Motif ID: Trp53
Z-value: 0.836
Transcription factors associated with Trp53:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Trp53 | ENSMUSG00000059552.7 | Trp53 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Trp53 | mm10_v2_chr11_+_69580359_69580382 | 0.26 | 1.4e-01 | Click! |
Top targets:
Showing 1 to 20 of 166 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 73 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 6.1 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 1.2 | 3.7 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
| 0.9 | 3.5 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.0 | 3.2 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.5 | 2.4 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.3 | 2.3 | GO:0071493 | cellular response to UV-B(GO:0071493) |
| 0.2 | 2.3 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.7 | 2.2 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
| 0.0 | 2.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 1.9 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.3 | 1.8 | GO:0010694 | positive regulation of alkaline phosphatase activity(GO:0010694) |
| 0.4 | 1.7 | GO:0060266 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268) |
| 0.2 | 1.7 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 1.7 | GO:0009566 | fertilization(GO:0009566) |
| 0.5 | 1.6 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.2 | 1.6 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.5 | 1.5 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
| 0.4 | 1.5 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.1 | 1.5 | GO:0099625 | regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625) |
| 0.0 | 1.4 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 33 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 6.1 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.3 | 3.7 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 3.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 3.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.5 | 3.2 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.0 | 2.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.8 | 2.3 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.6 | 2.3 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
| 0.7 | 2.2 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
| 0.4 | 1.8 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.2 | 1.6 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.1 | 1.5 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.0 | 1.2 | GO:0005604 | basement membrane(GO:0005604) |
| 0.2 | 1.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.2 | 1.1 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 1.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 1.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.1 | 0.9 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 0.8 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.1 | 0.8 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 56 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.7 | 3.7 | GO:0071253 | connexin binding(GO:0071253) |
| 0.9 | 3.5 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.3 | 2.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.0 | 2.4 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.2 | 2.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 2.3 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.0 | 2.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.3 | 1.9 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 1.8 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.0 | 1.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.2 | 1.7 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 1.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 1.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.4 | 1.5 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.2 | 1.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 1.5 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.1 | 1.3 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 1.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.4 | 1.2 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
