Motif ID: Zbtb3

Z-value: 0.507


Transcription factors associated with Zbtb3:

Gene SymbolEntrez IDGene Name
Zbtb3 ENSMUSG00000071661.6 Zbtb3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb3mm10_v2_chr19_+_8802486_88025300.467.0e-03Click!


Activity profile for motif Zbtb3.

activity profile for motif Zbtb3


Sorted Z-values histogram for motif Zbtb3

Sorted Z-values for motif Zbtb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 116 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_96132568 1.166 ENSMUST00000161263.1
 Sv2c
synaptic vesicle glycoprotein 2c
chr1_-_162859684 1.138 ENSMUST00000131058.1
 Fmo1
flavin containing monooxygenase 1
chr8_+_10272572 0.993 ENSMUST00000042103.8
 Myo16
myosin XVI
chr9_-_89622986 0.932 ENSMUST00000044491.6
 AF529169
cDNA sequence AF529169
chr19_-_58455903 0.884 ENSMUST00000131877.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr5_+_115908644 0.827 ENSMUST00000141101.1
 Cit
citron
chr8_+_85492568 0.819 ENSMUST00000034136.5
 Gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr15_-_67113909 0.775 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr1_-_172258410 0.731 ENSMUST00000111243.1
 Atp1a4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr1_-_133921393 0.696 ENSMUST00000048432.5
 Prelp
proline arginine-rich end leucine-rich repeat
chr19_-_4334001 0.580 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A
chr3_-_104961695 0.527 ENSMUST00000029429.4
 Wnt2b
wingless related MMTV integration site 2b
chr19_+_25236959 0.522 ENSMUST00000049400.8
 Kank1
KN motif and ankyrin repeat domains 1
chr3_+_79885930 0.515 ENSMUST00000029567.8
 Fam198b
family with sequence similarity 198, member B
chr17_+_24549950 0.471 ENSMUST00000035565.3
 Pkd1
polycystic kidney disease 1 homolog
chr7_-_118995211 0.468 ENSMUST00000008878.8
 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chrX_+_166238923 0.459 ENSMUST00000060210.7
ENSMUST00000112233.1
 Gpm6b

glycoprotein m6b

chr10_+_76253848 0.440 ENSMUST00000036387.7
 S100b
S100 protein, beta polypeptide, neural
chr3_-_57847478 0.432 ENSMUST00000120289.1
ENSMUST00000066882.8
 Pfn2

profilin 2

chr9_+_44069421 0.429 ENSMUST00000114830.2
 Usp2
ubiquitin specific peptidase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.8 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.7 GO:0036376 sodium ion export from cell(GO:0036376)
0.2 0.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.6 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.2 0.5 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.5 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 0.5 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 0.4 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.4 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.1 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.5 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138) external encapsulating structure(GO:0030312)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 0.6 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) cobalt ion binding(GO:0050897)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)