Motif ID: Zbtb4

Z-value: 0.834


Transcription factors associated with Zbtb4:

Gene SymbolEntrez IDGene Name
Zbtb4 ENSMUSG00000018750.8 Zbtb4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb4mm10_v2_chr11_+_69765899_697659250.763.5e-07Click!


Activity profile for motif Zbtb4.

activity profile for motif Zbtb4


Sorted Z-values histogram for motif Zbtb4

Sorted Z-values for motif Zbtb4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 5.838 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr6_+_141524379 5.570 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr7_-_19699008 4.993 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
 Apoe





apolipoprotein E





chr1_+_34678176 4.948 ENSMUST00000159747.2
 Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr16_+_11984581 4.930 ENSMUST00000170672.2
ENSMUST00000023138.7
 Shisa9

shisa homolog 9 (Xenopus laevis)

chr11_-_3504766 3.475 ENSMUST00000044507.5
 Inpp5j
inositol polyphosphate 5-phosphatase J
chr2_-_170427828 3.358 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
 Bcas1


breast carcinoma amplified sequence 1


chr2_+_124610278 3.284 ENSMUST00000051419.8
ENSMUST00000077847.5
ENSMUST00000078621.5
ENSMUST00000076335.5
 Sema6d



sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D



chr8_-_105637403 3.060 ENSMUST00000182046.1
 Gm5914
predicted gene 5914
chr15_+_74563738 2.921 ENSMUST00000170845.1
 Bai1
brain-specific angiogenesis inhibitor 1
chr2_+_124610573 2.827 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr9_-_70657121 2.635 ENSMUST00000049031.5
 Fam63b
family with sequence similarity 63, member B
chr11_+_100574904 2.589 ENSMUST00000103120.4
 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr18_-_39490649 2.575 ENSMUST00000115567.1
 Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr2_-_73386396 2.237 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
 Gpr155


G protein-coupled receptor 155


chrX_+_41401304 2.235 ENSMUST00000076349.5
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr8_+_70501116 2.068 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr8_-_64693027 1.995 ENSMUST00000048967.7
 Cpe
carboxypeptidase E
chr10_+_39732099 1.914 ENSMUST00000019986.6
 Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr10_+_100015817 1.843 ENSMUST00000130190.1
ENSMUST00000020129.7
 Kitl

kit ligand


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.4 5.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.8 5.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.3 5.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.7 5.0 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.1 3.9 GO:0046847 filopodium assembly(GO:0046847)
0.2 3.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 3.5 GO:0001919 regulation of receptor recycling(GO:0001919)
0.9 2.6 GO:0030070 insulin processing(GO:0030070)
0.5 2.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 2.6 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.5 2.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 2.3 GO:0008209 androgen metabolic process(GO:0008209)
0.4 2.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.3 2.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.3 2.0 GO:0005513 detection of calcium ion(GO:0005513)
0.5 1.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.5 1.9 GO:0097494 regulation of vesicle size(GO:0097494)
0.1 1.7 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.4 1.6 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.7 5.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.5 4.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 4.0 GO:0043083 synaptic cleft(GO:0043083)
0.5 3.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 3.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.7 2.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.5 1.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.1 GO:0030215 semaphorin receptor binding(GO:0030215)
1.4 5.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 5.6 GO:0030165 PDZ domain binding(GO:0030165)
1.7 5.0 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 4.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.6 4.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.2 3.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.6 2.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 2.6 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.2 GO:0032183 SUMO binding(GO:0032183)
0.3 2.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 2.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) cobalt ion binding(GO:0050897)
0.1 2.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.3 1.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.6 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)