Motif ID: Zfp219_Zfp740

Z-value: 1.012

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp740mm10_v2_chr15_+_102203639_1022037090.317.5e-02Click!
Zfp219mm10_v2_chr14_-_52020698_52020737-0.019.8e-01Click!


Activity profile for motif Zfp219_Zfp740.

activity profile for motif Zfp219_Zfp740


Sorted Z-values histogram for motif Zfp219_Zfp740

Sorted Z-values for motif Zfp219_Zfp740



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_48949495 2.775 ENSMUST00000112745.1
 Mbd5
methyl-CpG binding domain protein 5
chr1_-_56972437 2.771 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr12_-_27342696 2.720 ENSMUST00000079063.5
 Sox11
SRY-box containing gene 11
chr10_-_127620922 2.444 ENSMUST00000118455.1
 Lrp1
low density lipoprotein receptor-related protein 1
chr11_-_69369377 2.391 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr13_-_29984219 2.205 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr7_+_127511976 2.177 ENSMUST00000098025.4
 Srcap
Snf2-related CREBBP activator protein
chr16_+_44173271 2.133 ENSMUST00000088356.4
ENSMUST00000169582.1
 Gm608

predicted gene 608

chr7_+_127777095 2.121 ENSMUST00000144406.1
 Setd1a
SET domain containing 1A
chr10_-_127620960 1.867 ENSMUST00000121829.1
 Lrp1
low density lipoprotein receptor-related protein 1
chr12_+_102949450 1.861 ENSMUST00000179002.1
 Unc79
unc-79 homolog (C. elegans)
chr3_+_28263563 1.818 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
 Tnik






TRAF2 and NCK interacting kinase






chr2_-_45113216 1.794 ENSMUST00000124942.1
 Zeb2
zinc finger E-box binding homeobox 2
chr1_-_64121389 1.748 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr9_-_44881274 1.626 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
 Kmt2a


lysine (K)-specific methyltransferase 2A


chr18_-_43393346 1.587 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr6_+_4903350 1.572 ENSMUST00000175962.1
 Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr2_-_116065798 1.484 ENSMUST00000110907.1
ENSMUST00000110908.2
 Meis2

Meis homeobox 2

chr2_-_45113255 1.434 ENSMUST00000068415.4
ENSMUST00000127520.1
 Zeb2

zinc finger E-box binding homeobox 2

chr2_-_120850364 1.407 ENSMUST00000131389.1
 Ttbk2
tau tubulin kinase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 189 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.9 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.4 5.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.9 4.5 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.7 4.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 3.2 GO:1990403 embryonic brain development(GO:1990403)
0.1 3.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.9 2.8 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.9 2.7 GO:0060023 soft palate development(GO:0060023)
0.3 2.6 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.8 2.3 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 2.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.5 2.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.4 2.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 2.2 GO:0000077 DNA damage checkpoint(GO:0000077)
0.2 2.0 GO:0051764 actin crosslink formation(GO:0051764)
0.2 1.9 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.6 1.8 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0 1.8 GO:0006284 base-excision repair(GO:0006284)
0.3 1.7 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 1.7 GO:0061029 eyelid development in camera-type eye(GO:0061029)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 5.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 3.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 3.2 GO:0010369 chromocenter(GO:0010369)
0.1 3.2 GO:0035869 ciliary transition zone(GO:0035869)
0.1 2.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 2.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.4 GO:0031941 filamentous actin(GO:0031941)
0.5 2.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 2.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.1 GO:1990391 DNA repair complex(GO:1990391)
0.4 1.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 1.8 GO:0044327 dendritic spine head(GO:0044327)
0.2 1.7 GO:0032584 growth cone membrane(GO:0032584)
0.4 1.3 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.3 GO:0055037 recycling endosome(GO:0055037)
0.3 1.2 GO:0090537 CERF complex(GO:0090537)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.0 GO:0003682 chromatin binding(GO:0003682)
0.3 4.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 4.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 4.4 GO:0070412 R-SMAD binding(GO:0070412)
0.2 3.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 3.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.9 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.1 2.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 2.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 2.4 GO:1990188 euchromatin binding(GO:1990188)
0.0 2.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.8 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 1.7 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.4 1.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.6 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) DNA-methyltransferase activity(GO:0009008) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1 1.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 1.4 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 1.2 GO:0003708 retinoic acid receptor activity(GO:0003708)