Motif ID: Xbp1_Creb3l1

Z-value: 0.964

Transcription factors associated with Xbp1_Creb3l1:

Gene SymbolEntrez IDGene Name
Creb3l1 ENSMUSG00000027230.9 Creb3l1
Xbp1 ENSMUSG00000020484.12 Xbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l1mm10_v2_chr2_-_92024502_920245290.576.0e-04Click!
Xbp1mm10_v2_chr11_+_5520652_5520659-0.086.5e-01Click!


Activity profile for motif Xbp1_Creb3l1.

activity profile for motif Xbp1_Creb3l1


Sorted Z-values histogram for motif Xbp1_Creb3l1

Sorted Z-values for motif Xbp1_Creb3l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Xbp1_Creb3l1

PNG image of the network

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Top targets:


Showing 1 to 20 of 167 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_45092130 5.785 ENSMUST00000148175.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_45092198 4.636 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
 Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr15_+_79516396 4.408 ENSMUST00000010974.7
 Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr7_-_45091713 2.869 ENSMUST00000141576.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr2_-_105399286 2.537 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr3_+_93520473 2.525 ENSMUST00000029515.4
 S100a11
S100 calcium binding protein A11 (calgizzarin)
chr7_+_128523576 2.280 ENSMUST00000033136.7
 Bag3
BCL2-associated athanogene 3
chr6_-_54593139 2.118 ENSMUST00000046520.6
 Fkbp14
FK506 binding protein 14
chr3_-_27710413 2.049 ENSMUST00000046157.4
 Fndc3b
fibronectin type III domain containing 3B
chr6_+_29348069 2.010 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
 Calu


calumenin


chr5_-_135251209 1.973 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chr6_-_101377342 1.864 ENSMUST00000151175.1
 Pdzrn3
PDZ domain containing RING finger 3
chr13_-_38528412 1.826 ENSMUST00000035988.8
 Txndc5
thioredoxin domain containing 5
chr10_+_91082940 1.792 ENSMUST00000020150.3
 Ikbip
IKBKB interacting protein
chr1_-_163313661 1.784 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
 Prrx1


paired related homeobox 1


chr7_-_142578093 1.640 ENSMUST00000149974.1
ENSMUST00000152754.1
 H19

H19 fetal liver mRNA

chr11_+_3514861 1.633 ENSMUST00000094469.4
 Selm
selenoprotein M
chr7_-_142578139 1.608 ENSMUST00000136359.1
 H19
H19 fetal liver mRNA
chr3_+_96697100 1.575 ENSMUST00000107077.3
 Pias3
protein inhibitor of activated STAT 3
chr10_+_91083036 1.567 ENSMUST00000020149.5
 Ikbip
IKBKB interacting protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 5.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 3.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3 3.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 3.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 2.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 2.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 2.0 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 2.0 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 1.8 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.4 1.6 GO:0035934 corticosterone secretion(GO:0035934)
0.1 1.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 1.5 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.2 1.5 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.2 1.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.5 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 32.6 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 5.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.4 GO:0005844 polysome(GO:0005844)
0.0 2.6 GO:0005811 lipid particle(GO:0005811)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.1 2.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.9 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 1.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 0.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.7 GO:0005509 calcium ion binding(GO:0005509)
1.3 5.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 3.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 2.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.7 GO:0020037 heme binding(GO:0020037)
0.4 1.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.4 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 1.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 1.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 1.1 GO:0004096 catalase activity(GO:0004096)
0.3 1.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 1.0 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)