Motif ID: Zfp423
Z-value: 0.499
Transcription factors associated with Zfp423:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zfp423 | ENSMUSG00000045333.9 | Zfp423 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfp423 | mm10_v2_chr8_-_87804411_87804463 | 0.23 | 1.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.6 | GO:0097477 | lateral motor column neuron migration(GO:0097477) |
| 0.4 | 1.2 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.3 | 1.4 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.3 | 1.1 | GO:1903802 | positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123) |
| 0.3 | 0.8 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.2 | 0.5 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.2 | 0.5 | GO:0060129 | BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) |
| 0.1 | 0.4 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.1 | 1.0 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.1 | 0.5 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 0.1 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) |
| 0.1 | 0.8 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.1 | 0.3 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
| 0.0 | 0.3 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 0.0 | 0.3 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.0 | 0.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.1 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.0 | 0.9 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 0.3 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.0 | 0.3 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.0 | 0.3 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 0.1 | GO:0001661 | conditioned taste aversion(GO:0001661) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.1 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.2 | 0.5 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.1 | 0.4 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.1 | 1.3 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.1 | 0.3 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.5 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.8 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.1 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.0 | 0.8 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 0.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 2.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 1.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.1 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.3 | 1.2 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.2 | 1.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.2 | 0.8 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 0.4 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.1 | 0.3 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.1 | 0.5 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.1 | 1.1 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.9 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.1 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.0 | 0.3 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.0 | 0.8 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.3 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 1.0 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 0.1 | GO:0070905 | serine binding(GO:0070905) |
| 0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.0 | 0.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 0.0 | GO:0050827 | toxin receptor binding(GO:0050827) |
| 0.0 | 0.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.0 | 0.1 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
