Motif ID: Zfp423

Z-value: 0.499


Transcription factors associated with Zfp423:

Gene SymbolEntrez IDGene Name
Zfp423 ENSMUSG00000045333.9 Zfp423

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp423mm10_v2_chr8_-_87804411_878044630.231.9e-01Click!


Activity profile for motif Zfp423.

activity profile for motif Zfp423


Sorted Z-values histogram for motif Zfp423

Sorted Z-values for motif Zfp423



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp423

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_22344690 2.584 ENSMUST00000062372.7
ENSMUST00000161356.1
Reln

reelin

chr7_-_70360593 1.448 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr10_-_62110945 1.370 ENSMUST00000142821.1
ENSMUST00000124615.1
ENSMUST00000064050.4
ENSMUST00000125704.1
ENSMUST00000142796.1
2010107G23Rik




RIKEN cDNA 2010107G23 gene




chr7_+_29307924 1.340 ENSMUST00000108230.1
ENSMUST00000065181.5
Dpf1

D4, zinc and double PHD fingers family 1

chr19_+_7268296 1.332 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr11_-_94474088 1.225 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr2_+_180499893 1.122 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr2_+_106693185 1.038 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr12_+_102948843 1.035 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr12_+_109459843 0.927 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr5_-_135934590 0.900 ENSMUST00000055808.5
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr17_+_55986494 0.879 ENSMUST00000011733.8
Fsd1
fibronectin type 3 and SPRY domain-containing protein
chr4_+_42917234 0.856 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr19_-_10869757 0.840 ENSMUST00000120524.1
ENSMUST00000025645.7
Tmem132a

transmembrane protein 132A

chr10_+_82954344 0.789 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr15_-_66286224 0.771 ENSMUST00000070256.7
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chr8_+_58912257 0.769 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr6_-_124415037 0.751 ENSMUST00000035861.5
ENSMUST00000112532.1
ENSMUST00000080557.5
Pex5


peroxisomal biogenesis factor 5


chr2_-_29253001 0.741 ENSMUST00000071201.4
Ntng2
netrin G2
chr7_-_105633525 0.639 ENSMUST00000153371.1
ENSMUST00000106789.1
ENSMUST00000057525.7
Trim3


tripartite motif-containing 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.6 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.3 1.4 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.4 1.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.1 GO:1903802 positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.1 1.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 0.8 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.8 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 0.5 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.1 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0043204 perikaryon(GO:0043204)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 1.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.3 1.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.0 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)