Motif ID: Yy1_Yy2

Z-value: 4.053

Transcription factors associated with Yy1_Yy2:

Gene SymbolEntrez IDGene Name
Yy1 ENSMUSG00000021264.11 Yy1
Yy2 ENSMUSG00000091736.2 Yy2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Yy2mm10_v2_chrX_-_157598642_157598655-0.441.1e-02Click!
Yy1mm10_v2_chr12_+_108792946_108792988-0.096.3e-01Click!


Activity profile for motif Yy1_Yy2.

activity profile for motif Yy1_Yy2


Sorted Z-values histogram for motif Yy1_Yy2

Sorted Z-values for motif Yy1_Yy2



Network of associatons between targets according to the STRING database.



First level regulatory network of Yy1_Yy2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22163299 16.759 ENSMUST00000100052.4
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr19_+_25610533 16.601 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr11_+_94741782 11.948 ENSMUST00000021240.6
 Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr3_+_146121655 10.868 ENSMUST00000039450.4
 Mcoln3
mucolipin 3
chr7_-_103843154 10.531 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr3_-_90213577 9.428 ENSMUST00000170122.2
 Rps27
ribosomal protein S27
chr7_-_137314394 9.427 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr12_+_109459843 9.127 ENSMUST00000173812.1
 Dlk1
delta-like 1 homolog (Drosophila)
chr14_-_76237353 9.037 ENSMUST00000095471.4
 Rps2-ps6
ribosomal protein S2, pseudogene 6
chr11_+_32276893 9.023 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr17_-_23829095 8.814 ENSMUST00000069579.5
 Tceb2
transcription elongation factor B (SIII), polypeptide 2
chr10_-_77113676 8.680 ENSMUST00000072755.4
ENSMUST00000105409.1
 Col18a1

collagen, type XVIII, alpha 1

chr10_-_128549102 8.572 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chr9_+_50603892 8.360 ENSMUST00000044051.4
 Timm8b
translocase of inner mitochondrial membrane 8B
chr7_+_29289300 8.342 ENSMUST00000048187.4
 Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr7_-_78783026 8.340 ENSMUST00000032841.5
 Mrpl46
mitochondrial ribosomal protein L46
chr8_-_107263248 8.155 ENSMUST00000080443.6
 Rps18-ps3
ribosomal protein S18, pseudogene 3
chr9_+_107399858 8.136 ENSMUST00000085092.5
ENSMUST00000164988.2
 Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr10_-_128549125 8.106 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
 Rpl41


ribosomal protein L41


chr15_-_78544345 7.917 ENSMUST00000053239.2
 Sstr3
somatostatin receptor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 877 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 70.9 GO:0042254 ribosome biogenesis(GO:0042254)
0.2 56.6 GO:0006412 translation(GO:0006412)
1.1 45.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.5 45.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.5 40.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.8 37.3 GO:0032543 mitochondrial translation(GO:0032543)
1.7 36.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 29.0 GO:0051028 mRNA transport(GO:0051028)
5.4 26.8 GO:0015671 oxygen transport(GO:0015671)
1.5 26.1 GO:0043248 proteasome assembly(GO:0043248)
0.4 25.5 GO:0006413 translational initiation(GO:0006413)
0.6 23.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.6 22.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.6 18.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.2 17.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
5.7 17.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.6 17.1 GO:0006284 base-excision repair(GO:0006284)
0.6 17.0 GO:0006270 DNA replication initiation(GO:0006270)
1.1 15.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
1.1 15.4 GO:0010388 cullin deneddylation(GO:0010388)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 358 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 136.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.9 88.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 78.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 47.4 GO:0005730 nucleolus(GO:0005730)
1.0 46.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.1 44.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.2 39.6 GO:0015935 small ribosomal subunit(GO:0015935)
1.0 32.4 GO:0000788 nuclear nucleosome(GO:0000788)
1.5 30.9 GO:0005839 proteasome core complex(GO:0005839)
0.6 30.4 GO:0005840 ribosome(GO:0005840)
0.6 27.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.6 26.1 GO:0000786 nucleosome(GO:0000786)
3.0 24.3 GO:0005833 hemoglobin complex(GO:0005833)
0.3 22.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 21.9 GO:0005739 mitochondrion(GO:0005739)
0.5 21.5 GO:0008180 COP9 signalosome(GO:0008180)
0.3 17.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
1.1 17.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.9 17.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
2.8 16.8 GO:0061689 tricellular tight junction(GO:0061689)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 553 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 300.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 102.5 GO:0044822 poly(A) RNA binding(GO:0044822)
0.8 45.2 GO:0003743 translation initiation factor activity(GO:0003743)
2.0 32.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 31.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
1.4 29.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 28.2 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.4 27.8 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA methyltransferase activity(GO:0008649) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) rRNA (uridine) methyltransferase activity(GO:0016436) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
5.4 26.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.8 22.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 21.7 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
1.2 21.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.4 21.5 GO:0003684 damaged DNA binding(GO:0003684)
0.4 19.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.4 18.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 17.3 GO:0003724 RNA helicase activity(GO:0003724)
0.9 16.3 GO:0055103 ligase regulator activity(GO:0055103)
0.4 16.1 GO:0008536 Ran GTPase binding(GO:0008536)
2.0 16.0 GO:0008097 5S rRNA binding(GO:0008097)
0.6 16.0 GO:0008432 JUN kinase binding(GO:0008432)