Motif ID: Zfhx3

Z-value: 1.043


Transcription factors associated with Zfhx3:

Gene SymbolEntrez IDGene Name
Zfhx3 ENSMUSG00000038872.8 Zfhx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfhx3mm10_v2_chr8_+_108714644_108714644-0.067.4e-01Click!


Activity profile for motif Zfhx3.

activity profile for motif Zfhx3


Sorted Z-values histogram for motif Zfhx3

Sorted Z-values for motif Zfhx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfhx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_143933204 10.432 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr13_-_110280103 9.405 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chrX_-_143933089 8.352 ENSMUST00000087313.3
Dcx
doublecortin
chr10_-_110000219 6.118 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr14_+_64588112 5.582 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr3_+_28263205 5.169 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr1_-_126830632 4.954 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr17_+_35076902 4.762 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr4_+_13743424 4.678 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_86485407 4.159 ENSMUST00000034987.8
Dopey1
dopey family member 1
chr11_+_24078173 4.132 ENSMUST00000109514.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr4_+_101507947 3.919 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr16_-_74411776 3.791 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr6_-_101377897 3.685 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr18_+_37518341 3.638 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr3_+_136670076 3.329 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr13_+_83732438 3.278 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr5_+_107497718 3.230 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr2_-_63184253 3.201 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr11_+_24078022 3.154 ENSMUST00000000881.6
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr2_+_82053222 3.072 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr8_+_47713266 3.041 ENSMUST00000180928.1
E030037K01Rik
RIKEN cDNA E030037K01 gene
chr1_-_12991109 3.021 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr1_+_179961110 2.651 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr12_+_71170589 2.606 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr11_+_24078111 2.577 ENSMUST00000109516.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr4_-_32923455 2.532 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr1_-_158814469 2.499 ENSMUST00000161589.2
Pappa2
pappalysin 2
chrX_+_163911401 2.463 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chrM_-_14060 2.351 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr8_+_93810832 2.272 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr9_+_113812547 2.240 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr1_-_132390301 2.223 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr5_+_107497762 2.191 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr2_-_37647199 2.139 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chrM_+_9870 2.122 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr8_+_83666827 1.934 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr1_-_24612700 1.871 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr9_+_95857597 1.794 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chr3_+_76075583 1.690 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chrM_+_14138 1.634 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr5_-_107875035 1.535 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr1_+_179960472 1.398 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr2_-_63184170 1.386 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr8_-_9976294 1.361 ENSMUST00000095476.4
Lig4
ligase IV, DNA, ATP-dependent
chr6_+_127453667 1.357 ENSMUST00000112193.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr10_+_115384951 1.320 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr1_-_126830786 1.303 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr2_+_3770673 1.057 ENSMUST00000177037.1
Fam107b
family with sequence similarity 107, member B
chr6_-_38124568 1.046 ENSMUST00000040259.4
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr1_+_172698046 1.043 ENSMUST00000038495.3
Crp
C-reactive protein, pentraxin-related
chr2_-_165368723 1.030 ENSMUST00000141140.1
ENSMUST00000103085.1
Zfp663

zinc finger protein 663

chr10_-_56228636 0.983 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr9_-_22208546 0.971 ENSMUST00000167359.1
1810064F22Rik
RIKEN cDNA 1810064F22 gene
chr10_-_17947997 0.827 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr2_+_120977017 0.805 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr1_+_125676969 0.781 ENSMUST00000027581.6
Gpr39
G protein-coupled receptor 39
chr7_+_55794146 0.757 ENSMUST00000032627.3
Tubgcp5
tubulin, gamma complex associated protein 5
chr1_-_157256682 0.716 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr10_+_23796946 0.659 ENSMUST00000119597.1
ENSMUST00000179321.1
Slc18b1

solute carrier family 18, subfamily B, member 1

chr7_-_34655500 0.628 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr8_-_67818284 0.626 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr2_-_86347764 0.622 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr7_+_19119853 0.620 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr2_-_140671462 0.613 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr2_+_177768044 0.605 ENSMUST00000108942.3
Gm14322
predicted gene 14322
chr5_+_25246775 0.568 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr10_+_23797052 0.530 ENSMUST00000133289.1
Slc18b1
solute carrier family 18, subfamily B, member 1
chr2_-_72986716 0.527 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr9_+_36832684 0.497 ENSMUST00000034630.8
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr19_+_48206025 0.495 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr2_-_140671400 0.452 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chrX_-_111536325 0.446 ENSMUST00000156639.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr12_-_54695885 0.431 ENSMUST00000067272.8
Eapp
E2F-associated phosphoprotein
chr11_+_4986824 0.426 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr9_-_120068263 0.420 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr4_+_82065924 0.408 ENSMUST00000161588.1
Gm5860
predicted gene 5860
chr2_-_121235689 0.386 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr18_+_55057557 0.386 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chrX_+_107255878 0.383 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr3_-_130730375 0.380 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr12_-_12941827 0.379 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_-_120245157 0.292 ENSMUST00000090071.4
Pla2g4e
phospholipase A2, group IVE
chr2_-_140671440 0.204 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr10_+_90576252 0.189 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr1_+_164275559 0.161 ENSMUST00000027867.6
Ccdc181
coiled-coil domain containing 181
chr2_+_110597298 0.102 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr12_-_54695829 0.051 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp



E2F-associated phosphoprotein



chr4_+_109343029 0.016 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.1 3.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.0 18.8 GO:0021860 pyramidal neuron development(GO:0021860)
1.0 5.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.8 9.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.7 3.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.6 1.8 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.4 1.3 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 2.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 1.6 GO:0033762 response to glucagon(GO:0033762)
0.3 0.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 3.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 1.4 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.2 4.0 GO:0007097 nuclear migration(GO:0007097)
0.2 1.0 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.0 GO:0032929 negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929)
0.2 4.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 2.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.8 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.4 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
0.1 0.6 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 8.0 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 4.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 3.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 2.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 2.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 2.5 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 2.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 4.6 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 1.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.5 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 1.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 2.6 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.4 GO:0043029 T cell homeostasis(GO:0043029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.6 3.3 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 1.6 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 0.8 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 3.8 GO:0030673 axolemma(GO:0030673)
0.1 3.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.8 GO:0001741 XY body(GO:0001741)
0.1 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 3.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 9.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 4.0 GO:0042641 actomyosin(GO:0042641)
0.0 5.2 GO:0055037 recycling endosome(GO:0055037)
0.0 17.6 GO:0005874 microtubule(GO:0005874)
0.0 2.6 GO:0005814 centriole(GO:0005814)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 7.1 GO:0016604 nuclear body(GO:0016604)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 4.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0070469 respiratory chain(GO:0070469)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.8 18.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.6 3.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 1.9 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.4 3.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 9.4 GO:0031489 myosin V binding(GO:0031489)
0.4 2.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.8 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.3 3.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 4.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 1.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 2.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 9.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 5.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 3.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 2.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 4.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 3.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)