Motif ID: Trp73

Z-value: 0.601


Transcription factors associated with Trp73:

Gene SymbolEntrez IDGene Name
Trp73 ENSMUSG00000029026.10 Trp73

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp73mm10_v2_chr4_-_154097105_1540971730.373.2e-02Click!


Activity profile for motif Trp73.

activity profile for motif Trp73


Sorted Z-values histogram for motif Trp73

Sorted Z-values for motif Trp73



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp73

PNG image of the network

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Top targets:


Showing 1 to 20 of 80 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_48261427 2.815 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr15_+_99055164 1.797 ENSMUST00000047104.7
ENSMUST00000024249.3
 Prph

peripherin

chr1_+_72824482 1.554 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr12_-_45074112 1.506 ENSMUST00000120531.1
ENSMUST00000143376.1
 Stxbp6

syntaxin binding protein 6 (amisyn)

chr2_-_164857542 1.477 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein



chr2_-_164857671 1.406 ENSMUST00000059954.7
 Pltp
phospholipid transfer protein
chr7_-_116308241 1.365 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
 Plekha7


pleckstrin homology domain containing, family A member 7


chr3_+_159839729 1.256 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr16_-_17125106 1.203 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr17_+_29090969 1.107 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr9_-_58158498 1.106 ENSMUST00000168864.2
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr12_-_45074457 1.102 ENSMUST00000053768.6
 Stxbp6
syntaxin binding protein 6 (amisyn)
chr1_+_153665274 1.002 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr4_+_101068983 0.998 ENSMUST00000038463.8
ENSMUST00000106955.1
 Raver2

ribonucleoprotein, PTB-binding 2

chrX_+_10717390 0.977 ENSMUST00000115524.1
ENSMUST00000008179.6
 Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr7_-_116038734 0.970 ENSMUST00000166877.1
 Sox6
SRY-box containing gene 6
chr14_+_53665912 0.967 ENSMUST00000181768.1
 Trav3-3
T cell receptor alpha variable 3-3
chr18_+_56432116 0.950 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr4_-_11386757 0.927 ENSMUST00000108313.1
ENSMUST00000108311.2
 Esrp1

epithelial splicing regulatory protein 1

chr7_-_141443314 0.915 ENSMUST00000106005.2
 Lrdd
leucine-rich and death domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.9 GO:0042360 vitamin E metabolic process(GO:0042360)
0.7 2.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.3 2.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 1.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 1.6 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.2 1.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.3 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 1.1 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.1 1.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 1.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.0 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.3 0.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 0.5 GO:0033566 gamma-tubulin complex localization(GO:0033566)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 GO:0000145 exocyst(GO:0000145)
0.6 1.8 GO:0044299 C-fiber(GO:0044299)
0.1 1.4 GO:0005915 zonula adherens(GO:0005915)
0.0 1.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 1.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.6 GO:0000811 GINS complex(GO:0000811)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0045120 telomerase holoenzyme complex(GO:0005697) pronucleus(GO:0045120)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 0.8 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.6 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.5 GO:0005118 sevenless binding(GO:0005118)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.3 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)