Motif ID: Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Z-value: 5.419

Transcription factors associated with Ybx1_Nfya_Nfyb_Nfyc_Cebpz:

Gene SymbolEntrez IDGene Name
Cebpz ENSMUSG00000024081.8 Cebpz
Nfya ENSMUSG00000023994.7 Nfya
Nfyb ENSMUSG00000020248.12 Nfyb
Nfyc ENSMUSG00000032897.11 Nfyc
Ybx1 ENSMUSG00000028639.8 Ybx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ybx1mm10_v2_chr4_-_119294520_1192946040.802.1e-08Click!
Nfycmm10_v2_chr4_-_120815703_1208157610.637.6e-05Click!
Cebpzmm10_v2_chr17_-_78937031_78937074-0.593.4e-04Click!
Nfybmm10_v2_chr10_-_82764088_82764144-0.466.9e-03Click!
Nfyamm10_v2_chr17_-_48409729_48409906-0.038.8e-01Click!


Activity profile for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz.

activity profile for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz


Sorted Z-values histogram for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Sorted Z-values for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz



Network of associatons between targets according to the STRING database.



First level regulatory network of Ybx1_Nfya_Nfyb_Nfyc_Cebpz

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_83955507 27.495 ENSMUST00000005607.8
 Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr16_-_17125106 23.768 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr3_-_89418287 19.207 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr6_+_124829582 19.013 ENSMUST00000024270.7
 Cdca3
cell division cycle associated 3
chr7_-_120982260 16.069 ENSMUST00000033169.8
 Cdr2
cerebellar degeneration-related 2
chr17_-_24251382 15.783 ENSMUST00000115390.3
 Ccnf
cyclin F
chr11_-_97187872 15.700 ENSMUST00000001479.4
 Kpnb1
karyopherin (importin) beta 1
chr6_+_124830217 14.587 ENSMUST00000131847.1
ENSMUST00000151674.1
 Cdca3

cell division cycle associated 3

chr14_+_46760526 14.537 ENSMUST00000067426.4
 Cdkn3
cyclin-dependent kinase inhibitor 3
chr14_+_19751257 14.348 ENSMUST00000022340.3
 Nid2
nidogen 2
chr6_+_124829540 14.102 ENSMUST00000150120.1
 Cdca3
cell division cycle associated 3
chr2_+_34772089 12.958 ENSMUST00000028222.6
ENSMUST00000100171.2
 Hspa5

heat shock protein 5

chr6_-_82774448 12.786 ENSMUST00000000642.4
 Hk2
hexokinase 2
chrX_+_58030622 12.743 ENSMUST00000088627.4
 Zic3
zinc finger protein of the cerebellum 3
chr8_+_57511833 11.822 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr13_-_53473074 11.805 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chr11_-_87108656 11.583 ENSMUST00000051395.8
 Prr11
proline rich 11
chr14_-_52104015 11.350 ENSMUST00000111610.4
ENSMUST00000164655.1
 Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr11_+_87109221 11.291 ENSMUST00000020794.5
 Ska2
spindle and kinetochore associated complex subunit 2
chr13_-_56252163 10.999 ENSMUST00000058475.4
 Neurog1
neurogenin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 665 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 65.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
4.0 47.4 GO:0007100 mitotic centrosome separation(GO:0007100)
0.2 46.0 GO:0007067 mitotic nuclear division(GO:0007067)
1.3 40.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
2.7 30.1 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
1.2 26.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
1.3 26.3 GO:0006270 DNA replication initiation(GO:0006270)
1.9 24.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.3 21.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
1.0 21.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
3.6 21.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
3.0 21.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.3 21.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.7 20.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
1.7 20.4 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
1.3 20.0 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
1.0 19.9 GO:0006298 mismatch repair(GO:0006298)
0.6 19.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.5 19.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
6.5 19.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 272 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 68.4 GO:0005925 focal adhesion(GO:0005925)
0.1 63.6 GO:0005615 extracellular space(GO:0005615)
0.2 61.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 58.3 GO:0005634 nucleus(GO:0005634)
3.9 50.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 48.7 GO:0000776 kinetochore(GO:0000776)
2.8 38.9 GO:0031616 spindle pole centrosome(GO:0031616)
6.9 34.5 GO:0097149 centralspindlin complex(GO:0097149)
2.3 33.9 GO:0042555 MCM complex(GO:0042555)
0.7 32.0 GO:0005657 replication fork(GO:0005657)
0.4 29.9 GO:0005814 centriole(GO:0005814)
0.5 29.3 GO:0005643 nuclear pore(GO:0005643)
1.1 28.1 GO:0005680 anaphase-promoting complex(GO:0005680)
1.4 27.8 GO:0045120 pronucleus(GO:0045120)
5.5 27.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 25.1 GO:0030496 midbody(GO:0030496)
1.5 19.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 18.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
2.3 18.7 GO:0005818 aster(GO:0005818)
0.5 18.4 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 406 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 66.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.4 50.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.6 45.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.6 40.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.8 34.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.8 33.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 32.6 GO:0051087 chaperone binding(GO:0051087)
0.2 32.5 GO:0008017 microtubule binding(GO:0008017)
0.2 32.3 GO:0042393 histone binding(GO:0042393)
0.1 29.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.4 27.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 26.4 GO:0001047 core promoter binding(GO:0001047)
0.4 25.6 GO:0003777 microtubule motor activity(GO:0003777)
0.4 23.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 23.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
1.8 23.2 GO:0008301 DNA binding, bending(GO:0008301)
2.9 22.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.4 21.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.5 20.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
6.8 20.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)