Motif ID: Zbtb12

Z-value: 0.638


Transcription factors associated with Zbtb12:

Gene SymbolEntrez IDGene Name
Zbtb12 ENSMUSG00000049823.8 Zbtb12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb12mm10_v2_chr17_+_34894515_34894573-0.326.7e-02Click!


Activity profile for motif Zbtb12.

activity profile for motif Zbtb12


Sorted Z-values histogram for motif Zbtb12

Sorted Z-values for motif Zbtb12



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb12

PNG image of the network

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Top targets:


Showing 1 to 20 of 59 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_37367354 4.310 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr17_-_27029009 2.206 ENSMUST00000078691.5
Bak1
BCL2-antagonist/killer 1
chr14_-_103844173 2.093 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr11_+_54902743 2.074 ENSMUST00000082430.3
Gpx3
glutathione peroxidase 3
chr11_+_54902917 2.030 ENSMUST00000149324.1
Gpx3
glutathione peroxidase 3
chr4_-_151057933 1.945 ENSMUST00000030797.3
Vamp3
vesicle-associated membrane protein 3
chr3_-_84155762 1.916 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr5_+_92603039 1.668 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr11_-_12027958 1.658 ENSMUST00000109654.1
Grb10
growth factor receptor bound protein 10
chr6_+_90462562 1.633 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr6_-_124814288 1.571 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr19_-_10240689 1.550 ENSMUST00000088013.5
Myrf
myelin regulatory factor
chr3_+_88081997 1.520 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr9_+_22411515 1.368 ENSMUST00000058868.7
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr11_-_88718078 1.319 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr1_+_69826986 1.210 ENSMUST00000065425.5
ENSMUST00000113940.2
Spag16

sperm associated antigen 16

chr7_+_92875253 1.195 ENSMUST00000076052.6
Prcp
prolylcarboxypeptidase (angiotensinase C)
chr8_-_45382198 1.150 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr2_-_28916668 1.121 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr15_-_88954400 1.102 ENSMUST00000109371.1
Ttll8
tubulin tyrosine ligase-like family, member 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.3 GO:0007050 cell cycle arrest(GO:0007050)
0.2 4.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.7 2.2 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.7 2.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 1.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 1.9 GO:0051321 meiotic cell cycle(GO:0051321)
0.2 1.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 1.7 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.5 1.6 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 1.6 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 1.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 1.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 1.2 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.4 1.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.1 GO:0030901 midbrain development(GO:0030901)
0.3 0.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.3 0.8 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 0.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0046930 pore complex(GO:0046930)
0.1 1.9 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.3 GO:0005844 polysome(GO:0005844)
0.1 1.2 GO:0044447 axoneme part(GO:0044447)
0.0 1.2 GO:0045178 basal part of cell(GO:0045178)
0.2 1.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.1 GO:0008430 selenium binding(GO:0008430)
0.2 2.2 GO:0051400 BH domain binding(GO:0051400)
0.7 2.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 1.7 GO:2001069 glycogen binding(GO:2001069)
0.1 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 1.5 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.3 0.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)