Motif ID: Zbtb7c

Z-value: 0.954


Transcription factors associated with Zbtb7c:

Gene SymbolEntrez IDGene Name
Zbtb7c ENSMUSG00000044646.8 Zbtb7c

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7cmm10_v2_chr18_+_75820174_758202100.192.9e-01Click!


Activity profile for motif Zbtb7c.

activity profile for motif Zbtb7c


Sorted Z-values histogram for motif Zbtb7c

Sorted Z-values for motif Zbtb7c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7c

PNG image of the network

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Top targets:


Showing 1 to 20 of 121 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_127263346 8.268 ENSMUST00000099172.3
 Kif5a
kinesin family member 5A
chr11_+_104231573 7.236 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr2_-_29253001 6.604 ENSMUST00000071201.4
 Ntng2
netrin G2
chr11_+_104231515 6.405 ENSMUST00000106993.3
 Mapt
microtubule-associated protein tau
chr11_+_104231465 6.187 ENSMUST00000145227.1
 Mapt
microtubule-associated protein tau
chr18_+_32938955 5.137 ENSMUST00000042868.4
 Camk4
calcium/calmodulin-dependent protein kinase IV
chr10_+_93589413 5.040 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr4_-_120287349 4.858 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr3_+_107036156 4.079 ENSMUST00000052718.3
 Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr11_-_26210553 3.825 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr4_-_22488296 3.495 ENSMUST00000178174.1
 Pou3f2
POU domain, class 3, transcription factor 2
chr11_+_75531690 3.461 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
 Slc43a2



solute carrier family 43, member 2



chr16_+_11984581 3.224 ENSMUST00000170672.2
ENSMUST00000023138.7
 Shisa9

shisa homolog 9 (Xenopus laevis)

chr10_-_79874211 3.105 ENSMUST00000167897.1
 BC005764
cDNA sequence BC005764
chr1_+_55406163 2.866 ENSMUST00000042986.8
 Plcl1
phospholipase C-like 1
chr15_-_100599983 2.846 ENSMUST00000073837.6
 Pou6f1
POU domain, class 6, transcription factor 1
chr11_+_93996082 2.759 ENSMUST00000041956.7
 Spag9
sperm associated antigen 9
chr15_-_100599864 2.698 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1

chr14_-_55560340 2.648 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr10_+_111164794 2.548 ENSMUST00000105275.1
ENSMUST00000095310.1
 Osbpl8

oxysterol binding protein-like 8


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 19.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 8.5 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 8.3 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 7.4 GO:0015807 L-amino acid transport(GO:0015807)
0.0 5.6 GO:0007409 axonogenesis(GO:0007409)
0.3 5.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 4.9 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 4.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.3 3.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 3.3 GO:0035418 protein localization to synapse(GO:0035418)
0.2 3.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 2.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 2.8 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.6 2.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.5 2.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 2.4 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.5 2.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.4 2.2 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 2.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.8 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 19.8 GO:0045298 tubulin complex(GO:0045298)
0.0 10.9 GO:0005730 nucleolus(GO:0005730)
0.6 8.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 7.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 7.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 6.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 3.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 2.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 2.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 1.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.5 GO:0043196 varicosity(GO:0043196)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.3 1.2 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.3 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 19.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.6 8.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 7.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 5.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 4.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 4.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 4.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 3.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.2 2.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 2.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 2.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.8 2.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 2.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 2.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)