Motif ID: Zbtb6

Z-value: 0.717


Transcription factors associated with Zbtb6:

Gene SymbolEntrez IDGene Name
Zbtb6 ENSMUSG00000066798.3 Zbtb6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6mm10_v2_chr2_-_37443096_374431780.458.1e-03Click!


Activity profile for motif Zbtb6.

activity profile for motif Zbtb6


Sorted Z-values histogram for motif Zbtb6

Sorted Z-values for motif Zbtb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb6

PNG image of the network

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Top targets:


Showing 1 to 20 of 198 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102897123 4.586 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr11_-_102897146 3.373 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr6_+_114131229 3.231 ENSMUST00000032451.7
 Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr1_-_133131782 2.706 ENSMUST00000180528.1
 Gm26616
predicted gene, 26616
chr14_+_27238018 2.541 ENSMUST00000049206.5
 Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr4_-_120287349 1.995 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr5_+_36796228 1.774 ENSMUST00000181278.1
 Gm26605
predicted gene, 26605
chr11_+_3488275 1.677 ENSMUST00000064265.6
 Pla2g3
phospholipase A2, group III
chr6_+_124997062 1.647 ENSMUST00000159391.1
 Pianp
PILR alpha associated neural protein
chr11_-_114066174 1.620 ENSMUST00000041627.7
 Sdk2
sidekick homolog 2 (chicken)
chr12_-_83951355 1.488 ENSMUST00000181399.1
 Gm26571
predicted gene, 26571
chr16_-_45158566 1.461 ENSMUST00000181177.1
 Slc35a5
solute carrier family 35, member A5
chr16_-_45158624 1.454 ENSMUST00000180636.1
 Slc35a5
solute carrier family 35, member A5
chr1_-_162859684 1.430 ENSMUST00000131058.1
 Fmo1
flavin containing monooxygenase 1
chr16_-_45158453 1.425 ENSMUST00000181750.1
 Slc35a5
solute carrier family 35, member A5
chr6_+_124996681 1.409 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein
chr17_-_17624458 1.398 ENSMUST00000041047.2
 Lnpep
leucyl/cystinyl aminopeptidase
chr5_-_18360384 1.364 ENSMUST00000074694.5
 Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr5_-_120588613 1.344 ENSMUST00000046426.8
 Tpcn1
two pore channel 1
chr16_-_45158650 1.321 ENSMUST00000023344.3
 Slc35a5
solute carrier family 35, member A5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 8.0 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.2 4.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 3.8 GO:0008643 carbohydrate transport(GO:0008643)
0.2 2.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 2.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.7 2.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 2.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 2.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.5 1.8 GO:0009414 response to water deprivation(GO:0009414)
0.4 1.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 1.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.2 1.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.4 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.4 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.4 GO:0043171 peptide catabolic process(GO:0043171)
0.2 1.2 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.4 1.1 GO:0061743 motor learning(GO:0061743)
0.4 1.1 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.0 1.0 GO:1902476 chloride transmembrane transport(GO:1902476)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 8.0 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 6.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.3 GO:0043235 receptor complex(GO:0043235)
0.0 2.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 1.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.1 GO:0044301 climbing fiber(GO:0044301)
0.0 1.0 GO:0043025 neuronal cell body(GO:0043025)
0.1 0.8 GO:0042581 specific granule(GO:0042581)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 0.7 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.2 0.6 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 5.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
1.1 3.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.3 1.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.4 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 1.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 1.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 1.1 GO:0038025 reelin receptor activity(GO:0038025)
0.1 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.1 GO:0032947 protein complex scaffold(GO:0032947)
0.2 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)