Motif ID: Zic2

Z-value: 0.580


Transcription factors associated with Zic2:

Gene SymbolEntrez IDGene Name
Zic2 ENSMUSG00000061524.8 Zic2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic2mm10_v2_chr14_+_122475397_1224754350.345.5e-02Click!


Activity profile for motif Zic2.

activity profile for motif Zic2


Sorted Z-values histogram for motif Zic2

Sorted Z-values for motif Zic2



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_19699008 3.496 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr7_-_19698206 1.820 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr7_-_19698383 1.693 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr6_-_115251839 1.536 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr14_+_27039001 1.519 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr8_+_80494032 1.373 ENSMUST00000063359.6
Gypa
glycophorin A
chr7_+_117380937 1.254 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr10_+_125966214 1.210 ENSMUST00000074807.6
Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
chr2_-_122611238 1.188 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr14_+_19751257 1.162 ENSMUST00000022340.3
Nid2
nidogen 2
chr5_-_70842617 1.153 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr4_-_41503046 1.131 ENSMUST00000054920.4
AI464131
expressed sequence AI464131
chr1_+_9547948 1.086 ENSMUST00000144177.1
Adhfe1
alcohol dehydrogenase, iron containing, 1
chr4_+_42240639 1.079 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr15_-_8710409 1.071 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_63128973 1.039 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr16_-_10313940 1.026 ENSMUST00000078357.4
Emp2
epithelial membrane protein 2
chr11_-_68386974 1.020 ENSMUST00000135141.1
Ntn1
netrin 1
chr12_-_56536895 0.971 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr5_-_92278155 0.916 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr14_-_26170283 0.902 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr11_+_51289920 0.887 ENSMUST00000102765.2
Col23a1
collagen, type XXIII, alpha 1
chr5_-_148392810 0.880 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr9_+_104002546 0.862 ENSMUST00000035167.8
ENSMUST00000117054.1
Nphp3

nephronophthisis 3 (adolescent)

chr5_+_105519388 0.853 ENSMUST00000067924.6
ENSMUST00000150981.1
Lrrc8c

leucine rich repeat containing 8 family, member C

chr17_+_86963077 0.853 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr17_+_86963279 0.832 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr8_+_31187317 0.826 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr10_+_62071014 0.826 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr11_+_121702591 0.788 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr2_-_35336969 0.786 ENSMUST00000028241.6
Stom
stomatin
chr15_+_25773985 0.784 ENSMUST00000125667.1
Myo10
myosin X
chr1_-_153332724 0.758 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr11_+_5861886 0.755 ENSMUST00000102923.3
Aebp1
AE binding protein 1
chr11_-_102946688 0.748 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr4_+_42091207 0.722 ENSMUST00000178882.1
Gm3893
predicted gene 3893
chr2_-_180225812 0.722 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr4_-_143299463 0.702 ENSMUST00000119654.1
Pdpn
podoplanin
chr11_+_105292637 0.699 ENSMUST00000100335.3
ENSMUST00000021038.4
Mrc2

mannose receptor, C type 2

chr13_+_58806564 0.688 ENSMUST00000109838.2
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr11_-_12026237 0.687 ENSMUST00000150972.1
Grb10
growth factor receptor bound protein 10
chr8_+_94179089 0.679 ENSMUST00000034215.6
Mt1
metallothionein 1
chr8_+_92827273 0.677 ENSMUST00000034187.7
Mmp2
matrix metallopeptidase 2
chr11_-_12026732 0.670 ENSMUST00000143915.1
Grb10
growth factor receptor bound protein 10
chr3_+_117575268 0.660 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr8_-_104395765 0.653 ENSMUST00000179802.1
Cmtm4
CKLF-like MARVEL transmembrane domain containing 4
chr4_-_96591555 0.647 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr12_+_76417598 0.638 ENSMUST00000063977.7
Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr12_-_80260091 0.636 ENSMUST00000167327.1
Actn1
actinin, alpha 1
chr17_+_32685610 0.631 ENSMUST00000168171.1
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr4_-_143299498 0.629 ENSMUST00000030317.7
Pdpn
podoplanin
chr10_+_67979592 0.623 ENSMUST00000105437.1
Rtkn2
rhotekin 2
chr7_+_35119285 0.621 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr10_+_67979569 0.621 ENSMUST00000118160.1
Rtkn2
rhotekin 2
chr5_+_108694222 0.617 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr4_-_58987095 0.613 ENSMUST00000030069.6
Ptgr1
prostaglandin reductase 1
chr5_+_140607334 0.606 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_152754156 0.597 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr1_+_74661794 0.595 ENSMUST00000129890.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr3_+_117575227 0.591 ENSMUST00000106473.2
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr7_-_142666816 0.582 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr3_+_154597352 0.579 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
Cryz


crystallin, zeta


chr15_+_85205949 0.574 ENSMUST00000057410.7
ENSMUST00000109432.3
Fbln1

fibulin 1

chr10_-_121626316 0.573 ENSMUST00000039810.7
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr19_-_10101501 0.571 ENSMUST00000025567.7
Fads2
fatty acid desaturase 2
chr17_-_27022786 0.565 ENSMUST00000143158.1
Bak1
BCL2-antagonist/killer 1
chr8_+_12395287 0.560 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr2_-_93452679 0.560 ENSMUST00000111257.1
ENSMUST00000145553.1
Cd82

CD82 antigen

chr13_-_70841790 0.558 ENSMUST00000080145.6
ENSMUST00000109694.2
Adamts16

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16

chr15_-_78405824 0.546 ENSMUST00000058659.7
Tst
thiosulfate sulfurtransferase, mitochondrial
chr3_+_135485605 0.546 ENSMUST00000029814.9
Manba
mannosidase, beta A, lysosomal
chr12_+_81026800 0.542 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr7_-_19665005 0.540 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr11_-_100414829 0.540 ENSMUST00000066489.6
Leprel4
leprecan-like 4
chr10_+_76253848 0.540 ENSMUST00000036387.7
S100b
S100 protein, beta polypeptide, neural
chr16_-_11254161 0.537 ENSMUST00000080030.7
Gspt1
G1 to S phase transition 1
chr16_-_28929658 0.535 ENSMUST00000100023.1
Mb21d2
Mab-21 domain containing 2
chr11_+_53770014 0.535 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr16_+_35983424 0.534 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr10_-_42583628 0.528 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr14_-_57664954 0.528 ENSMUST00000089482.5
Xpo4
exportin 4
chr3_+_131110350 0.528 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr9_-_60838200 0.527 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chr10_+_99108135 0.527 ENSMUST00000161240.2
Galnt4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4
chr13_+_52596847 0.522 ENSMUST00000055087.6
Syk
spleen tyrosine kinase
chr3_+_154597197 0.509 ENSMUST00000155385.1
ENSMUST00000029850.8
Cryz

crystallin, zeta

chr11_-_119355484 0.506 ENSMUST00000100172.2
ENSMUST00000005173.4
Sgsh

N-sulfoglucosamine sulfohydrolase (sulfamidase)

chr9_-_67539392 0.500 ENSMUST00000039662.8
Tln2
talin 2
chr5_+_92603039 0.498 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr1_-_128359610 0.496 ENSMUST00000027601.4
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr2_-_25470031 0.490 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr19_-_3929723 0.489 ENSMUST00000051803.6
Aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr11_-_117780630 0.486 ENSMUST00000026659.3
ENSMUST00000127227.1
Tmc6

transmembrane channel-like gene family 6

chr12_-_104865076 0.484 ENSMUST00000109937.1
ENSMUST00000109936.1
Clmn

calmin

chr17_+_32685655 0.484 ENSMUST00000008801.6
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr2_+_32646586 0.483 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr19_-_4439388 0.481 ENSMUST00000117462.1
ENSMUST00000048197.3
Rhod

ras homolog gene family, member D

chr7_+_79053483 0.477 ENSMUST00000032835.5
Acan
aggrecan
chr10_+_67979709 0.474 ENSMUST00000117086.1
Rtkn2
rhotekin 2
chr6_+_65671590 0.473 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr2_-_25469742 0.472 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr2_-_75704535 0.467 ENSMUST00000102672.4
Nfe2l2
nuclear factor, erythroid derived 2, like 2
chr15_+_6422240 0.465 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr2_+_150786735 0.461 ENSMUST00000045441.7
Pygb
brain glycogen phosphorylase
chr4_+_136172367 0.456 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr11_-_6475992 0.454 ENSMUST00000179343.1
Purb
purine rich element binding protein B
chr19_-_55099417 0.452 ENSMUST00000061856.5
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr4_+_137913471 0.449 ENSMUST00000151110.1
Ece1
endothelin converting enzyme 1
chr11_+_94327984 0.449 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr11_-_71004387 0.445 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33

DEAH (Asp-Glu-Ala-His) box polypeptide 33

chr19_+_46573362 0.445 ENSMUST00000026011.6
Sfxn2
sideroflexin 2
chr2_-_26604267 0.439 ENSMUST00000028286.5
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr4_-_134704235 0.438 ENSMUST00000054096.6
ENSMUST00000038628.3
Man1c1

mannosidase, alpha, class 1C, member 1

chr9_+_110344185 0.435 ENSMUST00000142100.1
Scap
SREBF chaperone
chr8_-_105471481 0.435 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr14_-_122465677 0.434 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr9_+_107576915 0.430 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr10_+_80016901 0.428 ENSMUST00000105373.1
Hmha1
histocompatibility (minor) HA-1
chr16_+_4639941 0.414 ENSMUST00000038770.3
Vasn
vasorin
chr14_-_31206666 0.410 ENSMUST00000165981.1
ENSMUST00000171735.1
Nisch

nischarin

chr1_-_125912160 0.406 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr19_-_18631754 0.398 ENSMUST00000025631.6
Ostf1
osteoclast stimulating factor 1
chr5_+_92897981 0.397 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr3_-_153725062 0.395 ENSMUST00000064460.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr3_+_66985680 0.387 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr14_-_67933512 0.387 ENSMUST00000039135.4
Dock5
dedicator of cytokinesis 5
chr10_-_13474361 0.386 ENSMUST00000105547.1
Phactr2
phosphatase and actin regulator 2
chr7_+_121707189 0.385 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr8_-_36613937 0.384 ENSMUST00000033923.7
Dlc1
deleted in liver cancer 1
chr10_-_61452658 0.375 ENSMUST00000167087.1
ENSMUST00000020288.7
Eif4ebp2

eukaryotic translation initiation factor 4E binding protein 2

chr5_+_137288273 0.374 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr3_+_66985647 0.374 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr10_-_78295394 0.369 ENSMUST00000105387.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr13_+_44731281 0.368 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr12_-_80260356 0.363 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr5_+_110839973 0.363 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr17_+_47737030 0.363 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr3_+_66985700 0.355 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr7_-_79842287 0.354 ENSMUST00000049004.6
Anpep
alanyl (membrane) aminopeptidase
chr4_+_62286441 0.351 ENSMUST00000084530.2
Slc31a2
solute carrier family 31, member 2
chr4_+_20042046 0.349 ENSMUST00000098242.3
Ggh
gamma-glutamyl hydrolase
chr8_+_124023394 0.348 ENSMUST00000034457.8
Urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr3_+_121291725 0.345 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr7_-_44997221 0.341 ENSMUST00000152341.1
Bcl2l12
BCL2-like 12 (proline rich)
chr17_+_28769307 0.340 ENSMUST00000004986.6
Mapk13
mitogen-activated protein kinase 13
chr11_-_60220550 0.339 ENSMUST00000020846.1
Srebf1
sterol regulatory element binding transcription factor 1
chr11_-_90638062 0.337 ENSMUST00000020858.7
ENSMUST00000107875.1
ENSMUST00000107872.1
ENSMUST00000143203.1
Stxbp4



syntaxin binding protein 4



chr18_-_61786636 0.334 ENSMUST00000120472.1
Afap1l1
actin filament associated protein 1-like 1
chr5_+_139423151 0.332 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr15_+_102102926 0.330 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr6_-_35308110 0.329 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr5_+_92683625 0.328 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr8_-_22398588 0.322 ENSMUST00000033871.6
Slc25a15
solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15
chr12_+_84100654 0.321 ENSMUST00000056822.3
Acot6
acyl-CoA thioesterase 6
chr13_+_49187485 0.320 ENSMUST00000049022.8
ENSMUST00000120733.1
Ninj1

ninjurin 1

chr11_+_87578384 0.319 ENSMUST00000107962.1
ENSMUST00000122067.1
Sept4

septin 4

chr9_+_14860210 0.318 ENSMUST00000034408.5
ENSMUST00000115624.2
Gpr83

G protein-coupled receptor 83

chr5_-_100820929 0.318 ENSMUST00000117364.1
ENSMUST00000055245.6
Fam175a

family with sequence similarity 175, member A

chrX_-_7967817 0.317 ENSMUST00000033502.7
Gata1
GATA binding protein 1
chr7_+_79660196 0.317 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr5_+_43662373 0.315 ENSMUST00000048150.8
Cc2d2a
coiled-coil and C2 domain containing 2A
chr1_+_74661714 0.314 ENSMUST00000042125.8
ENSMUST00000141119.1
Ttll4

tubulin tyrosine ligase-like family, member 4

chr13_+_34037619 0.313 ENSMUST00000040656.6
Bphl
biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)
chr10_+_40629987 0.313 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr16_-_11254268 0.313 ENSMUST00000167571.1
Gspt1
G1 to S phase transition 1
chr4_-_149137536 0.304 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
Apitd1



apoptosis-inducing, TAF9-like domain 1



chr4_-_139832920 0.304 ENSMUST00000174681.1
Pax7
paired box gene 7
chrX_+_75382384 0.303 ENSMUST00000033541.4
Fundc2
FUN14 domain containing 2
chr4_+_47208005 0.299 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chr2_-_38287174 0.299 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr7_+_28810886 0.297 ENSMUST00000038572.8
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr1_+_91366412 0.295 ENSMUST00000086861.5
Fam132b
family with sequence similarity 132, member B
chr17_+_91088493 0.295 ENSMUST00000095183.1
Gm10308
predicted gene 10308
chr7_-_16476765 0.294 ENSMUST00000002053.8
Npas1
neuronal PAS domain protein 1
chr7_+_120842824 0.294 ENSMUST00000047875.8
Eef2k
eukaryotic elongation factor-2 kinase
chrX_+_120290259 0.294 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
Pcdh11x


protocadherin 11 X-linked


chr2_-_33640480 0.291 ENSMUST00000176067.1
ENSMUST00000041730.4
Lmx1b

LIM homeobox transcription factor 1 beta

chr8_+_46490968 0.290 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr2_+_31572775 0.287 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr7_-_109986250 0.286 ENSMUST00000119929.1
Tmem41b
transmembrane protein 41B
chrX_+_73639414 0.286 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr19_+_8664005 0.285 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr13_+_55727345 0.284 ENSMUST00000124968.1
ENSMUST00000021958.5
Pcbd2

pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2

chr7_-_44997535 0.284 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr15_-_50889043 0.279 ENSMUST00000183997.1
ENSMUST00000183757.1
Trps1

trichorhinophalangeal syndrome I (human)

chr10_+_60106198 0.277 ENSMUST00000121820.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr2_+_31950257 0.277 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr10_+_11343387 0.276 ENSMUST00000069106.4
Epm2a
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr10_-_77113676 0.275 ENSMUST00000072755.4
ENSMUST00000105409.1
Col18a1

collagen, type XVIII, alpha 1

chr8_+_78509319 0.270 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr4_+_126556994 0.269 ENSMUST00000147675.1
Clspn
claspin
chr7_+_28810928 0.268 ENSMUST00000174477.1
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr19_-_31664356 0.267 ENSMUST00000073581.5
Prkg1
protein kinase, cGMP-dependent, type I
chr7_+_25221417 0.267 ENSMUST00000055604.4
Zfp526
zinc finger protein 526
chr7_-_19921139 0.266 ENSMUST00000043517.7
Pvr
poliovirus receptor
chr7_+_122289297 0.264 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr1_-_71103146 0.264 ENSMUST00000027393.7
Bard1
BRCA1 associated RING domain 1
chr9_+_53771499 0.259 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr17_-_45572495 0.258 ENSMUST00000130406.1
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr2_+_31572701 0.257 ENSMUST00000055244.6
Fubp3
far upstream element (FUSE) binding protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.4 1.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.4 1.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.3 1.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.3 1.0 GO:0021759 globus pallidus development(GO:0021759)
0.3 1.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 0.9 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 0.8 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 1.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.7 GO:0061743 motor learning(GO:0061743)
0.2 1.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.6 GO:0051031 tRNA transport(GO:0051031)
0.2 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.6 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2 0.5 GO:0035928 RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
0.2 0.5 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 0.5 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895)
0.2 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 0.5 GO:0002554 serotonin secretion by platelet(GO:0002554) interleukin-3 production(GO:0032632) beta selection(GO:0043366)
0.2 0.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 0.5 GO:1902037 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 0.6 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.9 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1 0.4 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 1.4 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 0.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 2.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.6 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.3 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.1 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0021764 amygdala development(GO:0021764)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 0.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:0046959 habituation(GO:0046959)
0.1 1.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.4 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.1 0.3 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
0.1 1.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.1 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.6 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 0.3 GO:0030222 eosinophil differentiation(GO:0030222)
0.1 0.6 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.1 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.5 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 0.1 GO:0015819 lysine transport(GO:0015819)
0.1 1.2 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.6 GO:0060539 diaphragm development(GO:0060539)
0.1 0.8 GO:0036065 fucosylation(GO:0036065)
0.1 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.6 GO:0009650 UV protection(GO:0009650)
0.1 0.3 GO:1903887 motile primary cilium assembly(GO:1903887) protein localization to ciliary transition zone(GO:1904491)
0.1 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:0051775 response to redox state(GO:0051775)
0.1 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.2 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.1 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.0 0.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.4 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.3 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110) regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.2 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.4 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0046464 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.5 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:1901621 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0021747 cochlear nucleus development(GO:0021747)
0.0 0.1 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.1 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.5 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.2 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754) regulation of vascular wound healing(GO:0061043)
0.0 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.0 GO:0002606 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.0 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.0 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:1903624 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0072600 establishment of protein localization to Golgi(GO:0072600)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 0.9 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 0.8 GO:0018444 translation release factor complex(GO:0018444)
0.2 1.0 GO:0032127 dense core granule membrane(GO:0032127)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 0.6 GO:0071953 fibrinogen complex(GO:0005577) elastic fiber(GO:0071953)
0.2 0.3 GO:0016234 inclusion body(GO:0016234)
0.2 0.7 GO:0043259 laminin-10 complex(GO:0043259)
0.2 0.5 GO:0072534 perineuronal net(GO:0072534)
0.2 0.6 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.7 GO:0044301 climbing fiber(GO:0044301)
0.1 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.3 GO:0097227 sperm annulus(GO:0097227)
0.1 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.2 GO:0043205 fibril(GO:0043205)
0.1 1.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.5 GO:0005916 fascia adherens(GO:0005916)
0.1 0.7 GO:0046930 pore complex(GO:0046930)
0.1 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 1.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 3.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0030120 vesicle coat(GO:0030120)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 1.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 3.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 3.3 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 1.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 1.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 1.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.6 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.2 1.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 0.5 GO:0005534 galactose binding(GO:0005534)
0.2 0.8 GO:2001070 starch binding(GO:2001070)
0.2 0.6 GO:0016631 enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.2 0.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.9 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.6 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.3 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.1 0.1 GO:0015189 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.5 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.4 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.1 0.3 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 0.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922)
0.1 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.6 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.2 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 0.4 GO:0000182 rDNA binding(GO:0000182)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 1.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0070402 NADPH binding(GO:0070402)
0.1 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) oligo-1,6-glucosidase activity(GO:0004574) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.4 GO:0032564 dATP binding(GO:0032564)
0.0 0.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.0 1.2 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.9 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) [methionine synthase] reductase activity(GO:0030586) iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.0 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0020037 heme binding(GO:0020037)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0016208 AMP binding(GO:0016208)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0 1.6 GO:0051015 actin filament binding(GO:0051015)