Motif ID: Zfp105

Z-value: 0.626


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_122923099-0.373.4e-02Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 5.485 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr8_-_109251698 3.910 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr8_+_128359065 3.904 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr5_+_17574268 3.889 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr18_+_69344503 3.390 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr5_+_13399309 3.132 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr15_+_99006056 2.819 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr15_-_81843699 2.275 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr10_-_96409038 2.009 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr12_-_90738438 1.958 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr13_-_67609667 1.946 ENSMUST00000012873.8
 AA987161
expressed sequence AA987161
chr5_+_19907502 1.802 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_36968679 1.683 ENSMUST00000067700.6
 Ccser2
coiled-coil serine rich 2
chr4_+_144892813 1.623 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr18_+_37484955 1.622 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr8_+_93810832 1.589 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr6_-_142964404 1.572 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr13_-_67609617 1.114 ENSMUST00000138725.1
 AA987161
expressed sequence AA987161
chr11_-_101466222 1.063 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)
chr8_+_20567716 0.903 ENSMUST00000178995.1
 Gm21092
predicted gene, 21092
chr4_+_11704439 0.837 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr18_+_30272747 0.766 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
 Pik3c3


phosphoinositide-3-kinase, class 3


chr10_+_128267997 0.699 ENSMUST00000050901.2
 Apof
apolipoprotein F
chr1_+_171419027 0.651 ENSMUST00000171362.1
 Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr5_-_111761697 0.646 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr9_+_78175898 0.624 ENSMUST00000180974.1
 C920006O11Rik
RIKEN cDNA C920006O11 gene
chr12_-_99393010 0.599 ENSMUST00000177451.1
 Foxn3
forkhead box N3
chr8_+_20136455 0.589 ENSMUST00000179299.1
ENSMUST00000096485.4
 Gm21811

predicted gene, 21811

chr1_+_179960472 0.577 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr15_+_78983041 0.519 ENSMUST00000109687.1
ENSMUST00000109688.1
ENSMUST00000130663.2
 Triobp


TRIO and F-actin binding protein


chr2_+_107290590 0.503 ENSMUST00000037012.2
 Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr14_+_31019159 0.483 ENSMUST00000112094.1
ENSMUST00000144009.1
 Pbrm1

polybromo 1

chr13_-_21501418 0.398 ENSMUST00000044043.2
 Gm11273
predicted gene 11273
chr11_-_22286795 0.340 ENSMUST00000109563.2
ENSMUST00000180360.1
 Ehbp1

EH domain binding protein 1

chr1_-_63114516 0.318 ENSMUST00000097718.2
 Ino80d
INO80 complex subunit D
chr5_+_136953246 0.308 ENSMUST00000111094.1
ENSMUST00000111097.1
 Fis1

fission 1 (mitochondrial outer membrane) homolog (yeast)

chr6_-_99632376 0.224 ENSMUST00000176255.1
 Gm20696
predicted gene 20696
chr4_+_105157339 0.187 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr6_-_99435345 0.127 ENSMUST00000113322.2
ENSMUST00000176850.1
ENSMUST00000176632.1
 Foxp1


forkhead box P1


chr8_-_79399513 0.073 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
 Smad1


SMAD family member 1


chr1_-_184732616 0.066 ENSMUST00000048572.6
 Hlx
H2.0-like homeobox
chr2_-_177267036 0.059 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr8_+_57488053 0.029 ENSMUST00000180690.1
 2500002B13Rik
RIKEN cDNA 2500002B13 gene
chr7_-_34313531 0.028 ENSMUST00000108074.1
 4931406P16Rik
RIKEN cDNA 4931406P16 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 10.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4 2.0 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.4 5.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 3.4 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.3 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 1.8 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.2 0.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 1.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.6 GO:0051926 dopamine receptor signaling pathway(GO:0007212) negative regulation of calcium ion transport(GO:0051926)
0.0 0.3 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.8 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.7 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0097443 sorting endosome(GO:0097443)
0.4 1.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 3.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.6 7.0 GO:0038191 neuropilin binding(GO:0038191)
0.3 1.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.5 GO:0030955 potassium ion binding(GO:0030955)
0.0 1.1 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)