Motif ID: Zfp691

Z-value: 0.392


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_119174221-0.241.8e-01Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_128601106 0.917 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr9_+_62858085 0.788 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chr7_+_28863831 0.543 ENSMUST00000138272.1
Lgals7
lectin, galactose binding, soluble 7
chr8_+_88521344 0.529 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr9_-_58202281 0.502 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr17_-_23684019 0.488 ENSMUST00000085989.5
Cldn9
claudin 9
chr8_+_72319033 0.457 ENSMUST00000067912.7
Klf2
Kruppel-like factor 2 (lung)
chr10_+_81183263 0.451 ENSMUST00000047665.6
Dapk3
death-associated protein kinase 3
chr10_-_77166545 0.426 ENSMUST00000081654.6
Col18a1
collagen, type XVIII, alpha 1
chr1_-_138856819 0.369 ENSMUST00000112025.1
2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr9_-_108452377 0.350 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr7_+_143069249 0.340 ENSMUST00000060433.3
ENSMUST00000133410.2
ENSMUST00000105920.1
ENSMUST00000177841.1
ENSMUST00000147995.1
ENSMUST00000137856.1
Tssc4





tumor-suppressing subchromosomal transferable fragment 4





chr2_+_26591423 0.333 ENSMUST00000152988.2
ENSMUST00000149789.1
Egfl7

EGF-like domain 7

chr10_+_115569986 0.323 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr11_-_75422586 0.316 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr1_+_51289106 0.310 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr7_-_45061706 0.303 ENSMUST00000107832.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr15_+_44196135 0.297 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr13_+_53525703 0.294 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr9_-_106887000 0.284 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr7_-_45061651 0.279 ENSMUST00000007981.3
ENSMUST00000107831.1
Prrg2

proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

chr3_-_33143025 0.265 ENSMUST00000108226.1
Pex5l
peroxisomal biogenesis factor 5-like
chr9_-_21067093 0.260 ENSMUST00000115494.2
Zglp1
zinc finger, GATA-like protein 1
chr6_+_134640940 0.260 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr2_-_10130638 0.258 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr3_-_92429403 0.253 ENSMUST00000047300.7
Gm9774
predicted pseudogene 9774
chr3_+_133338936 0.245 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr9_+_50603892 0.241 ENSMUST00000044051.4
Timm8b
translocase of inner mitochondrial membrane 8B
chr2_+_29802626 0.230 ENSMUST00000080065.2
Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr2_+_181715005 0.228 ENSMUST00000071585.3
ENSMUST00000148334.1
ENSMUST00000108763.1
Oprl1


opioid receptor-like 1


chr10_+_60003321 0.216 ENSMUST00000164083.2
Ascc1
activating signal cointegrator 1 complex subunit 1
chr8_-_124569696 0.216 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_-_33143227 0.209 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr10_+_81183000 0.208 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr13_-_60897439 0.203 ENSMUST00000171347.1
ENSMUST00000021884.8
Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr15_-_83555681 0.196 ENSMUST00000061882.8
Mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr1_+_134193432 0.178 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr19_+_11516473 0.177 ENSMUST00000163078.1
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr2_-_155729359 0.173 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr10_-_86732409 0.160 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr11_-_116694802 0.156 ENSMUST00000079545.5
St6galnac2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr6_+_28475101 0.154 ENSMUST00000168362.1
Snd1
staphylococcal nuclease and tudor domain containing 1
chr1_-_155146755 0.151 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr9_-_50603792 0.150 ENSMUST00000000175.4
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr10_-_112928974 0.150 ENSMUST00000099276.2
Atxn7l3b
ataxin 7-like 3B
chr4_+_126046903 0.146 ENSMUST00000030675.7
Mrps15
mitochondrial ribosomal protein S15
chr13_-_55528511 0.140 ENSMUST00000047877.4
Dok3
docking protein 3
chr8_+_123235086 0.139 ENSMUST00000181432.1
4933417D19Rik
RIKEN cDNA 4933417D19 gene
chr2_-_170194033 0.136 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr4_+_132535542 0.132 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
Dnajc8



DnaJ (Hsp40) homolog, subfamily C, member 8



chr13_+_55622999 0.132 ENSMUST00000021963.4
Caml
calcium modulating ligand
chr12_-_71136611 0.132 ENSMUST00000021486.8
ENSMUST00000166120.1
Timm9

translocase of inner mitochondrial membrane 9

chr4_-_129623870 0.130 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
Ccdc28b


coiled coil domain containing 28B


chr2_+_24962400 0.123 ENSMUST00000028351.3
Dph7
diphthamine biosynethesis 7
chr4_+_124714776 0.118 ENSMUST00000030734.4
Sf3a3
splicing factor 3a, subunit 3
chr4_+_129189760 0.114 ENSMUST00000106054.2
ENSMUST00000001365.2
Yars

tyrosyl-tRNA synthetase

chr8_+_3621529 0.114 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr6_-_34878006 0.109 ENSMUST00000115006.1
ENSMUST00000055097.4
ENSMUST00000115007.2
3110062M04Rik


RIKEN cDNA 3110062M04 gene


chr2_-_130664565 0.106 ENSMUST00000089559.4
Ddrgk1
DDRGK domain containing 1
chrX_-_101268218 0.103 ENSMUST00000033664.7
Il2rg
interleukin 2 receptor, gamma chain
chr3_-_67515487 0.101 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr8_+_69808672 0.100 ENSMUST00000036074.8
ENSMUST00000123453.1
Gmip

Gem-interacting protein

chr3_-_62605140 0.099 ENSMUST00000058535.5
Gpr149
G protein-coupled receptor 149
chr13_-_100786402 0.099 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr10_-_81183849 0.085 ENSMUST00000056086.4
4930442H23Rik
RIKEN cDNA 4930442H23 gene
chr15_-_76723814 0.079 ENSMUST00000036247.8
C030006K11Rik
RIKEN cDNA C030006K11 gene
chr10_-_60003056 0.077 ENSMUST00000182912.1
ENSMUST00000020307.4
ENSMUST00000182898.1
Anapc16


anaphase promoting complex subunit 16


chr13_-_54468805 0.071 ENSMUST00000026990.5
Thoc3
THO complex 3
chr5_+_95956916 0.071 ENSMUST00000023840.5
Cxcl13
chemokine (C-X-C motif) ligand 13
chr6_+_88465409 0.069 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chr17_-_65772686 0.069 ENSMUST00000070673.7
Rab31
RAB31, member RAS oncogene family
chr5_-_130003000 0.069 ENSMUST00000026613.7
Gusb
glucuronidase, beta
chr7_-_38019505 0.068 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr2_+_119112793 0.066 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr8_-_77517898 0.066 ENSMUST00000076316.4
Arhgap10
Rho GTPase activating protein 10
chr11_-_6626030 0.065 ENSMUST00000000394.7
ENSMUST00000136682.1
Tbrg4

transforming growth factor beta regulated gene 4

chr14_-_20348040 0.065 ENSMUST00000022344.2
Ecd
ecdysoneless homolog (Drosophila)
chr10_-_60002993 0.060 ENSMUST00000182116.1
Anapc16
anaphase promoting complex subunit 16
chr10_-_93891141 0.055 ENSMUST00000180840.1
Metap2
methionine aminopeptidase 2
chr9_+_50617516 0.053 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr15_-_12592556 0.049 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr9_-_103761820 0.048 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr10_+_94576254 0.048 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr16_+_32608920 0.048 ENSMUST00000023486.8
Tfrc
transferrin receptor
chr5_+_129908538 0.039 ENSMUST00000178355.1
Nupr1l
nuclear protein transcriptional regulator 1 like
chr2_+_181497223 0.037 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr12_+_102129019 0.037 ENSMUST00000079020.4
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr11_-_120467414 0.035 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr9_-_50617428 0.033 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823

expressed sequence AU019823

chr2_-_130284422 0.033 ENSMUST00000028892.4
Idh3b
isocitrate dehydrogenase 3 (NAD+) beta
chr6_-_24515036 0.031 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr15_+_97784355 0.025 ENSMUST00000117892.1
Slc48a1
solute carrier family 48 (heme transporter), member 1
chr14_+_20348159 0.024 ENSMUST00000090503.4
ENSMUST00000090499.5
ENSMUST00000037698.5
ENSMUST00000051915.6
Fam149b



family with sequence similarity 149, member B



chr7_-_105737376 0.023 ENSMUST00000098148.4
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr13_-_34130345 0.023 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr16_+_90386382 0.018 ENSMUST00000065856.6
Hunk
hormonally upregulated Neu-associated kinase
chr8_+_72135247 0.010 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr18_-_56975333 0.007 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr5_+_35893319 0.002 ENSMUST00000064571.4
Afap1
actin filament associated protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 0.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 1.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.5 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.2 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.1 0.5 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.2 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.2 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.1 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0008932 lytic endotransglycosylase activity(GO:0008932)