Motif ID: Zic4

Z-value: 0.839


Transcription factors associated with Zic4:

Gene SymbolEntrez IDGene Name
Zic4 ENSMUSG00000036972.8 Zic4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic4mm10_v2_chr9_+_91368811_913688280.222.1e-01Click!


Activity profile for motif Zic4.

activity profile for motif Zic4


Sorted Z-values histogram for motif Zic4

Sorted Z-values for motif Zic4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_115251839 2.941 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr11_-_102946688 2.859 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr12_-_56535047 2.835 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr6_+_141524379 2.775 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr1_+_91179822 2.695 ENSMUST00000097648.4
ENSMUST00000165855.1
Ramp1

receptor (calcitonin) activity modifying protein 1

chr17_-_71310952 2.403 ENSMUST00000024849.9
Emilin2
elastin microfibril interfacer 2
chr19_-_57008187 2.285 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr11_+_5861886 2.163 ENSMUST00000102923.3
Aebp1
AE binding protein 1
chr2_+_147187424 2.008 ENSMUST00000144411.1
6430503K07Rik
RIKEN cDNA 6430503K07 gene
chr17_+_79051906 1.921 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr3_-_107986408 1.770 ENSMUST00000012348.2
Gstm2
glutathione S-transferase, mu 2
chr3_-_107986360 1.746 ENSMUST00000066530.6
Gstm2
glutathione S-transferase, mu 2
chr2_+_85136355 1.694 ENSMUST00000057019.7
Aplnr
apelin receptor
chr4_-_64046925 1.692 ENSMUST00000107377.3
Tnc
tenascin C
chrX_-_49797700 1.675 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1

immunoglobulin superfamily, member 1

chr13_-_95223045 1.596 ENSMUST00000162292.1
Pde8b
phosphodiesterase 8B
chr11_-_6475992 1.595 ENSMUST00000179343.1
Purb
purine rich element binding protein B
chr18_-_80713062 1.558 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr11_+_121702591 1.525 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr4_-_57143437 1.510 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr2_+_32535315 1.495 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr2_-_152951547 1.432 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chr2_-_152951456 1.361 ENSMUST00000123121.2
Dusp15
dual specificity phosphatase-like 15
chr2_-_152951688 1.326 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr2_+_32535724 1.325 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr19_+_48206025 1.273 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr14_+_25980039 1.262 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr14_+_26119811 1.247 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr7_+_139834148 1.203 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr11_+_61956779 1.189 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr14_+_26259109 1.166 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr19_+_4855129 1.163 ENSMUST00000119694.1
Ctsf
cathepsin F
chr2_+_180598219 1.141 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr7_-_16476765 1.055 ENSMUST00000002053.8
Npas1
neuronal PAS domain protein 1
chr18_+_58836721 1.046 ENSMUST00000052907.5
Adamts19
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
chr6_-_35308110 1.032 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr4_+_117096049 1.026 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr19_+_4099998 1.004 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr3_+_107595031 1.000 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr15_+_7129557 0.975 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chrX_-_107403295 0.935 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr5_-_24527276 0.923 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr3_-_95015416 0.917 ENSMUST00000132195.1
Zfp687
zinc finger protein 687
chr6_+_65671590 0.909 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr4_-_11386757 0.905 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr19_-_12501996 0.876 ENSMUST00000045521.7
Dtx4
deltex 4 homolog (Drosophila)
chr17_-_85688252 0.840 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr14_-_52316323 0.803 ENSMUST00000135523.1
Sall2
sal-like 2 (Drosophila)
chr3_-_95015214 0.801 ENSMUST00000128438.1
ENSMUST00000149747.1
ENSMUST00000019482.1
Zfp687


zinc finger protein 687


chr8_-_64693027 0.798 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr9_+_46012810 0.794 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr11_-_59290746 0.792 ENSMUST00000010044.7
Wnt3a
wingless-related MMTV integration site 3A
chr16_+_16213318 0.781 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr2_+_119325784 0.777 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chr8_-_45382198 0.750 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr9_+_46012822 0.735 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr6_-_39118211 0.729 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr3_-_110142996 0.729 ENSMUST00000156177.2
Ntng1
netrin G1
chr3_+_59006978 0.710 ENSMUST00000040325.7
ENSMUST00000164225.1
ENSMUST00000040846.8
ENSMUST00000029393.8
Med12l



mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like



chr3_+_61002786 0.684 ENSMUST00000029331.1
P2ry1
purinergic receptor P2Y, G-protein coupled 1
chr2_+_120977017 0.682 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr11_-_116335384 0.671 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr12_+_24651346 0.665 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr4_-_56865135 0.639 ENSMUST00000107612.2
ENSMUST00000045142.8
Ctnnal1

catenin (cadherin associated protein), alpha-like 1

chr5_-_125341043 0.638 ENSMUST00000111390.1
ENSMUST00000086075.6
Scarb1

scavenger receptor class B, member 1

chr2_+_91922178 0.635 ENSMUST00000170432.1
Chrm4
cholinergic receptor, muscarinic 4
chr17_-_34031684 0.633 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr7_+_27591705 0.630 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr11_-_69920892 0.624 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr8_-_111393810 0.621 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr17_-_34031644 0.599 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr16_+_35983424 0.589 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr7_+_98703091 0.577 ENSMUST00000033009.9
Prkrir
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr4_-_133602168 0.574 ENSMUST00000057311.3
Sfn
stratifin
chr9_+_62838767 0.530 ENSMUST00000034776.6
Cln6
ceroid-lipofuscinosis, neuronal 6
chr9_-_29412204 0.524 ENSMUST00000115237.1
Ntm
neurotrimin
chr17_-_51179249 0.492 ENSMUST00000024717.8
Tbc1d5
TBC1 domain family, member 5
chr4_+_128883549 0.473 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr17_-_57059795 0.473 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr4_-_151996113 0.465 ENSMUST00000055688.9
Phf13
PHD finger protein 13
chr5_-_113310729 0.444 ENSMUST00000112325.1
ENSMUST00000048112.6
Sgsm1

small G protein signaling modulator 1

chr4_-_156197479 0.440 ENSMUST00000075787.6
ENSMUST00000180572.1
Agrn

agrin

chr7_+_27591513 0.436 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr17_-_34031544 0.434 ENSMUST00000025186.8
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr4_+_148130883 0.413 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr3_-_8964037 0.409 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr2_-_181288016 0.406 ENSMUST00000049032.6
Gmeb2
glucocorticoid modulatory element binding protein 2
chr10_+_127739516 0.394 ENSMUST00000054287.7
Zbtb39
zinc finger and BTB domain containing 39
chr12_-_67222549 0.387 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr10_+_45335751 0.382 ENSMUST00000095715.3
Bves
blood vessel epicardial substance
chr13_-_95891905 0.370 ENSMUST00000068603.6
Iqgap2
IQ motif containing GTPase activating protein 2
chr9_-_63146980 0.367 ENSMUST00000055281.7
ENSMUST00000119146.1
Skor1

SKI family transcriptional corepressor 1

chr7_+_28766747 0.362 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr19_+_47178820 0.352 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr2_+_164879358 0.352 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr16_+_20733104 0.349 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr1_-_43163891 0.345 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr10_-_117845935 0.344 ENSMUST00000064667.7
Rap1b
RAS related protein 1b
chr4_-_24851079 0.342 ENSMUST00000084781.5
ENSMUST00000108218.3
Klhl32

kelch-like 32

chr6_+_29433248 0.319 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr8_-_116732991 0.319 ENSMUST00000109102.2
Cdyl2
chromodomain protein, Y chromosome-like 2
chr5_-_113310697 0.316 ENSMUST00000154248.1
Sgsm1
small G protein signaling modulator 1
chr2_-_71367749 0.315 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr4_+_130792513 0.306 ENSMUST00000070478.3
Sdc3
syndecan 3
chrX_+_42149534 0.306 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr19_-_4477447 0.305 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr12_+_102128718 0.305 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_-_83054415 0.302 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr1_+_153665666 0.301 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr13_-_37994111 0.300 ENSMUST00000021864.6
Ssr1
signal sequence receptor, alpha
chr16_+_14361552 0.294 ENSMUST00000100167.3
ENSMUST00000154748.1
ENSMUST00000134776.1
Abcc1


ATP-binding cassette, sub-family C (CFTR/MRP), member 1


chr11_+_93996082 0.283 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr1_+_153665627 0.280 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr7_-_100932140 0.250 ENSMUST00000107032.1
Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr5_+_43233463 0.250 ENSMUST00000169035.1
ENSMUST00000166713.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr8_-_87959560 0.248 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr8_-_36613937 0.245 ENSMUST00000033923.7
Dlc1
deleted in liver cancer 1
chr7_-_57387172 0.241 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chrX_+_159988433 0.235 ENSMUST00000033665.8
Map3k15
mitogen-activated protein kinase kinase kinase 15
chr6_+_97807014 0.231 ENSMUST00000043637.7
Mitf
microphthalmia-associated transcription factor
chr16_+_84835070 0.227 ENSMUST00000009120.7
Gabpa
GA repeat binding protein, alpha
chr2_+_131909928 0.222 ENSMUST00000091288.6
Prnp
prion protein
chr17_-_29237759 0.217 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr13_-_48625571 0.214 ENSMUST00000035824.9
Ptpdc1
protein tyrosine phosphatase domain containing 1
chr7_-_47133395 0.207 ENSMUST00000107617.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr4_+_62360695 0.206 ENSMUST00000084526.5
Slc31a1
solute carrier family 31, member 1
chr7_+_45873127 0.203 ENSMUST00000107718.1
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr15_+_74563738 0.203 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr2_+_131909951 0.200 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr4_-_62360524 0.180 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr13_+_15463202 0.178 ENSMUST00000130065.1
Gli3
GLI-Kruppel family member GLI3
chr11_-_101171302 0.177 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr11_+_75733037 0.174 ENSMUST00000131398.1
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr6_+_29433131 0.172 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr5_-_139325616 0.171 ENSMUST00000110865.1
Adap1
ArfGAP with dual PH domains 1
chr11_-_89538556 0.170 ENSMUST00000169201.1
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr12_+_3807017 0.163 ENSMUST00000020991.8
ENSMUST00000172509.1
Dnmt3a

DNA methyltransferase 3A

chr2_-_161109017 0.163 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr3_-_8667033 0.160 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr11_+_97663366 0.155 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_+_97658212 0.152 ENSMUST00000045743.6
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr4_-_62360436 0.150 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr9_-_89622986 0.146 ENSMUST00000044491.6
AF529169
cDNA sequence AF529169
chr1_+_153665274 0.143 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr4_+_109280365 0.140 ENSMUST00000177089.1
ENSMUST00000175776.1
ENSMUST00000132165.2
Eps15


epidermal growth factor receptor pathway substrate 15


chr14_-_54913089 0.126 ENSMUST00000050772.7
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr8_+_87472838 0.118 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr8_+_72240315 0.118 ENSMUST00000126885.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr11_+_75732869 0.112 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr1_+_153665587 0.103 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr7_+_45872772 0.101 ENSMUST00000002855.5
ENSMUST00000107719.1
Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr10_-_62792243 0.100 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr12_-_57546121 0.100 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr2_-_167062607 0.099 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr7_-_126503408 0.092 ENSMUST00000040202.8
Atxn2l
ataxin 2-like
chr8_+_87472805 0.085 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr18_-_24603464 0.078 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr2_-_130642770 0.075 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr9_-_67539392 0.069 ENSMUST00000039662.8
Tln2
talin 2
chrX_-_104671048 0.066 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr13_+_34037619 0.063 ENSMUST00000040656.6
Bphl
biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)
chr17_+_37045980 0.059 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_21961581 0.059 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr1_+_10039762 0.056 ENSMUST00000122156.1
ENSMUST00000118263.1
ENSMUST00000119714.1
Cspp1


centrosome and spindle pole associated protein 1


chr15_-_75909319 0.050 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr5_+_24426831 0.050 ENSMUST00000155598.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr15_-_36608959 0.048 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr2_-_167661496 0.045 ENSMUST00000125544.2
ENSMUST00000006587.6
Gm20431
Tmem189
predicted gene 20431
transmembrane protein 189
chr1_+_75546449 0.043 ENSMUST00000150142.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr7_-_97579382 0.041 ENSMUST00000151840.1
ENSMUST00000135998.1
ENSMUST00000144858.1
ENSMUST00000146605.1
ENSMUST00000072725.5
ENSMUST00000138060.1
ENSMUST00000154853.1
ENSMUST00000136757.1
ENSMUST00000124552.1
Aamdc








adipogenesis associated Mth938 domain containing








chr11_-_70669283 0.028 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7

sperm associated antigen 7

chr19_+_3767953 0.025 ENSMUST00000113970.1
Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr15_-_75909543 0.025 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr16_-_30388530 0.024 ENSMUST00000100013.2
ENSMUST00000061350.6
Atp13a3

ATPase type 13A3

chr2_-_154569845 0.022 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr18_+_34777008 0.022 ENSMUST00000043775.7
Kdm3b
KDM3B lysine (K)-specific demethylase 3B
chr17_-_26508463 0.020 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr11_+_77515104 0.020 ENSMUST00000094004.4
Abhd15
abhydrolase domain containing 15
chr7_+_45570342 0.009 ENSMUST00000120864.1
Bcat2
branched chain aminotransferase 2, mitochondrial
chr3_-_109027600 0.006 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chr3_-_20035285 0.005 ENSMUST00000108321.1
ENSMUST00000012580.6
Hps3

Hermansky-Pudlak syndrome 3 homolog (human)

chr17_+_37045963 0.003 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_115536181 0.003 ENSMUST00000118155.1
ENSMUST00000153892.1
Sumo2

SMT3 suppressor of mif two 3 homolog 2 (yeast)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0061743 motor learning(GO:0061743)
0.9 2.8 GO:0021759 globus pallidus development(GO:0021759)
0.8 0.8 GO:0072554 blood vessel lumenization(GO:0072554)
0.6 1.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.6 2.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 2.7 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.5 1.6 GO:0035106 operant conditioning(GO:0035106)
0.5 1.6 GO:0060854 patterning of lymph vessels(GO:0060854)
0.5 1.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.5 3.5 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.4 1.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.4 0.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.3 1.0 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.3 1.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.3 1.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.3 2.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 0.8 GO:0030070 insulin processing(GO:0030070)
0.3 0.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of heart induction(GO:0090381) negative regulation of dopaminergic neuron differentiation(GO:1904339) regulation of cardiac cell fate specification(GO:2000043)
0.2 0.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 0.7 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.2 0.6 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.2 0.8 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.2 0.7 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.2 0.5 GO:0097274 urea homeostasis(GO:0097274)
0.2 0.9 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.3 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.9 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 2.6 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.1 0.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.7 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 1.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.4 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 1.1 GO:0042711 maternal behavior(GO:0042711)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.6 GO:0031424 keratinization(GO:0031424) establishment of skin barrier(GO:0061436)
0.1 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 1.3 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.2 GO:0035907 dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.1 0.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.4 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 1.5 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 1.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.5 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 3.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.5 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.0 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 1.3 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 1.7 GO:0007369 gastrulation(GO:0007369)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0044301 climbing fiber(GO:0044301)
0.3 1.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 0.8 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0033010 paranodal junction(GO:0033010)
0.1 0.8 GO:0030057 desmosome(GO:0030057)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 2.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 7.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 3.7 GO:0043235 receptor complex(GO:0043235)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 4.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.7 2.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.4 1.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 1.0 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.3 2.0 GO:0045545 syndecan binding(GO:0045545)
0.3 1.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.3 0.8 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 3.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 2.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 0.7 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.2 2.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 2.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.7 GO:0034711 inhibin binding(GO:0034711)
0.2 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.6 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 1.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 3.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562) oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 4.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.6 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0043023 GTPase inhibitor activity(GO:0005095) ribosomal large subunit binding(GO:0043023)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0016917 GABA receptor activity(GO:0016917)