Motif ID: Wrnip1_Mta3_Rcor1

Z-value: 2.837

Transcription factors associated with Wrnip1_Mta3_Rcor1:

Gene SymbolEntrez IDGene Name
Mta3 ENSMUSG00000055817.11 Mta3
Rcor1 ENSMUSG00000037896.11 Rcor1
Wrnip1 ENSMUSG00000021400.6 Wrnip1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rcor1mm10_v2_chr12_+_111039334_111039400-0.251.6e-01Click!
Mta3mm10_v2_chr17_+_83706170_83706200-0.057.7e-01Click!
Wrnip1mm10_v2_chr13_+_32802007_32802152-0.048.4e-01Click!


Activity profile for motif Wrnip1_Mta3_Rcor1.

activity profile for motif Wrnip1_Mta3_Rcor1


Sorted Z-values histogram for motif Wrnip1_Mta3_Rcor1

Sorted Z-values for motif Wrnip1_Mta3_Rcor1



Network of associatons between targets according to the STRING database.



First level regulatory network of Wrnip1_Mta3_Rcor1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_120202104 7.474 ENSMUST00000033198.5
 Crym
crystallin, mu
chr5_+_127241807 7.160 ENSMUST00000119026.1
 Tmem132c
transmembrane protein 132C
chr16_+_92498122 6.513 ENSMUST00000023670.3
 Clic6
chloride intracellular channel 6
chr14_+_33923582 6.114 ENSMUST00000168727.1
 Gdf10
growth differentiation factor 10
chr2_+_145167706 5.477 ENSMUST00000110007.1
 Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr7_-_142657466 5.413 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr1_-_171196229 5.028 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr4_-_66404512 4.745 ENSMUST00000068214.4
 Astn2
astrotactin 2
chr18_+_20665250 4.691 ENSMUST00000075312.3
 Ttr
transthyretin
chr14_+_122475397 4.631 ENSMUST00000075888.5
 Zic2
zinc finger protein of the cerebellum 2
chr2_-_80447625 4.612 ENSMUST00000028389.3
 Frzb
frizzled-related protein
chrX_+_73483602 4.483 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr11_-_68386821 4.415 ENSMUST00000021284.3
 Ntn1
netrin 1
chr5_-_37824580 4.306 ENSMUST00000063116.9
 Msx1
msh homeobox 1
chr18_+_58836721 4.209 ENSMUST00000052907.5
 Adamts19
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
chr7_-_66427469 4.193 ENSMUST00000015278.7
 Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr7_-_45103747 4.098 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr11_-_75422586 4.088 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr6_-_115994953 4.083 ENSMUST00000015511.8
 Plxnd1
plexin D1
chr11_+_101246405 4.067 ENSMUST00000122006.1
ENSMUST00000151830.1
 Ramp2

receptor (calcitonin) activity modifying protein 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,586 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 16.5 GO:0006910 phagocytosis, recognition(GO:0006910)
2.6 13.0 GO:0070327 thyroid hormone transport(GO:0070327)
2.2 13.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
1.6 12.6 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.4 12.0 GO:0070206 protein trimerization(GO:0070206)
0.2 11.9 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
1.3 11.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.1 11.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 11.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.4 11.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.5 11.3 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.5 10.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
2.2 10.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 10.7 GO:0032355 response to estradiol(GO:0032355)
0.8 10.6 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.5 10.5 GO:0046596 regulation of viral entry into host cell(GO:0046596)
1.6 9.7 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 9.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.9 9.3 GO:1903598 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) positive regulation of gap junction assembly(GO:1903598)
1.4 8.4 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 407 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 513.7 GO:0016021 integral component of membrane(GO:0016021)
0.1 144.1 GO:0005576 extracellular region(GO:0005576)
0.2 106.8 GO:0005615 extracellular space(GO:0005615)
0.6 102.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 77.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 68.7 GO:0005924 cell-substrate adherens junction(GO:0005924)
0.7 49.4 GO:0005604 basement membrane(GO:0005604)
0.8 46.6 GO:0005581 collagen trimer(GO:0005581)
0.2 38.3 GO:0000139 Golgi membrane(GO:0000139)
0.2 20.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 19.3 GO:0031012 extracellular matrix(GO:0031012)
0.2 17.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 17.4 GO:0031225 anchored component of membrane(GO:0031225)
0.2 17.1 GO:0015935 small ribosomal subunit(GO:0015935)
0.1 16.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 13.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.7 12.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 11.4 GO:0005667 transcription factor complex(GO:0005667)
0.2 11.2 GO:0005811 lipid particle(GO:0005811)
1.4 10.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 809 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 41.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 29.6 GO:0005178 integrin binding(GO:0005178)
0.7 29.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.8 23.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 23.1 GO:0008201 heparin binding(GO:0008201)
0.6 21.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.4 21.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.8 21.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.8 18.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.6 18.5 GO:0004364 glutathione transferase activity(GO:0004364)
1.0 17.4 GO:0015026 coreceptor activity(GO:0015026)
0.5 16.8 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
2.1 16.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 16.3 GO:0005080 protein kinase C binding(GO:0005080)
0.4 14.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.6 13.0 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.2 10.8 GO:0017171 serine hydrolase activity(GO:0017171)
0.8 10.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 9.8 GO:0005496 steroid binding(GO:0005496)
1.2 9.7 GO:0008199 ferric iron binding(GO:0008199)