Motif ID: Zkscan1

Z-value: 0.715


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.241.9e-01Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

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Top targets:


Showing 1 to 20 of 112 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_79164477 5.531 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr4_-_42168603 3.758 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr8_+_72646679 2.943 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr8_+_72646728 2.936 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr4_+_129960760 2.470 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr13_-_53473074 2.025 ENSMUST00000021922.8
Msx2
msh homeobox 2
chrX_-_49797700 1.892 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1

immunoglobulin superfamily, member 1

chr10_+_86300372 1.869 ENSMUST00000020234.7
Timp3
tissue inhibitor of metalloproteinase 3
chr5_-_28210022 1.843 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr5_-_70842617 1.841 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr2_-_27248335 1.796 ENSMUST00000139312.1
Sardh
sarcosine dehydrogenase
chr4_+_138972885 1.678 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
Tmco4


transmembrane and coiled-coil domains 4


chr11_-_109722214 1.587 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr12_-_72664759 1.573 ENSMUST00000021512.9
Dhrs7
dehydrogenase/reductase (SDR family) member 7
chr14_-_8309770 1.568 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr7_+_24370255 1.449 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr14_+_46832127 1.415 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr3_+_62338344 1.413 ENSMUST00000079300.6
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr19_-_45742873 1.316 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
Fgf8


fibroblast growth factor 8


chr10_+_90829538 1.272 ENSMUST00000179694.2
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.5 GO:0048484 enteric nervous system development(GO:0048484)
0.4 4.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.6 3.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.7 2.0 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.2 1.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 1.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 1.6 GO:0070166 enamel mineralization(GO:0070166)
0.3 1.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 1.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 1.3 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.6 1.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.1 GO:1903975 regulation of glial cell migration(GO:1903975)
0.0 1.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.3 1.0 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 1.0 GO:0046033 AMP metabolic process(GO:0046033)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 0.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 5.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 4.1 GO:0005604 basement membrane(GO:0005604)
0.0 2.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.2 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.5 GO:1990075 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 4.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 3.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 1.9 GO:0034711 inhibin binding(GO:0034711)
0.6 1.8 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.8 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.2 1.6 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.1 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 1.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 1.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 1.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.4 1.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 1.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 1.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.8 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)