdp1
craniofacial development protein 1
chr2_-_17731035 0.534 ENSMUST00000028080.5
Nebl
nebulette
chr7_+_24884651 0.526 ENSMUST00000153451.2
ENSMUST00000108429.1
Rps19

ribosomal protein S19

chrX_-_38635066 0.525 ENSMUST00000058265.7
C1galt1c1
C1GALT1-specific chaperone 1
chr1_+_82339049 0.522 ENSMUST00000140020.1
Rhbdd1
rhomboid domain containing 1
chrX_+_74254782 0.505 ENSMUST00000119197.1
ENSMUST00000088313.4
Emd

emerin

chr7_+_24884611 0.505 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr12_+_76255209 0.503 ENSMUST00000021443.5
Mthfd1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
chr17_-_24696147 0.487 ENSMUST00000046839.8
Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr3_+_90669063 0.486 ENSMUST00000069927.8
S100a8
S100 calcium binding protein A8 (calgranulin A)
chr2_+_29890063 0.486 ENSMUST00000028128.6
Odf2
outer dense fiber of sperm tails 2
chr8_-_84893887 0.486 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
Gcdh



glutaryl-Coenzyme A dehydrogenase



chr13_+_21754067 0.462 ENSMUST00000091709.2
Hist1h2bn
histone cluster 1, H2bn
chr9_+_72438534 0.462 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr15_-_77927728 0.458 ENSMUST00000174468.1
ENSMUST00000174529.1
ENSMUST00000173631.1
Txn2


thioredoxin 2


chr1_+_51289106 0.457 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr5_-_38502107 0.454 ENSMUST00000005238.6
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_-_191907527 0.443 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr9_+_38719024 0.440 ENSMUST00000129598.1
Vwa5a
von Willebrand factor A domain containing 5A
chr7_-_28962265 0.432 ENSMUST00000068045.7
Actn4
actinin alpha 4
chr2_-_130664565 0.429 ENSMUST00000089559.4
Ddrgk1
DDRGK domain containing 1
chr2_+_29889217 0.425 ENSMUST00000123335.1
Odf2
outer dense fiber of sperm tails 2
chr10_+_80622677 0.420 ENSMUST00000079773.6
Csnk1g2
casein kinase 1, gamma 2
chr10_+_110745433 0.411 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr11_+_52360824 0.399 ENSMUST00000102758.1
Vdac1
voltage-dependent anion channel 1
chr11_+_88204396 0.397 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
Mrps23



mitochondrial ribosomal protein S23



chr12_+_59129720 0.396 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chr1_-_184883218 0.389 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr5_+_114707760 0.382 ENSMUST00000094441.4
Tchp
trichoplein, keratin filament binding
chr14_+_13454010 0.373 ENSMUST00000112656.2
Synpr
synaptoporin
chr11_-_93968242 0.359 ENSMUST00000107844.2
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr7_-_28962223 0.358 ENSMUST00000127210.1
Actn4
actinin alpha 4
chr9_+_72438519 0.356 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr12_+_59129757 0.336 ENSMUST00000069430.8
ENSMUST00000177370.1
Ctage5

CTAGE family, member 5

chr9_-_26999491 0.330 ENSMUST00000060513.7
ENSMUST00000120367.1
Acad8

acyl-Coenzyme A dehydrogenase family, member 8

chr9_-_21963568 0.315 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr3_-_90389884 0.312 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr5_+_34989473 0.305 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr14_-_70653081 0.301 ENSMUST00000062629.4
Npm2
nucleophosmin/nucleoplasmin 2
chr3_-_28765364 0.293 ENSMUST00000094335.3
Gm6505
predicted pseudogene 6505
chr2_+_10372426 0.284 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2


Scm-like with four mbt domains 2


chr9_-_70141484 0.277 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr9_+_65346066 0.267 ENSMUST00000048184.2
Pdcd7
programmed cell death 7
chrX_-_37191160 0.242 ENSMUST00000016571.7
Ndufa1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr1_+_161969179 0.238 ENSMUST00000111594.2
ENSMUST00000028021.6
Pigc

phosphatidylinositol glycan anchor biosynthesis, class C

chr16_+_91391721 0.237 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr2_+_129100995 0.237 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B

chr7_+_30712209 0.236 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr2_+_112454997 0.225 ENSMUST00000069747.5
Emc7
ER membrane protein complex subunit 7
chr13_+_22035821 0.222 ENSMUST00000110455.2
Hist1h2bk
histone cluster 1, H2bk
chr1_+_6487231 0.221 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr3_+_96172327 0.216 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr8_+_9977707 0.166 ENSMUST00000139793.1
ENSMUST00000048216.5
Abhd13

abhydrolase domain containing 13

chr14_-_59365410 0.161 ENSMUST00000161031.1
ENSMUST00000160425.1
Phf11d

PHD finger protein 11D

chr4_-_83285141 0.160 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr4_-_96591555 0.143 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr4_-_42084291 0.141 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr14_+_13453937 0.138 ENSMUST00000153954.1
Synpr
synaptoporin
chr4_-_129641060 0.134 ENSMUST00000046425.9
ENSMUST00000133803.1
Txlna

taxilin alpha

chr9_+_61373219 0.110 ENSMUST00000162583.1
ENSMUST00000161993.1
ENSMUST00000160882.1
ENSMUST00000160724.1
ENSMUST00000162973.1
ENSMUST00000159050.1
Tle3





transducin-like enhancer of split 3, homolog of Drosophila E(spl)





chr1_+_161969284 0.106 ENSMUST00000160881.1
ENSMUST00000159648.1
Pigc

phosphatidylinositol glycan anchor biosynthesis, class C

chr12_-_55492587 0.094 ENSMUST00000021413.7
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr17_-_34862473 0.087 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb


complement factor B


chr17_-_45595842 0.082 ENSMUST00000164618.1
ENSMUST00000097317.3
ENSMUST00000170113.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr9_+_107576915 0.080 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr18_-_20002093 0.074 ENSMUST00000115848.3
Dsc3
desmocollin 3
chr12_-_81532840 0.070 ENSMUST00000166664.1
ENSMUST00000164386.1
ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
Gm20498

Synj2bp


predicted gene 20498

synaptojanin 2 binding protein


chr19_+_44203265 0.064 ENSMUST00000026220.5
Scd3
stearoyl-coenzyme A desaturase 3
chr19_-_43524462 0.060 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chrX_+_6415736 0.057 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr2_+_180078623 0.054 ENSMUST00000087563.6
Mtg2
mitochondrial ribosome associated GTPase 2
chr9_-_59486323 0.049 ENSMUST00000165322.1
Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr19_-_47138280 0.046 ENSMUST00000140512.1
ENSMUST00000035822.1
Calhm2

calcium homeostasis modulator 2

chr12_+_82170016 0.045 ENSMUST00000166429.1
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr19_+_4097392 0.043 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr11_+_55469677 0.030 ENSMUST00000018727.3
G3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr4_-_129640959 0.029 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna


taxilin alpha


chr7_-_103741322 0.027 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chr4_-_149099802 0.024 ENSMUST00000103217.4
Pex14
peroxisomal biogenesis factor 14
chr6_-_134897815 0.021 ENSMUST00000165392.1
ENSMUST00000046255.7
ENSMUST00000111932.1
ENSMUST00000116515.2
Gpr19



G protein-coupled receptor 19



chr14_-_103843685 0.015 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chrX_-_142306170 0.012 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr17_+_32506446 0.006 ENSMUST00000165999.1
Cyp4f17
cytochrome P450, family 4, subfamily f, polypeptide 17
chr6_+_39592569 0.006 ENSMUST00000135671.1
ENSMUST00000119379.1
Ndufb2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2

chr11_-_102469839 0.004 ENSMUST00000103086.3
Itga2b
integrin alpha 2b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.9 3.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.7 2.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.5 1.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.5 6.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.5 1.5 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.5 2.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.4 1.3 GO:0046078 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078)
0.4 1.7 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.4 1.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.4 1.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 1.0 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.3 1.2 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 1.8 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.3 2.3 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 1.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 0.8 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 0.7 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.2 1.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.8 GO:0046909 intermembrane transport(GO:0046909)
0.2 0.5 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 1.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 0.5 GO:0070488 neutrophil aggregation(GO:0070488)
0.2 2.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.8 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.6 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.1 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.5 GO:0006547 histidine metabolic process(GO:0006547)
0.1 1.5 GO:0099625 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.6 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.6 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 1.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.1 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.0 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.1 0.5 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.9 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.5 GO:0046686 response to cadmium ion(GO:0046686)
0.0 1.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 3.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 2.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.6 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.0 0.9 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0036376 regulation of proton transport(GO:0010155) sodium ion export from cell(GO:0036376)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.7 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 1.7 GO:0009566 fertilization(GO:0009566)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.4 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.7 2.2 GO:0033193 Lsd1/2 complex(GO:0033193)
0.6 2.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.5 3.2 GO:0031262 Ndc80 complex(GO:0031262)
0.5 6.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 3.7 GO:0005916 fascia adherens(GO:0005916)
0.2 1.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 3.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 1.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.8 GO:0000235 astral microtubule(GO:0000235)
0.1 1.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.6 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 3.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.1 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.7 3.7 GO:0071253 connexin binding(GO:0071253)
0.4 1.2 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.4 6.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 1.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 1.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 1.1 GO:0032052 bile acid binding(GO:0032052)
0.3 2.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 1.0 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.3 1.9 GO:0008494 translation activator activity(GO:0008494)
0.2 1.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.1 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.5 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 2.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 2.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0050786 arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786)
0.1 1.3 GO:0005542 folic acid binding(GO:0005542)
0.1 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 1.5 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.3 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.8 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0016594 glycine binding(GO:0016594)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0052890 acyl-CoA dehydrogenase activity(GO:0003995) oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.2 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.6 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 2.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 1.1 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)